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ChemicalBook >> CAS DataBase List >> Doxofylline

Doxofylline

Doxofylline price.
  • $10 - $1235
  • Product name: Doxofylline
  • CAS: 69975-86-6
  • MF: C11H14N4O4
  • MW: 266.25
  • EINECS:274-239-6
  • MDL Number:MFCD00865218
  • Synonyms:DOXOFYLLINE;2-(7’-teofillinmetil)-1,3-diossolano ;Doxofyliine;7-(1,3-dioxolan-2-ylmethyl)-1,3-dimethyl-purine-2,6-dione;DOXOFYLLINE [7-(1,3-DIOXOLAN-2-YLMETHYL)-3,7-DIHYDRO-1,3-DIMETHYL-1H-PURINE-2,6-DIONE];MAXIVENT;Ansirnar;Doxof3rlline
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  • 10mM(in1mLDMSO)
  • Manufactureraablocks
  • Product numberAA00IBX4
  • Product description7-(1,3-Dioxolan-2-ylmethyl)-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione ≥98%
  • Packaging1g
  • Price$10
  • Updated2026-05-29
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  • Manufactureraablocks
  • Product numberAA00IBX4
  • Product description7-(1,3-Dioxolan-2-ylmethyl)-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione ≥98%
  • Packaging5g
  • Price$16
  • Updated2026-05-29
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  • Manufactureraablocks
  • Product numberAA00IBX4
  • Product description7-(1,3-Dioxolan-2-ylmethyl)-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione ≥98%
  • Packaging25g
  • Price$64
  • Updated2026-05-29
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  • Manufactureraablocks
  • Product numberAA00IBX4
  • Product description7-(1,3-Dioxolan-2-ylmethyl)-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione ≥98%
  • Packaging100g
  • Price$165
  • Updated2026-05-29
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  • Manufactureraablocks
  • Product numberAA00IBX4
  • Product description7-(1,3-Dioxolan-2-ylmethyl)-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione ≥98%
  • Packaging500g
  • Price$674
  • Updated2026-05-29
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  • ManufacturerAHH
  • Product numberMT-50720
  • Product descriptionDoxofylline 97%
  • Packaging25g
  • Price$530
  • Updated2026-05-25
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  • ManufacturerAHH
  • Product numberMT-50720
  • Product descriptionDoxofylline 97%
  • Packaging25g
  • Price$530
  • Updated2026-05-26
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  • ManufacturerAHH
  • Product numberMT-50720
  • Product descriptionDoxofylline 98%
  • Packaging25g
  • Price$530
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product numberH488
  • Product descriptionDoxofylline
  • Packaging25g
  • Price$576
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberB1734
  • Product descriptionDoxofylline
  • Packaging10mM(in1mLDMSO)
  • Price$55
  • Updated2026-05-06
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  • ManufacturerApexBio Technology
  • Product numberB1734
  • Product descriptionDoxofylline
  • Packaging50mg
  • Price$50
  • Updated2026-05-06
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  • ManufacturerAvaChem
  • Product number1651
  • Product descriptionDoxofylline
  • Packaging1g
  • Price$169
  • Updated2026-05-22
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  • ManufacturerAvaChem
  • Product number1651
  • Product descriptionDoxofylline
  • Packaging25mg
  • Price$19
  • Updated2026-05-22
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  • ManufacturerAvaChem
  • Product number1651
  • Product descriptionDoxofylline
  • Packaging100mg
  • Price$39
  • Updated2026-05-22
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  • ManufacturerAvaChem
  • Product number1651
  • Product descriptionDoxofylline
  • Packaging100mg
  • Price$49
  • Updated2021-12-16
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  • ManufacturerAvaChem
  • Product number1651
  • Product descriptionDoxofylline
  • Packaging1g
  • Price$169
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00IBX4 7-(1,3-Dioxolan-2-ylmethyl)-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione ≥98% 1g $10 2026-05-29 Buy
aablocks AA00IBX4 7-(1,3-Dioxolan-2-ylmethyl)-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione ≥98% 5g $16 2026-05-29 Buy
aablocks AA00IBX4 7-(1,3-Dioxolan-2-ylmethyl)-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione ≥98% 25g $64 2026-05-29 Buy
aablocks AA00IBX4 7-(1,3-Dioxolan-2-ylmethyl)-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione ≥98% 100g $165 2026-05-29 Buy
aablocks AA00IBX4 7-(1,3-Dioxolan-2-ylmethyl)-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione ≥98% 500g $674 2026-05-29 Buy
AHH MT-50720 Doxofylline 97% 25g $530 2026-05-25 Buy
AHH MT-50720 Doxofylline 97% 25g $530 2026-05-26 Buy
AHH MT-50720 Doxofylline 98% 25g $530 2021-12-16 Buy
AK Scientific H488 Doxofylline 25g $576 2021-12-16 Buy
ApexBio Technology B1734 Doxofylline 10mM(in1mLDMSO) $55 2026-05-06 Buy
ApexBio Technology B1734 Doxofylline 50mg $50 2026-05-06 Buy
AvaChem 1651 Doxofylline 1g $169 2026-05-22 Buy
AvaChem 1651 Doxofylline 25mg $19 2026-05-22 Buy
AvaChem 1651 Doxofylline 100mg $39 2026-05-22 Buy
AvaChem 1651 Doxofylline 100mg $49 2021-12-16 Buy
AvaChem 1651 Doxofylline 1g $169 2021-12-16 Buy

Properties

Melting point :144-146°C
Boiling point :409.46°C (rough estimate)
Density :1.2896 (rough estimate)
refractive index :1.6000 (estimate)
RTECS :XH5135000
storage temp. :under inert gas (nitrogen or Argon) at 2-8°C
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
pka :0.42±0.70(Predicted)
color :White to Off-White
Water Solubility :Soluble
Merck :14,3438
InChI :InChI=1S/C11H14N4O4/c1-13-9-8(10(16)14(2)11(13)17)15(6-12-9)5-7-18-3-4-19-7/h6-7H,3-5H2,1-2H3
InChIKey :HWXIGFIVGWUZAO-UHFFFAOYSA-N
SMILES :N1(CC2OCCO2)C2=C(N(C)C(=O)N(C)C2=O)N=C1
CAS DataBase Reference :69975-86-6(CAS DataBase Reference)

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P330 Rinse mouth.
P501 Dispose of contents/container to..…

Description

Doxofylline is a methylxanthine bronchodilator that has been examined in clinical trials involving patients with either bronchial asthma or chronic obstructive pulmonary disease. Its mechanism of action is related to its ability to inhibit phosphodiesterase activity and, thus, increase cAMP. Compared to other xanthine derivatives, which have direct arrhythmogenic effects, doxofylline demonstrates decreased affinity towards adenosine A1 and A2 receptors, does not interfere with calcium influx into cells, and does not antagonize the action of calcium-channel blockers.

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