MK-2206 2HCl
|
- $10 - $5132
- Product name: MK-2206 2HCl
- CAS: 1032350-13-2
- MF: C25H22ClN5O
- MW: 443.94
- EINECS:
- MDL Number:MFCD14584463
- Synonyms:8-[4-(1-Aminocyclobutyl)phenyl]-9-phenyl-1,2,4-triazolo[3,4-f][1,6]naphthyridin-3(2H)-one dihydrochloride;8-[4-(1-AMinocyclobutyl)phenyl]-9-phenyl-1,2,4-triazolo[3,4-f][1,6]naphthyridin-3(2H)-one Hydrochloride;8-(4-(1-aminocyclobutyl)phenyl)-9-phenyl-[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3(2H)-one;8-[4-(1-Aminocyclobutyl)phenyl]-9-phenyl-1,2,4-triazolo[3,4-f][1,6]naphthyridin-3(2H)-one dihydrochloride MK-2206;MK-2206 8-[4-(1-Aminocyclobutyl)phenyl]-9-phenyl-1,2,4-triazolo[3,4-f][1,6]naphthyridin-3(2H)-one dihydrochloride;MK 2206 (hydrochloride);MK-2206 dihydrochloride, >=98%;MK-2206 2HCL;MK2206
82 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- Adipogen Life Sciences
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Apolloscientific
- Arctom
- AvaChem
- Axon Medchem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- TRC
- Usbiological
Package
- 10mM*1mLinDMSO(Solution)
- 1000mg
- 10mM*1mLinDMSO(Solid+Solvent)
- 200mg
- 500mg
- 5mg
- 100.00mg
- 1.00g
- 250.00mg
- 10mM*1mLinDMSO
- 10mM(in1mLDMSO)
- 500ug
- 1mg
- 1unit
- 10mg
- 25MG
- 50mg
- 100mg
- 1g
- EvaluationSample
- 250mg
- Manufactureraablocks
- Product numberAA008TF8
- Product descriptionMK-2206 dihydrochloride 98%
- Packaging5mg
- Price$15
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008TF8
- Product descriptionMK-2206 dihydrochloride ≥98%
- Packaging10mg
- Price$25
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008TF8
- Product descriptionMK-2206 dihydrochloride ≥98%
- Packaging50mg
- Price$90
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008TF8
- Product descriptionMK-2206 dihydrochloride 98%
- Packaging100mg
- Price$142
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008TF8
- Product descriptionMK-2206 dihydrochloride 98%
- Packaging250mg
- Price$242
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008TF8
- Product descriptionMK-2206 dihydrochloride 95%
- Packaging1g
- Price$785
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberG-6725
- Product descriptionMK-2206 dihydrochloride 98%
- Packaging1G
- Price$495
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberG-6725
- Product descriptionMK-2206 dihydrochloride 98%
- Packaging100MG
- Price$110
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberG-6725
- Product descriptionMK-2206 dihydrochloride 98%
- Packaging25MG
- Price$45
- Updated2026-05-27
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1162-M001
- Product descriptionMK-2206 dihydrochloride ≥95%
- Packaging1mg
- Price$76
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1162-M005
- Product descriptionMK-2206 dihydrochloride ≥95%
- Packaging5mg
- Price$119
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1162-M050
- Product descriptionMK-2206 dihydrochloride ≥95%
- Packaging50mg
- Price$599
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1162-M010
- Product descriptionMK-2206 dihydrochloride ≥95%
- Packaging10mg
- Price$184
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1162-M100
- Product descriptionMK-2206dihydrochloride ≥95%
- Packaging100mg
- Price$1010
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number2181AH
- Product descriptionMK-2206dihydrochloride
- Packaging1g
- Price$1369
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number2181AH
- Product descriptionMK-2206dihydrochloride
- Packaging25mg
- Price$193
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA008TF8 | MK-2206 dihydrochloride 98% | 5mg | $15 | 2026-05-28 | Buy |
| aablocks | AA008TF8 | MK-2206 dihydrochloride ≥98% | 10mg | $25 | 2026-05-28 | Buy |
| aablocks | AA008TF8 | MK-2206 dihydrochloride ≥98% | 50mg | $90 | 2026-05-28 | Buy |
| aablocks | AA008TF8 | MK-2206 dihydrochloride 98% | 100mg | $142 | 2026-05-28 | Buy |
| aablocks | AA008TF8 | MK-2206 dihydrochloride 98% | 250mg | $242 | 2026-05-28 | Buy |
| aablocks | AA008TF8 | MK-2206 dihydrochloride 95% | 1g | $785 | 2026-05-28 | Buy |
| ACHEMBLOCK | G-6725 | MK-2206 dihydrochloride 98% | 1G | $495 | 2026-05-27 | Buy |
| ACHEMBLOCK | G-6725 | MK-2206 dihydrochloride 98% | 100MG | $110 | 2026-05-27 | Buy |
| ACHEMBLOCK | G-6725 | MK-2206 dihydrochloride 98% | 25MG | $45 | 2026-05-27 | Buy |
| Adipogen Life Sciences | SYN-1162-M001 | MK-2206 dihydrochloride ≥95% | 1mg | $76 | 2026-05-06 | Buy |
| Adipogen Life Sciences | SYN-1162-M005 | MK-2206 dihydrochloride ≥95% | 5mg | $119 | 2026-05-06 | Buy |
| Adipogen Life Sciences | SYN-1162-M050 | MK-2206 dihydrochloride ≥95% | 50mg | $599 | 2026-05-06 | Buy |
| Adipogen Life Sciences | SYN-1162-M010 | MK-2206 dihydrochloride ≥95% | 10mg | $184 | 2026-05-06 | Buy |
| Adipogen Life Sciences | SYN-1162-M100 | MK-2206dihydrochloride ≥95% | 100mg | $1010 | 2021-12-16 | Buy |
| AK Scientific | 2181AH | MK-2206dihydrochloride | 1g | $1369 | 2021-12-16 | Buy |
| AK Scientific | 2181AH | MK-2206dihydrochloride | 25mg | $193 | 2021-12-16 | Buy |
Properties
Melting point :>255°C (dec.)
storage temp. :-20°C
solubility :Soluble in DMSO (up to 10 mg/ml with warming)
form :Yellow powder.
color :Yellow
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChIKey :LFYOZCBFOSSLNJ-UHFFFAOYSA-N
SMILES :O=C1NN=C2C3=CC(C4C=CC=CC=4)=C(C4C=CC(C5(CCC5)N)=CC=4)N=C3C=CN12.Cl
storage temp. :-20°C
solubility :Soluble in DMSO (up to 10 mg/ml with warming)
form :Yellow powder.
color :Yellow
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChIKey :LFYOZCBFOSSLNJ-UHFFFAOYSA-N
SMILES :O=C1NN=C2C3=CC(C4C=CC=CC=4)=C(C4C=CC(C5(CCC5)N)=CC=4)N=C3C=CN12.Cl
Safety Information
| Symbol(GHS): |
|
|||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Warning | |||||||||||||||||||||||||||||||||||
| Hazard statements: |
|
|||||||||||||||||||||||||||||||||||
| Precautionary statements: |
|
Description
Three related forms of the kinase Akt (1, 2, 3, also known as protein kinase B isoforms PKBα, β, γ) modulate cell proliferation, metabolism, and survival as well as angiogenesis. MK-2206 is an orally active, allosteric Akt inhibitor that is equally potent toward purified human recombinant Akt1 and Akt2 (IC50s = 5 and 12 nM, respectively) and approximately 5-fold less potent against human Akt3 (IC50 = 65 nM). In combination with other anticancer agents including topoisomerase inhibitors, antimetabolites, antimicrotubule agents, DNA cross-linkers or growth factor inhibitors, MK-2206 has been shown to synergistically inhibit cell proliferation of human cancer cell lines. At 5 μM, MK-2206 significantly enhances apoptosis in hematopoietic cells treated with chemotherapeutics.Related product price
-
Rapamycin
$9-6160 -
871700-17-3
$28-4391.1 -
Pictilisib (GDC-0941)
$16-3563.2
