Nilotinib
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- $10 - $1430
- Product name: Nilotinib
- CAS: 641571-10-0
- MF: C28H22F3N7O
- MW: 529.52
- EINECS:700-544-5
- MDL Number:MFCD09833716
- Synonyms:Nilotinib;Benzamide, 4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-;Nilotinib(TINIBS );4-Methyl-3-((4-(3-pyridinyl)-2-pyrimidinyl)amino)-N-(5-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)phenyl)benzamide;4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)benzamide;Nilotinib & its intermediates;Nilotinib for research;Nilotinib(AMN 107)
116 prices
Selected condition：
Brand
- aablocks
- AccelPharmtech
- ACHEMBLOCK
- Adipogen Life Sciences
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- AvaChem
- Axon Medchem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- ChemScene
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TCI Chemical
- TRC
- Usbiological
Package
- 10mM*1mLinDMSO(Solution)
- 5mg
- 10mg
- 10mM(in1mLDMSO)
- 50mg
- 1mg
- 25mg
- 10mM*1mLinDMSO
- 10mM*1mLinDMSO(Solid+Solvent)
- 20mg
- 100mg
- 200mg
- 250.00mg
- 250mg
- 500mg
- 1.00g
- 1g
- 2g
- 5.00g
- 5g
- 10g
- 25g
- 100g
- 100 mg
- Manufactureraablocks
- Product numberAA0036TM
- Product description4-Methyl-3-((4-(3-pyridinyl)-2-pyrimidinyl)amino)-N-(5-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)phenyl)benzamide 98%
- Packaging1mg
- Price$10
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0036TM
- Product description4-Methyl-3-((4-(3-pyridinyl)-2-pyrimidinyl)amino)-N-(5-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)phenyl)benzamide ≥99%
- Packaging25mg
- Price$10
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0036TM
- Product description4-Methyl-3-((4-(3-pyridinyl)-2-pyrimidinyl)amino)-N-(5-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)phenyl)benzamide 98%
- Packaging100mg
- Price$23
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0036TM
- Product description4-Methyl-3-((4-(3-pyridinyl)-2-pyrimidinyl)amino)-N-(5-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)phenyl)benzamide 98%
- Packaging250mg
- Price$27
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0036TM
- Product description4-Methyl-3-((4-(3-pyridinyl)-2-pyrimidinyl)amino)-N-(5-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)phenyl)benzamide 98%
- Packaging1g
- Price$68
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0036TM
- Product description4-Methyl-3-((4-(3-pyridinyl)-2-pyrimidinyl)amino)-N-(5-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)phenyl)benzamide 98%
- Packaging5g
- Price$196
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0036TM
- Product description4-Methyl-3-((4-(3-pyridinyl)-2-pyrimidinyl)amino)-N-(5-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)phenyl)benzamide 98%
- Packaging10g
- Price$246
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0036TM
- Product description4-Methyl-3-((4-(3-pyridinyl)-2-pyrimidinyl)amino)-N-(5-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)phenyl)benzamide 98%
- Packaging25g
- Price$540
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0036TM
- Product description4-Methyl-3-((4-(3-pyridinyl)-2-pyrimidinyl)amino)-N-(5-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)phenyl)benzamide 98%
- Packaging100g
- Price$1430
- Updated2026-05-28
- Buy
- ManufacturerAccelPharmtech
- Product numberAT8434
- Product description 99.00%
- Packaging100G
- Price$820
- Updated2026-05-21
- Buy
- ManufacturerAccelPharmtech
- Product numberAT8434
- Product description 99.00%
- Packaging25G
- Price$290
- Updated2026-05-21
- Buy
- ManufacturerAccelPharmtech
- Product numberAT8434
- Product descriptionNilotinib 99.00%
- Packaging10G
- Price$180
- Updated2021-12-16
- Buy
- ManufacturerAccelPharmtech
- Product numberAT8434
- Product description 99.00%
- Packaging10G
- Price$180
- Updated2026-05-21
- Buy
- ManufacturerACHEMBLOCK
- Product numberX193239
- Product description4-Methyl-N-[3-(4-methyl-1-imidazolyl)-5-(trifluoromethyl)phenyl]-3-[[4-(3-pyridyl)-2-pyrimidyl]amino]benzamide 98.0%
- Packaging5G
- Price$420
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberX193239
- Product description4-Methyl-N-[3-(4-methyl-1-imidazolyl)-5-(trifluoromethyl)phenyl]-3-[[4-(3-pyridyl)-2-pyrimidyl]amino]benzamide 98.0%
- Packaging1G
- Price$110
- Updated2026-05-27
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1057-M005
- Product descriptionNilotinib ≥95%
- Packaging5mg
- Price$76
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA0036TM | 4-Methyl-3-((4-(3-pyridinyl)-2-pyrimidinyl)amino)-N-(5-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)phenyl)benzamide 98% | 1mg | $10 | 2026-05-28 | Buy |
| aablocks | AA0036TM | 4-Methyl-3-((4-(3-pyridinyl)-2-pyrimidinyl)amino)-N-(5-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)phenyl)benzamide ≥99% | 25mg | $10 | 2026-05-28 | Buy |
| aablocks | AA0036TM | 4-Methyl-3-((4-(3-pyridinyl)-2-pyrimidinyl)amino)-N-(5-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)phenyl)benzamide 98% | 100mg | $23 | 2026-05-28 | Buy |
| aablocks | AA0036TM | 4-Methyl-3-((4-(3-pyridinyl)-2-pyrimidinyl)amino)-N-(5-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)phenyl)benzamide 98% | 250mg | $27 | 2026-05-28 | Buy |
| aablocks | AA0036TM | 4-Methyl-3-((4-(3-pyridinyl)-2-pyrimidinyl)amino)-N-(5-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)phenyl)benzamide 98% | 1g | $68 | 2026-05-28 | Buy |
| aablocks | AA0036TM | 4-Methyl-3-((4-(3-pyridinyl)-2-pyrimidinyl)amino)-N-(5-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)phenyl)benzamide 98% | 5g | $196 | 2026-05-28 | Buy |
| aablocks | AA0036TM | 4-Methyl-3-((4-(3-pyridinyl)-2-pyrimidinyl)amino)-N-(5-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)phenyl)benzamide 98% | 10g | $246 | 2026-05-28 | Buy |
| aablocks | AA0036TM | 4-Methyl-3-((4-(3-pyridinyl)-2-pyrimidinyl)amino)-N-(5-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)phenyl)benzamide 98% | 25g | $540 | 2026-05-28 | Buy |
| aablocks | AA0036TM | 4-Methyl-3-((4-(3-pyridinyl)-2-pyrimidinyl)amino)-N-(5-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)phenyl)benzamide 98% | 100g | $1430 | 2026-05-28 | Buy |
| AccelPharmtech | AT8434 | 99.00% | 100G | $820 | 2026-05-21 | Buy |
| AccelPharmtech | AT8434 | 99.00% | 25G | $290 | 2026-05-21 | Buy |
| AccelPharmtech | AT8434 | Nilotinib 99.00% | 10G | $180 | 2021-12-16 | Buy |
| AccelPharmtech | AT8434 | 99.00% | 10G | $180 | 2026-05-21 | Buy |
| ACHEMBLOCK | X193239 | 4-Methyl-N-[3-(4-methyl-1-imidazolyl)-5-(trifluoromethyl)phenyl]-3-[[4-(3-pyridyl)-2-pyrimidyl]amino]benzamide 98.0% | 5G | $420 | 2026-05-27 | Buy |
| ACHEMBLOCK | X193239 | 4-Methyl-N-[3-(4-methyl-1-imidazolyl)-5-(trifluoromethyl)phenyl]-3-[[4-(3-pyridyl)-2-pyrimidyl]amino]benzamide 98.0% | 1G | $110 | 2026-05-27 | Buy |
| Adipogen Life Sciences | SYN-1057-M005 | Nilotinib ≥95% | 5mg | $76 | 2026-05-06 | Buy |
Properties
Melting point :231-233 °C
Density :1.36
storage temp. :-20°C Freezer
solubility :Soluble in DMSO (up to 50 mg/ml)
form :Beige powder.
color :Off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
InChIKey :HHZIURLSWUIHRB-UHFFFAOYSA-N
SMILES :N1(C=C(C)N=C1)C1C=C(C=C(C=1)NC(=O)C1C=CC(C)=C(NC2=NC=CC(C3=CC=CN=C3)=N2)C=1)C(F)(F)F
CAS DataBase Reference :641571-10-0(CAS DataBase Reference)
Density :1.36
storage temp. :-20°C Freezer
solubility :Soluble in DMSO (up to 50 mg/ml)
form :Beige powder.
color :Off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
InChIKey :HHZIURLSWUIHRB-UHFFFAOYSA-N
SMILES :N1(C=C(C)N=C1)C1C=C(C=C(C=1)NC(=O)C1C=CC(C)=C(NC2=NC=CC(C3=CC=CN=C3)=N2)C=1)C(F)(F)F
CAS DataBase Reference :641571-10-0(CAS DataBase Reference)
Safety Information
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Description
Nilotinib is the other second-generation Abl kinase inhibitor approved for treatment of patients with CML. Nilotinib has increased affinity for the Abl kinase compared with imatinib, binding with an improved topologic fit to the kinase site in its inactive form.Nilotinib is active in chronic and accelerated phase CML patients who have developed resistance to imatinib. As with dasatinib, nilotinib was compared with imatinib in a phase III randomized trial as initial therapy for chronic phase CML patients, with nilotinib achieving higher rates of complete cytogenetic and major molecular responses and with fewer cases of disease progression or clonal evolution in the nilotinib-treated cohorts. Survival outcomes were similar in all arms. Common adverse events with nilotinib included rash, gastrointestinal disturbances (nausea, vomiting, diarrhea), neutropenia, and thrombocytopenia. Pleural effusion and peripheral edema are less common than with dasatinib. In addition, QT prolongation and a risk of pancreatitis are serious side effects of nilotinib.More related product prices
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Suppliers and manufacturers
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Nilotinib
CAS:641571-10-0