一二三四区视频,亚洲少妇熟女色,日本久热无码视频网,欧美国产日韩大尺度,亚洲a视频,久久少妇一区二区,日韩999无码视频,刺激久久久久久久,啊啊啊啊不要啊在线

Welcome to chemicalbook!
010-86108875
RFQ
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook >> CAS DataBase List >> FLUTICASONE FUROATE

FLUTICASONE FUROATE

FLUTICASONE FUROATE price.
  • $10 - $2578
  • Product name: FLUTICASONE FUROATE
  • CAS: 397864-44-7
  • MF: C27H29F3O6S
  • MW: 538.58
  • EINECS:222-789-2
  • MDL Number:MFCD09954122
  • Synonyms:FLUTICASONE FUROATE;Androsta-1,4-diene-17-carbothioic acid, 6,9-difluoro-17-((2- furanylcarbonyl)oxy)-11-hydroxy-16-methyl-3-oxo-, S-(fluoromethyl) ester, (6alpha,11beta,16alpha,17alpha)-;Gw 685698x;Unii-js86977wnv;Veramyst;(6α,11β,16α,17α)-6,9-Difluoro-17-[(2-furanylcarbonyl)oxy]-11-hydroxy-16-Methyl-3-oxoandrosta-1,4-diene-17-carbothioic Acid S-(FluoroMethyl) Ester;AllerMist;GSK 685 698
86 prices
Selected condition:
Brand
  • aablocks
  • ACHEMBLOCK
  • American Custom Chemicals Corporation
  • Arctom
  • Axon Medchem
  • Biosynth
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • Sigma-Aldrich
  • TCI Chemical
  • TRC
  • Usbiological
Package
  • 10mM*1mLinDMSO(Solution)
  • 5mg
  • 1mg
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 200mg
  • 250mg
  • 500mg
  • 0.5g
  • 1g
  • 2g
  • 5g
  • 10g
  • Manufactureraablocks
  • Product numberAA00C90G
  • Product description(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-Difluoro-17-(((fluoromethyl)thio)carbonyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl furan-2-carboxylate ≥98%
  • Packaging5mg
  • Price$10
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00C90G
  • Product description(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-Difluoro-17-(((fluoromethyl)thio)carbonyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl furan-2-carboxylate ≥98%
  • Packaging25mg
  • Price$16
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00C90G
  • Product description(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-Difluoro-17-(((fluoromethyl)thio)carbonyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl furan-2-carboxylate ≥98%
  • Packaging50mg
  • Price$21
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00C90G
  • Product description(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-Difluoro-17-(((fluoromethyl)thio)carbonyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl furan-2-carboxylate ≥98%
  • Packaging100mg
  • Price$30
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00C90G
  • Product description(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-Difluoro-17-(((fluoromethyl)thio)carbonyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl furan-2-carboxylate ≥98%
  • Packaging250mg
  • Price$60
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00C90G
  • Product description(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-Difluoro-17-(((fluoromethyl)thio)carbonyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl furan-2-carboxylate ≥98%
  • Packaging1g
  • Price$186
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00C90G
  • Product description(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-Difluoro-17-(((fluoromethyl)thio)carbonyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl furan-2-carboxylate ≥98%
  • Packaging5g
  • Price$668
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberX182400
  • Product descriptionFluticasone Furoate 95%
  • Packaging5G
  • Price$320
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberX182400
  • Product descriptionFluticasone Furoate 95%
  • Packaging1G
  • Price$110
  • Updated2026-05-27
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberRDL0006841
  • Product descriptionFLUTICASONE FUROATE-D3 95.00%
  • Packaging5MG
  • Price$495.1
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberHY-15234R
  • Product descriptionFluticasone furoate (Standard) 99.49%
  • Packaging100mg
  • Price$835
  • Updated2026-05-25
  • Buy
  • ManufacturerArctom
  • Product numberHY-15234R
  • Product descriptionFluticasone furoate (Standard) 99.49%
  • Packaging100mg
  • Price$835
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-15234
  • Product descriptionFluticasonefuroate 98.90%
  • Packaging200mg
  • Price$333
  • Updated2026-05-25
  • Buy
  • ManufacturerArctom
  • Product numberHY-15234
  • Product descriptionFluticasonefuroate 98.90%
  • Packaging200mg
  • Price$333
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-15234R
  • Product descriptionFluticasone furoate (Standard) 99.49%
  • Packaging25mg
  • Price$371
  • Updated2026-05-25
  • Buy
  • ManufacturerArctom
  • Product numberHY-15234R
  • Product descriptionFluticasone furoate (Standard) 99.49%
  • Packaging25mg
  • Price$371
  • Updated2026-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00C90G (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-Difluoro-17-(((fluoromethyl)thio)carbonyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl furan-2-carboxylate ≥98% 5mg $10 2026-05-28 Buy
aablocks AA00C90G (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-Difluoro-17-(((fluoromethyl)thio)carbonyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl furan-2-carboxylate ≥98% 25mg $16 2026-05-28 Buy
aablocks AA00C90G (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-Difluoro-17-(((fluoromethyl)thio)carbonyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl furan-2-carboxylate ≥98% 50mg $21 2026-05-28 Buy
aablocks AA00C90G (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-Difluoro-17-(((fluoromethyl)thio)carbonyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl furan-2-carboxylate ≥98% 100mg $30 2026-05-28 Buy
aablocks AA00C90G (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-Difluoro-17-(((fluoromethyl)thio)carbonyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl furan-2-carboxylate ≥98% 250mg $60 2026-05-28 Buy
aablocks AA00C90G (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-Difluoro-17-(((fluoromethyl)thio)carbonyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl furan-2-carboxylate ≥98% 1g $186 2026-05-28 Buy
aablocks AA00C90G (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-Difluoro-17-(((fluoromethyl)thio)carbonyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl furan-2-carboxylate ≥98% 5g $668 2026-05-28 Buy
ACHEMBLOCK X182400 Fluticasone Furoate 95% 5G $320 2026-05-27 Buy
ACHEMBLOCK X182400 Fluticasone Furoate 95% 1G $110 2026-05-27 Buy
American Custom Chemicals Corporation RDL0006841 FLUTICASONE FUROATE-D3 95.00% 5MG $495.1 2021-12-16 Buy
Arctom HY-15234R Fluticasone furoate (Standard) 99.49% 100mg $835 2026-05-25 Buy
Arctom HY-15234R Fluticasone furoate (Standard) 99.49% 100mg $835 2026-05-26 Buy
Arctom HY-15234 Fluticasonefuroate 98.90% 200mg $333 2026-05-25 Buy
Arctom HY-15234 Fluticasonefuroate 98.90% 200mg $333 2026-05-26 Buy
Arctom HY-15234R Fluticasone furoate (Standard) 99.49% 25mg $371 2026-05-25 Buy
Arctom HY-15234R Fluticasone furoate (Standard) 99.49% 25mg $371 2026-05-26 Buy

Properties

Melting point :250-252°C (dec.)
Boiling point :625.2±55.0 °C(Predicted)
Density :1.39
storage temp. :-20°C Freezer
solubility :Chloroform (Slightly, Heated, Sonicated), Methanol (Slightly)
pka :12.52±0.70(Predicted)
form :Solid
color :White to Off-White
InChIKey :XTULMSXFIHGYFS-XEVZMEAZNA-N
SMILES :[C@]12(C)C=CC(=O)C=C1[C@@H](F)C[C@@]1([H])[C@]3([H])C[C@@H](C)[C@@](C(=O)SCF)(OC(=O)C4=CC=CO4)[C@@]3(C)C[C@H](O)[C@]21F |&1:0,8,11,13,16,18,32,35,37,r|

Safety Information

Symbol(GHS): Health Hazard (GHS08)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Fluticasone furoate is a new corticosteroid derivative launched as a nasal spray for the treatment of seasonal and perennial allergic rhinitis in adults and in children aged ≥2 years. It is structurally closely related to the previously marketed intranasal corticosteroid fluticasone propionate (FP). Both of these steroids contain the unusual S-fluoromethyl carbothioate group, which confers high lipophilicity and hence enhanced binding and retention of the drug by the nasal tissue. Additionally, the carbothioate group rapidly undergoes first-pass metabolism by CYP3A4, thus minimizing systemic exposure of the parent drug. Fluticasone furoate is a potent ligand for the glucocorticoid receptor (GR), with a relative receptor affinity (RRA) of 2,989 with reference to dexamethasone RRA of 100.
Following intranasal administration, most of the dose is eventually swallowed and undergoes incomplete absorption and extensive firstpass metabolism in the liver and gut, resulting in negligible systemic exposure. Pharmacokinetic studies using oral solution dosing and intravenous dosing show that at least 30% of fluticasone furoate is absorbed and then rapidly cleared from plasma. The most common adverse reactions (W1% incidence) included headache, epistatix, sinus and throat pain, nasal ulceration, back pain, pyrexia, and cough. Fluticasone furoate is chemically derived starting from a readily available corticosteroid, 6a,9a-difluoro-11b,17a-dihydroxy-16a-methyl-3-oxoandrosta-1,4-diene-17b-carboxylic acid, by first converting the carboxylic acid group to the corresponding carbothioic acid via activation with carbonyl diimidazole followed by reaction with hydrogen sulfide gas. Subsequently, selective acylation of the 17a-hydroxyl group with 2-furoyl chloride and alkylation of the 17b-carbothioic acid group with bromofluoromethane under basic conditions provides fluticasone furoate.

石台县| 潼南县| 常山县| 壤塘县| 洪雅县| 永安市| 建水县| 东阿县| 西吉县| 张家川| 历史| 泽库县| 交口县| 珲春市| 楚雄市| 广安市| 金华市| 泸水县| 博湖县| 昭觉县| 石河子市| 乳山市| 湖口县| 乌鲁木齐县| 清水县| 宁安市| 名山县| 金沙县| 灵台县| 府谷县| 乌兰县| 三江| 清镇市| 新郑市| 铜陵市| 武夷山市| 广河县| 太原市| 武隆县| 璧山县| 辽源市|