OC000459
|
- $27 - $3023
- Product name: OC000459
- CAS: 851723-84-7
- MF: C21H17FN2O2
- MW: 348.37
- EINECS:
- MDL Number:MFCD18633254
- Synonyms:OC000459;2-(5-fluoro-2-Methyl-3-(quinolin- 2-ylMethyl)-1H-indol-1-yl)acetic acid;5-Fluoro-2-Methyl-3-quinolin-2-ylMethylindo-1-yl)-acetic(OC000459);[5-Fluoro-2-methyl-3-(quinolin-2-ylmethyl)indol-1-yl]acetic acid;5-Fluoro-2-methyl-3-(2-quinolinylmethyl)-1H-indole-1-acetic acid;OC000495;(5-Fluoro-3-isoquinolin-3-ylMethyl-2-Methyl-indol-1-yl)-acetic acid;[5-Fluoro-2-methyl-3-(quinolin-2-ylmethyl)indol-1-yl]acetic acid OC000459
55 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- ApexBio Technology
- Arctom
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- TRC
- Usbiological
Package
- 200mg
- 250mg
- 1000mg
- 10mM*1mLinDMSO(Solid+Solvent)
- 500mg
- 2g
- 2000mg
- 10mM*1mLinDMSO(Solution)
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 1G
- Manufactureraablocks
- Product numberAA004MU7
- Product descriptionOC000459 98%(HPLC)
- Packaging10mg
- Price$97
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA004MU7
- Product descriptionOC000459 98%(HPLC)
- Packaging25mg
- Price$204
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA004MU7
- Product descriptionOC000459 ≥98%
- Packaging50mg
- Price$348
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA004MU7
- Product descriptionOC000459 ≥98%
- Packaging100mg
- Price$627
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA004MU7
- Product descriptionOC000459 98%(HPLC)
- Packaging5mg
- Price$58
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberL22431
- Product descriptionOC-459 98%
- Packaging25MG
- Price$55
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberL22431
- Product descriptionOC-459 98%
- Packaging1G
- Price$645
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberL22431
- Product descriptionOC-459 98%
- Packaging100MG
- Price$155
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product numberY0372
- Product descriptionOC000459
- Packaging1mg
- Price$27
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberY0372
- Product descriptionOC000459
- Packaging5mg
- Price$55
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1535
- Product descriptionOC000459
- Packaging5mg
- Price$81
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1535
- Product descriptionOC000459
- Packaging10mg
- Price$138
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1535
- Product descriptionOC000459
- Packaging50mg
- Price$498
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberSLK-S2822
- Product descriptionOC000459 99.5%
- Packaging10mg
- Price$352
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-15342
- Product descriptionTimapiprant 98.06%
- Packaging100mg
- Price$466
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberSLK-S2822
- Product descriptionOC000459 99.5%
- Packaging5mg
- Price$257
- Updated2026-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA004MU7 | OC000459 98%(HPLC) | 10mg | $97 | 2026-05-28 | Buy |
| aablocks | AA004MU7 | OC000459 98%(HPLC) | 25mg | $204 | 2026-05-28 | Buy |
| aablocks | AA004MU7 | OC000459 ≥98% | 50mg | $348 | 2026-05-28 | Buy |
| aablocks | AA004MU7 | OC000459 ≥98% | 100mg | $627 | 2026-05-28 | Buy |
| aablocks | AA004MU7 | OC000459 98%(HPLC) | 5mg | $58 | 2026-05-28 | Buy |
| ACHEMBLOCK | L22431 | OC-459 98% | 25MG | $55 | 2026-05-27 | Buy |
| ACHEMBLOCK | L22431 | OC-459 98% | 1G | $645 | 2026-05-27 | Buy |
| ACHEMBLOCK | L22431 | OC-459 98% | 100MG | $155 | 2026-05-27 | Buy |
| AK Scientific | Y0372 | OC000459 | 1mg | $27 | 2021-12-16 | Buy |
| AK Scientific | Y0372 | OC000459 | 5mg | $55 | 2021-12-16 | Buy |
| ApexBio Technology | B1535 | OC000459 | 5mg | $81 | 2021-12-16 | Buy |
| ApexBio Technology | B1535 | OC000459 | 10mg | $138 | 2021-12-16 | Buy |
| ApexBio Technology | B1535 | OC000459 | 50mg | $498 | 2021-12-16 | Buy |
| Arctom | SLK-S2822 | OC000459 99.5% | 10mg | $352 | 2026-05-26 | Buy |
| Arctom | HY-15342 | Timapiprant 98.06% | 100mg | $466 | 2026-05-26 | Buy |
| Arctom | SLK-S2822 | OC000459 99.5% | 5mg | $257 | 2026-05-26 | Buy |
Properties
Boiling point :574.4±50.0 °C(Predicted)
Density :1.29
storage temp. :Store at -20°C
solubility :DMF: 0.5 mg/ml; DMSO: 1.1 mg/ml; DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml
form :A crystalline solid
pka :4.08±0.10(Predicted)
color :Light yellow to yellow
Density :1.29
storage temp. :Store at -20°C
solubility :DMF: 0.5 mg/ml; DMSO: 1.1 mg/ml; DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml
form :A crystalline solid
pka :4.08±0.10(Predicted)
color :Light yellow to yellow
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||
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Description
OC000459 is a potent, selective DP2 antagonist that displaces [3H]prostaglandin D2 ([3H]PGD2) from human recombinant DP2 receptors (Ki = 13 nM), rat recombinant DP2 receptors (Ki = 3 nM), and human native DP2 (Ki = 4 nM; Th2 cell membranes) without interfering with the ligand binding properties of other prostanoid receptors, including PGE1–4, DP1, TP, PGI2, and PGF. OC000459 inhibits chemotaxis and cytokine production of human Th2 lymphocytes with IC50 values of 28 and 19 nM, respectively, and competitively antagonizes eosinophil shape change responses induced by PGD2 in both isolated human leukocytes (pKB = 7.9) and human whole blood (pKB = 7.5). OC000459 was shown to inhibit blood eosinophilia in rats induced by 13,14-dihydro-15-keto PGD2 (ED50 = 0.04 mg/kg) and airway eosinophilia in guinea pigs in response to an aerosol of 13,14-dihydro-15-keto PGD2 (ED50 = 0.01 mg/kg).Related product price
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Suppliers and manufacturers
Wuhan Nutra Biotechnology Co.,Ltd
ATK CHEMICAL COMPANY LIMITED
TargetMol Chemicals Inc.
Dideu Industries Group Limited
BOC Sciences
Zhejiang J&C Biological Technology Co.,Limited
Guangzhou TongYi biochemistry technology Co.,LTD
Labnetwork lnc.
InvivoChem
OC000459
CAS:851723-84-7