L-AP4
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- $56 - $1590.4
- Product name: L-AP4
- CAS: 23052-81-5
- MF: C4H10NO5P
- MW: 183.1
- EINECS:200-258-5
- MDL Number:MFCD00083244
- Synonyms:L-AP4;L(+)-2-AMINO-4-PHOSPHONOBUTANOIC ACID;L-(+)-2-AMINO-4-PHOSPHONOBUTYRIC ACID;L-(+)-2-AMINO-4-PHOSPHONOBUTYRIC ACID (L-AP4);L(+)-2-AMINO-4-PHOSPHONOBUTYRIC ACID 97%;(2S)-2-Amino-4-phosphonobutyric acid;(S)-4-Phosphono-2-aminobutanoic acid;(S)-4-Phosphono-2-aminobutyric acid
55 prices
Selected condition：
Brand
- aablocks
- AK Scientific
- ApexBio Technology
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Sigma-Aldrich
- Thermo Scientific Chemicals
- Tocris
- TRC
- Usbiological
Package
- 10μg
- 50μG
- 1mg
- 0.5mg
- 50
- 10
- 2mg
- 5mg
- 10mg
- 25mg
- 50mg
- 50 μg
- Manufactureraablocks
- Product numberAA00I4FT
- Product descriptionL-AP4 ≥95%
- Packaging1mg
- Price$76
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA00I4FT
- Product descriptionL-AP4 ≥95%
- Packaging5mg
- Price$209
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA00I4FT
- Product descriptionL-AP4 ≥95%
- Packaging10mg
- Price$267
- Updated2026-05-29
- Buy
- ManufacturerAK Scientific
- Product number3480AL
- Product descriptionL-Ap4
- Packaging10mg
- Price$218
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number3480AL
- Product descriptionL-Ap4
- Packaging50mg
- Price$640
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6202
- Product descriptionL-AP4
- Packaging10mg
- Price$402
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB6202
- Product descriptionL-AP4
- Packaging50mg
- Price$1290
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6202
- Product descriptionL-AP4
- Packaging50mg
- Price$1462
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB6202
- Product descriptionL-AP4
- Packaging10mg
- Price$308
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb530414
- Product descriptionGDF5
- Packaging10μg
- Price$822.8
- Updated2021-12-16
- Buy
- ManufacturerBiosynth
- Product numberFA01291
- Product descriptionL-AP4
- Packaging5mg
- Price$1073.5
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberFA01291
- Product descriptionL-AP4
- Packaging50mg
- Price$437.5
- Updated2021-12-16
- Buy
- ManufacturerBiosynth
- Product numberFA01291
- Product descriptionL-AP4
- Packaging2mg
- Price$579.72
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberFA01291
- Product descriptionL-AP4
- Packaging10mg
- Price$1590.4
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberFA01291
- Product descriptionL-AP4
- Packaging0.5mg
- Price$264.13
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberFA01291
- Product descriptionL-AP4
- Packaging1mg
- Price$391.3
- Updated2026-06-04
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00I4FT | L-AP4 ≥95% | 1mg | $76 | 2026-05-29 | Buy |
| aablocks | AA00I4FT | L-AP4 ≥95% | 5mg | $209 | 2026-05-29 | Buy |
| aablocks | AA00I4FT | L-AP4 ≥95% | 10mg | $267 | 2026-05-29 | Buy |
| AK Scientific | 3480AL | L-Ap4 | 10mg | $218 | 2021-12-16 | Buy |
| AK Scientific | 3480AL | L-Ap4 | 50mg | $640 | 2021-12-16 | Buy |
| ApexBio Technology | B6202 | L-AP4 | 10mg | $402 | 2026-05-06 | Buy |
| ApexBio Technology | B6202 | L-AP4 | 50mg | $1290 | 2021-12-16 | Buy |
| ApexBio Technology | B6202 | L-AP4 | 50mg | $1462 | 2026-05-06 | Buy |
| ApexBio Technology | B6202 | L-AP4 | 10mg | $308 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb530414 | GDF5 | 10μg | $822.8 | 2021-12-16 | Buy |
| Biosynth | FA01291 | L-AP4 | 5mg | $1073.5 | 2026-06-04 | Buy |
| Biosynth | FA01291 | L-AP4 | 50mg | $437.5 | 2021-12-16 | Buy |
| Biosynth | FA01291 | L-AP4 | 2mg | $579.72 | 2026-06-04 | Buy |
| Biosynth | FA01291 | L-AP4 | 10mg | $1590.4 | 2026-06-04 | Buy |
| Biosynth | FA01291 | L-AP4 | 0.5mg | $264.13 | 2026-06-04 | Buy |
| Biosynth | FA01291 | L-AP4 | 1mg | $391.3 | 2026-06-04 | Buy |
Properties
Melting point :207-215 °C
Boiling point :491.7±55.0 °C(Predicted)
Density :1.628±0.06 g/cm3(Predicted)
storage temp. :0-6°C
solubility :H2O : 50 mg/mL (273.07 mM; Need ultrasonic)
pka :2.19±0.10(Predicted)
form :solid
color :White
biological source :human
Water Solubility :Soluble to 5 mM in water and to 100 mM in 1eq. NaOH
Sensitive :Light Sensitive
InChI :1S/C4H10NO5P/c5-3(4(6)7)1-2-11(8,9)10/h3H,1-2,5H2,(H,6,7)(H2,8,9,10)/t3-/m0/s1
InChIKey :DDOQBQRIEWHWBT-VKHMYHEASA-N
SMILES :N[C@@H](CCP(O)(O)=O)C(O)=O
CAS DataBase Reference :23052-81-5(CAS DataBase Reference)
Boiling point :491.7±55.0 °C(Predicted)
Density :1.628±0.06 g/cm3(Predicted)
storage temp. :0-6°C
solubility :H2O : 50 mg/mL (273.07 mM; Need ultrasonic)
pka :2.19±0.10(Predicted)
form :solid
color :White
biological source :human
Water Solubility :Soluble to 5 mM in water and to 100 mM in 1eq. NaOH
Sensitive :Light Sensitive
InChI :1S/C4H10NO5P/c5-3(4(6)7)1-2-11(8,9)10/h3H,1-2,5H2,(H,6,7)(H2,8,9,10)/t3-/m0/s1
InChIKey :DDOQBQRIEWHWBT-VKHMYHEASA-N
SMILES :N[C@@H](CCP(O)(O)=O)C(O)=O
CAS DataBase Reference :23052-81-5(CAS DataBase Reference)
Safety Information
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Description
Metabotropic glutamate receptors (mGluR) function to modulate excitatory synaptic transmission in the brain. Eight subtypes (1-8) and multiple splice variants of the mGluR have been identified and grouped based on their pharmacological properties. Group I mGluRs (subtypes 1 and 5) activate the phosphatidyl inositol pathway, while Group II (2 and 3) and Group III (4, 6, 7, and 8) inhibit adenylyl cyclase. L-AP4, an analog of L-glutamic acid, is a selective Group III mGluR agonist that functions presynaptically to suppress glutamate release (IC50 = 2.5 μM). L-AP4 has been shown to depress synaptic transmission in glutamatergic pathways in the hippocampus, olfactory bulb, and retina as well as act as an agonist at the quisqualate-sensitized AP6 site in hippocampus.More related product prices
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