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ChemicalBook >> CAS DataBase List >> K-Ras(G12C) inhibitor 9

K-Ras(G12C) inhibitor 9

K-Ras(G12C) inhibitor 9 price.
  • $44 - $2995
  • Product name: K-Ras(G12C) inhibitor 9
  • CAS: 1469337-91-4
  • MF: C16H21ClIN3O4S
  • MW: 513.78
  • EINECS:-0
  • MDL Number:MFCD28143916
  • Synonyms:K-Ras(G12C) inhibitor 9;N-[1-[2-[(4-chloro-5-iodo-2-methoxyphenyl)amino]acetyl]-4-piperidinyl]-ethenesulfonamide;K RAS INHIBITOR-9; KRAS INHIBITOR 9;K-RAS inhibitor 9;Ethenesulfonamide, N-[1-[2-[(4-chloro-5-iodo-2-methoxyphenyl)amino]acetyl]-4-piperidinyl]-;K-Ras(G12C) inhibitor 9 USP/EP/BP;K-Ras(G-12C) inhibitor 9,KRas(G12C) inhibitor 9,Ras,Inhibitor,K-Ras(G12C) inhibitor 9,inhibit,K Ras(G12C) inhibitor 9;K-Ras(GI2C) Inhibitor 9
34 prices
Selected condition:
Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • ApexBio Technology
  • Biosynth
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • TRC
Package
  • 10mM*1mLinDMSO
  • 1mg
  • 2mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • Manufactureraablocks
  • Product numberAA00ARV6
  • Product descriptionN-[1-[2-[(4-Chloro-5-iodo-2-methoxyphenyl)amino]acetyl]-4-piperidinyl]ethenesulfonamide
  • Packaging5mg
  • Price$80
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00ARV6
  • Product descriptionN-[1-[2-[(4-Chloro-5-iodo-2-methoxyphenyl)amino]acetyl]-4-piperidinyl]ethenesulfonamide
  • Packaging10mg
  • Price$113
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00ARV6
  • Product descriptionN-[1-[2-[(4-Chloro-5-iodo-2-methoxyphenyl)amino]acetyl]-4-piperidinyl]ethenesulfonamide
  • Packaging1mg
  • Price$44
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00ARV6
  • Product descriptionN-[1-[2-[(4-Chloro-5-iodo-2-methoxyphenyl)amino]acetyl]-4-piperidinyl]ethenesulfonamide
  • Packaging25mg
  • Price$211
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00ARV6
  • Product descriptionN-[1-[2-[(4-Chloro-5-iodo-2-methoxyphenyl)amino]acetyl]-4-piperidinyl]ethenesulfonamide
  • Packaging50mg
  • Price$297
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00ARV6
  • Product descriptionN-[1-[2-[(4-Chloro-5-iodo-2-methoxyphenyl)amino]acetyl]-4-piperidinyl]ethenesulfonamide
  • Packaging100mg
  • Price$399
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberT94892
  • Product descriptionK-Ras(G12C) inhibitor 9 98%
  • Packaging25MG
  • Price$210
  • Updated2026-05-25
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberT94892
  • Product descriptionK-Ras(G12C) inhibitor 9 98%
  • Packaging25MG
  • Price$210
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberT94892
  • Product descriptionK-Ras(G12C) inhibitor 9 98%
  • Packaging100MG
  • Price$550
  • Updated2026-05-25
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberT94892
  • Product descriptionK-Ras(G12C) inhibitor 9 98%
  • Packaging100MG
  • Price$550
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product number2501AH
  • Product descriptionK-Ras(G12C)inhibitor9
  • Packaging10mg
  • Price$478
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6002
  • Product descriptionK-Ras(G12C) inhibitor 9
  • Packaging10mg
  • Price$727
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6002
  • Product descriptionK-Ras(G12C) inhibitor 9
  • Packaging25mg
  • Price$1137
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6002
  • Product descriptionK-Ras(G12C) inhibitor 9
  • Packaging5mg
  • Price$472
  • Updated2026-05-06
  • Buy
  • ManufacturerBiosynth
  • Product numberUIC33791
  • Product descriptionK-Ras(G12C) inhibitor 9
  • Packaging25mg
  • Price$1345.25
  • Updated2026-06-05
  • Buy
  • ManufacturerBiosynth
  • Product numberUIC33791
  • Product descriptionK-Ras(G12C) inhibitor 9
  • Packaging50mg
  • Price$1871
  • Updated2026-06-05
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00ARV6 N-[1-[2-[(4-Chloro-5-iodo-2-methoxyphenyl)amino]acetyl]-4-piperidinyl]ethenesulfonamide 5mg $80 2026-05-28 Buy
aablocks AA00ARV6 N-[1-[2-[(4-Chloro-5-iodo-2-methoxyphenyl)amino]acetyl]-4-piperidinyl]ethenesulfonamide 10mg $113 2026-05-28 Buy
aablocks AA00ARV6 N-[1-[2-[(4-Chloro-5-iodo-2-methoxyphenyl)amino]acetyl]-4-piperidinyl]ethenesulfonamide 1mg $44 2026-05-28 Buy
aablocks AA00ARV6 N-[1-[2-[(4-Chloro-5-iodo-2-methoxyphenyl)amino]acetyl]-4-piperidinyl]ethenesulfonamide 25mg $211 2026-05-28 Buy
aablocks AA00ARV6 N-[1-[2-[(4-Chloro-5-iodo-2-methoxyphenyl)amino]acetyl]-4-piperidinyl]ethenesulfonamide 50mg $297 2026-05-28 Buy
aablocks AA00ARV6 N-[1-[2-[(4-Chloro-5-iodo-2-methoxyphenyl)amino]acetyl]-4-piperidinyl]ethenesulfonamide 100mg $399 2026-05-28 Buy
ACHEMBLOCK T94892 K-Ras(G12C) inhibitor 9 98% 25MG $210 2026-05-25 Buy
ACHEMBLOCK T94892 K-Ras(G12C) inhibitor 9 98% 25MG $210 2026-05-27 Buy
ACHEMBLOCK T94892 K-Ras(G12C) inhibitor 9 98% 100MG $550 2026-05-25 Buy
ACHEMBLOCK T94892 K-Ras(G12C) inhibitor 9 98% 100MG $550 2026-05-27 Buy
AK Scientific 2501AH K-Ras(G12C)inhibitor9 10mg $478 2021-12-16 Buy
ApexBio Technology B6002 K-Ras(G12C) inhibitor 9 10mg $727 2026-05-06 Buy
ApexBio Technology B6002 K-Ras(G12C) inhibitor 9 25mg $1137 2026-05-06 Buy
ApexBio Technology B6002 K-Ras(G12C) inhibitor 9 5mg $472 2026-05-06 Buy
Biosynth UIC33791 K-Ras(G12C) inhibitor 9 25mg $1345.25 2026-06-05 Buy
Biosynth UIC33791 K-Ras(G12C) inhibitor 9 50mg $1871 2026-06-05 Buy

Properties

Boiling point :656.3±65.0 °C(Predicted)
Density :1.68±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :Soluble in DMSO
form :crystalline solid
pka :9.68±0.20(Predicted)
color :White to off-white

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

K-Ras(G12C) inhibitor 9 is an irreversible, allosteric inhibitor of the K-Ras(G12C) mutant that causes 100% modification of the protein when used at 10 μM for 24 hours in vitro. K-Ras is a small GTPase that cycles between a GTP-bound active state and a GDP-bound inactive state to turn on downstream Raf kinases to drive cell growth. A G12C mutation in K-Ras blocks GTP hydrolysis, activates K-Ras, and promotes carcinogenesis. Similar K-Ras(G12C) inhibitors significantly reduce GTP affinity relative to GDP, decrease Raf binding, and lower cell viability while increasing apoptosis.

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