Entospletinib (GS-9973)
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- $13 - $2841
- Product name: Entospletinib (GS-9973)
- CAS: 1229208-44-9
- MF: C23H21N7O
- MW: 411.46
- EINECS:-0
- MDL Number:MFCD28099806
- Synonyms:GS-9973;6-(1H-Indazol-6-yl)-N-[4-(4-morpholinyl)phenyl]imidazo[1,2-a]pyrazin-8-amine;Entospletinib (GS-9973);Entospletinib Dimesylate;GS-9973, Entospletinib;GS-9973;GS 9973;CS-1602;GS9973; GS 9973; ENTOSPLETINIB
74 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Biosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- TRC
- Usbiological
Package
- 10mM(1mLinDMSO)
- 10mM*1mLinDMSO(Solid+Solvent)
- 10.00mg
- 50.00mg
- 100.00mg
- 200mg
- 10mM*1mLinDMSO(Solution)
- 10mM*1mLinDMSO
- 250mg
- 1mg
- 10mM(in 1mL DMSO)
- 5mg
- 10mg
- 25MG
- 50mg
- 100mg
- 1g
- 10mM(in1mLDMSO)
- Manufactureraablocks
- Product numberAA000JOP
- Product description6-(1H-Indazol-6-yl)-N-[4-(4-morpholinyl)phenyl]imidazo[1,2-a]pyrazin-8-amine 99+%
- Packaging1mg
- Price$13
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000JOP
- Product description6-(1H-Indazol-6-yl)-N-[4-(4-morpholinyl)phenyl]imidazo[1,2-a]pyrazin-8-amine 99+%
- Packaging5mg
- Price$28
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000JOP
- Product description6-(1H-Indazol-6-yl)-N-[4-(4-morpholinyl)phenyl]imidazo[1,2-a]pyrazin-8-amine 99+%
- Packaging10mg
- Price$40
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000JOP
- Product description6-(1H-Indazol-6-yl)-N-[4-(4-morpholinyl)phenyl]imidazo[1,2-a]pyrazin-8-amine 99+%
- Packaging50mg
- Price$105
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000JOP
- Product description6-(1H-Indazol-6-yl)-N-[4-(4-morpholinyl)phenyl]imidazo[1,2-a]pyrazin-8-amine 99+%
- Packaging100mg
- Price$175
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000JOP
- Product description6-(1H-Indazol-6-yl)-N-[4-(4-morpholinyl)phenyl]imidazo[1,2-a]pyrazin-8-amine 98%
- Packaging1g
- Price$1357
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberT101909
- Product description6-(1H-indazol-6-yl)-N-(4-morpholinophenyl)imidazo[1,2-a]pyrazin-8-amine 98%
- Packaging1G
- Price$808
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberT101909
- Product description6-(1H-indazol-6-yl)-N-(4-morpholinophenyl)imidazo[1,2-a]pyrazin-8-amine 98%
- Packaging1G
- Price$808
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberT101909
- Product description6-(1H-indazol-6-yl)-N-(4-morpholinophenyl)imidazo[1,2-a]pyrazin-8-amine 98%
- Packaging100MG
- Price$157
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberT101909
- Product description6-(1H-indazol-6-yl)-N-(4-morpholinophenyl)imidazo[1,2-a]pyrazin-8-amine 98%
- Packaging100MG
- Price$157
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberT101909
- Product description6-(1H-indazol-6-yl)-N-(4-morpholinophenyl)imidazo[1,2-a]pyrazin-8-amine 98%
- Packaging25MG
- Price$64
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberT101909
- Product description6-(1H-indazol-6-yl)-N-(4-morpholinophenyl)imidazo[1,2-a]pyrazin-8-amine 98%
- Packaging25MG
- Price$64
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number2440AH
- Product description6-(1H-Indazol-6-yl)-N-(4-morpholinophenyl)imidazo[1,2-a]pyrazin-8-amine
- Packaging10mg
- Price$217
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0026214
- Product descriptionGS-9973 95.00%
- Packaging5MG
- Price$496.75
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB3553
- Product descriptionGS-9973
- Packaging10mM(in 1mL DMSO)
- Price$150
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB3553
- Product descriptionGS-9973
- Packaging10mg
- Price$102
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA000JOP | 6-(1H-Indazol-6-yl)-N-[4-(4-morpholinyl)phenyl]imidazo[1,2-a]pyrazin-8-amine 99+% | 1mg | $13 | 2026-05-25 | Buy |
| aablocks | AA000JOP | 6-(1H-Indazol-6-yl)-N-[4-(4-morpholinyl)phenyl]imidazo[1,2-a]pyrazin-8-amine 99+% | 5mg | $28 | 2026-05-25 | Buy |
| aablocks | AA000JOP | 6-(1H-Indazol-6-yl)-N-[4-(4-morpholinyl)phenyl]imidazo[1,2-a]pyrazin-8-amine 99+% | 10mg | $40 | 2026-05-25 | Buy |
| aablocks | AA000JOP | 6-(1H-Indazol-6-yl)-N-[4-(4-morpholinyl)phenyl]imidazo[1,2-a]pyrazin-8-amine 99+% | 50mg | $105 | 2026-05-25 | Buy |
| aablocks | AA000JOP | 6-(1H-Indazol-6-yl)-N-[4-(4-morpholinyl)phenyl]imidazo[1,2-a]pyrazin-8-amine 99+% | 100mg | $175 | 2026-05-25 | Buy |
| aablocks | AA000JOP | 6-(1H-Indazol-6-yl)-N-[4-(4-morpholinyl)phenyl]imidazo[1,2-a]pyrazin-8-amine 98% | 1g | $1357 | 2026-05-25 | Buy |
| ACHEMBLOCK | T101909 | 6-(1H-indazol-6-yl)-N-(4-morpholinophenyl)imidazo[1,2-a]pyrazin-8-amine 98% | 1G | $808 | 2026-05-27 | Buy |
| ACHEMBLOCK | T101909 | 6-(1H-indazol-6-yl)-N-(4-morpholinophenyl)imidazo[1,2-a]pyrazin-8-amine 98% | 1G | $808 | 2026-05-25 | Buy |
| ACHEMBLOCK | T101909 | 6-(1H-indazol-6-yl)-N-(4-morpholinophenyl)imidazo[1,2-a]pyrazin-8-amine 98% | 100MG | $157 | 2026-05-25 | Buy |
| ACHEMBLOCK | T101909 | 6-(1H-indazol-6-yl)-N-(4-morpholinophenyl)imidazo[1,2-a]pyrazin-8-amine 98% | 100MG | $157 | 2026-05-27 | Buy |
| ACHEMBLOCK | T101909 | 6-(1H-indazol-6-yl)-N-(4-morpholinophenyl)imidazo[1,2-a]pyrazin-8-amine 98% | 25MG | $64 | 2026-05-25 | Buy |
| ACHEMBLOCK | T101909 | 6-(1H-indazol-6-yl)-N-(4-morpholinophenyl)imidazo[1,2-a]pyrazin-8-amine 98% | 25MG | $64 | 2026-05-27 | Buy |
| AK Scientific | 2440AH | 6-(1H-Indazol-6-yl)-N-(4-morpholinophenyl)imidazo[1,2-a]pyrazin-8-amine | 10mg | $217 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0026214 | GS-9973 95.00% | 5MG | $496.75 | 2021-12-16 | Buy |
| ApexBio Technology | B3553 | GS-9973 | 10mM(in 1mL DMSO) | $150 | 2021-12-16 | Buy |
| ApexBio Technology | B3553 | GS-9973 | 10mg | $102 | 2021-12-16 | Buy |
Properties
Density :1.45±0.1 g/cm3(Predicted)
storage temp. :Desiccate at -20°C
solubility :insoluble in EtOH; insoluble in H2O; ≥20.55 mg/mL in DMSO
form :solid
pka :12.54±0.40(Predicted)
color :White to gray
InChI :InChI=1S/C23H21N7O/c1-2-17-14-25-28-20(17)13-16(1)21-15-30-8-7-24-23(30)22(27-21)26-18-3-5-19(6-4-18)29-9-11-31-12-10-29/h1-8,13-15H,9-12H2,(H,25,28)(H,26,27)
InChIKey :XSMSNFMDVXXHGJ-UHFFFAOYSA-N
SMILES :C12=NC=CN1C=C(C1=CC3=C(C=C1)C=NN3)N=C2NC1=CC=C(N2CCOCC2)C=C1
storage temp. :Desiccate at -20°C
solubility :insoluble in EtOH; insoluble in H2O; ≥20.55 mg/mL in DMSO
form :solid
pka :12.54±0.40(Predicted)
color :White to gray
InChI :InChI=1S/C23H21N7O/c1-2-17-14-25-28-20(17)13-16(1)21-15-30-8-7-24-23(30)22(27-21)26-18-3-5-19(6-4-18)29-9-11-31-12-10-29/h1-8,13-15H,9-12H2,(H,25,28)(H,26,27)
InChIKey :XSMSNFMDVXXHGJ-UHFFFAOYSA-N
SMILES :C12=NC=CN1C=C(C1=CC3=C(C=C1)C=NN3)N=C2NC1=CC=C(N2CCOCC2)C=C1
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||||||||||||||||
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Description
Entospletinib (GS-9973) is an orally bioavailable, selective Syk inhibitor with IC50 of 7.7 nM in a cell-free assay and showed 13-to >1000-fold cellular selectivity for Syk over other kinases(including Jak2, ckit, Flt3, Ret, KDR) as assessed by target protein phosphorylation or functional response.More related product prices
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