Gimeracil
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- $5 - $1686.3
- Product name: Gimeracil
- CAS: 103766-25-2
- MF: C5H4ClNO2
- MW: 145.54
- EINECS:1312995-182-4
- MDL Number:MFCD08458352
- Synonyms:GIMERACIL;gimestat;5-Chloro-4-hydroxy-2(1H)-pyridinone;5-Chloro-4-hydroxy-2-pyridone;2(1H)-Pyridinone,5-chloro-4-hydroxy-(9CI);5-chloropyridine-2,4-diol;2(1H)-Pyridinone, 5-chloro-4-hydroxy-;Gimeracil,(CDHP)
111 prices
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Brand
- aablocks
- Activate Scientific
- Adipogen Life Sciences
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Apolloscientific
- Arctom
- AvaChem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- Chem-Impex
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Labseeker
- Sigma-Aldrich
- TCI Chemical
- TRC
- Usbiological
Package
- 10μg
- 50ug
- 100ug
- 5mg
- 10mg
- 25MG
- 50ul
- 50mg
- 100ul
- 100mg
- 200ul
- 0.25G
- 250mg
- 500mg
- 1g
- 5g
- 10g
- 25g
- 50g
- 100g
- 250g
- 2.5kg
- 48Tests
- 10mM(in 1mL DMSO)
- 500g
- 10mM(in1mLDMSO)
- Manufactureraablocks
- Product numberAA0038X6
- Product description5-Chloro-2,4-Dihydroxypyridine 98%
- Packaging100mg
- Price$8
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0038X6
- Product description5-Chloro-2,4-Dihydroxypyridine ≥98%
- Packaging250mg
- Price$10
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0038X6
- Product description5-Chloro-2,4-Dihydroxypyridine 98%
- Packaging25g
- Price$16
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0038X6
- Product description5-Chloro-2,4-Dihydroxypyridine ≥98%
- Packaging1g
- Price$11
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0038X6
- Product description5-Chloro-2,4-Dihydroxypyridine 98%
- Packaging5g
- Price$12
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0038X6
- Product description5-Chloro-2,4-Dihydroxypyridine 98%
- Packaging100g
- Price$49
- Updated2026-05-28
- Buy
- ManufacturerActivate Scientific
- Product numberAS28441
- Product description5-Chloro-4-hydroxy-2(1H)-pyridone 98%
- Packaging5g
- Price$20
- Updated2026-06-04
- Buy
- ManufacturerActivate Scientific
- Product numberAS28441
- Product description5-Chloro-4-hydroxy-2(1H)-pyridone 98%
- Packaging25g
- Price$53
- Updated2026-06-04
- Buy
- ManufacturerActivate Scientific
- Product numberAS28441
- Product description5-Chloro-4-hydroxy-2(1H)-pyridone 98%
- Packaging100g
- Price$163
- Updated2026-06-04
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberCDX-G0209-G001
- Product descriptionGimeracil ≥99%
- Packaging1g
- Price$66
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberCDX-G0209-G001
- Product descriptionGimeracil ≥99%
- Packaging1g
- Price$59
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberCDX-G0209-G005
- Product descriptionGimeracil ≥99%
- Packaging5g
- Price$250
- Updated2026-05-06
- Buy
- ManufacturerAK Scientific
- Product numberH836
- Product descriptionGimeracil 98%(HPLC)
- Packaging1g
- Price$16
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberJ91959
- Product descriptionGimeracil 95%
- Packaging5g
- Price$17
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberH836
- Product descriptionGimeracil 98%(HPLC)
- Packaging5g
- Price$19
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberJ91959
- Product descriptionGimeracil 95%
- Packaging1g
- Price$12
- Updated2026-06-04
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA0038X6 | 5-Chloro-2,4-Dihydroxypyridine 98% | 100mg | $8 | 2026-05-28 | Buy |
| aablocks | AA0038X6 | 5-Chloro-2,4-Dihydroxypyridine ≥98% | 250mg | $10 | 2026-05-28 | Buy |
| aablocks | AA0038X6 | 5-Chloro-2,4-Dihydroxypyridine 98% | 25g | $16 | 2026-05-28 | Buy |
| aablocks | AA0038X6 | 5-Chloro-2,4-Dihydroxypyridine ≥98% | 1g | $11 | 2026-05-28 | Buy |
| aablocks | AA0038X6 | 5-Chloro-2,4-Dihydroxypyridine 98% | 5g | $12 | 2026-05-28 | Buy |
| aablocks | AA0038X6 | 5-Chloro-2,4-Dihydroxypyridine 98% | 100g | $49 | 2026-05-28 | Buy |
| Activate Scientific | AS28441 | 5-Chloro-4-hydroxy-2(1H)-pyridone 98% | 5g | $20 | 2026-06-04 | Buy |
| Activate Scientific | AS28441 | 5-Chloro-4-hydroxy-2(1H)-pyridone 98% | 25g | $53 | 2026-06-04 | Buy |
| Activate Scientific | AS28441 | 5-Chloro-4-hydroxy-2(1H)-pyridone 98% | 100g | $163 | 2026-06-04 | Buy |
| Adipogen Life Sciences | CDX-G0209-G001 | Gimeracil ≥99% | 1g | $66 | 2026-05-06 | Buy |
| Adipogen Life Sciences | CDX-G0209-G001 | Gimeracil ≥99% | 1g | $59 | 2021-12-16 | Buy |
| Adipogen Life Sciences | CDX-G0209-G005 | Gimeracil ≥99% | 5g | $250 | 2026-05-06 | Buy |
| AK Scientific | H836 | Gimeracil 98%(HPLC) | 1g | $16 | 2026-06-04 | Buy |
| AK Scientific | J91959 | Gimeracil 95% | 5g | $17 | 2026-06-04 | Buy |
| AK Scientific | H836 | Gimeracil 98%(HPLC) | 5g | $19 | 2026-06-04 | Buy |
| AK Scientific | J91959 | Gimeracil 95% | 1g | $12 | 2026-06-04 | Buy |
Properties
Melting point :274 °C
Boiling point :255.1±40.0 °C(Predicted)
Density :1.56±0.1 g/cm3(Predicted)
storage temp. :Inert atmosphere,Store in freezer, under -20°C
solubility :Soluble in DMSO (up to 5 mg/ml).
form :solid
pka :4.50±1.00(Predicted)
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChI :InChI=1S/C5H4ClNO2/c6-3-2-7-5(9)1-4(3)8/h1-2H,(H2,7,8,9)
InChIKey :ZPLQIPFOCGIIHV-UHFFFAOYSA-N
SMILES :C1(=O)NC=C(Cl)C(O)=C1
CAS DataBase Reference :103766-25-2(CAS DataBase Reference)
Boiling point :255.1±40.0 °C(Predicted)
Density :1.56±0.1 g/cm3(Predicted)
storage temp. :Inert atmosphere,Store in freezer, under -20°C
solubility :Soluble in DMSO (up to 5 mg/ml).
form :solid
pka :4.50±1.00(Predicted)
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChI :InChI=1S/C5H4ClNO2/c6-3-2-7-5(9)1-4(3)8/h1-2H,(H2,7,8,9)
InChIKey :ZPLQIPFOCGIIHV-UHFFFAOYSA-N
SMILES :C1(=O)NC=C(Cl)C(O)=C1
CAS DataBase Reference :103766-25-2(CAS DataBase Reference)
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
5-Fluorouracil is a pyrimidine analog that irreversibly inhibits thymidylate synthase, blocking the synthesis of thymidine, which is required for DNA synthesis. It has been widely used to treat many gastrointestinal tract adenocarcinomas with mixed clinical efficacy. Gimeracil is an inhibitor of dihydropyrimidine dehydrogenase, the rate limiting enzyme for the catabolism of pyrimidines, including 5-fluorouracil. It has been administered concomitantly with 5-fluorouracil in a chemotherapy regimen termed S-1 to block 5-fluorouracil degradation, thus prolonging circulating 5-fluorouracil concentrations. Furthermore, at 1 mM gimeracil has been shown to inhibit homologous recombination in the repair of DNA double strand breaks, which can sensitize cancer cells to radiotherapy.More related product prices
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$4-2798.99
Suppliers and manufacturers
Moxin Chemicals
Gimeracil
CAS:103766-25-2
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Gimeracil
CAS:103766-25-2