ONO-AE3-208
|
- $18 - $2958
- Product name: ONO-AE3-208
- CAS: 402473-54-5
- MF: C24H21FN2O3
- MW: 404.43
- EINECS:
- MDL Number:MFCD13184814
- Synonyms:4-Cyano-2-[[2-(4-fluoro-1-naphthalenyl)-1-oxopropyl]amino]Benzenebutanoic acid;ONO-AE3-208;AE 3-208;ONO-AE3-208;AE 3-208;ONO AE3 208;AE 3-208;ONO AE3 208;Benzenebutanoic acid, 4-cyano-2-[[2-(4-fluoro-1-naphthalenyl)-1-oxopropyl]amino]-;4-(4-cyano-2-(2-(4-fluoronaphthalen-1-yl)propanamido)phenyl)butanoic acid;4-{4-Cyano-2-[2-(4-fluoro-naphthalen-1-yl)-propionylamino]-phenyl}-butyric acid
74 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 10
- 10mM*1mLinDMSO(Solid+Solvent)
- 10mM*1mLinDMSO(Solution)
- 1mg
- 2mg
- 50
- 2.5mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100MG
- 250mg
- 1G
- Manufactureraablocks
- Product numberAA00C0UD
- Product description4-Cyano-2-[[2-(4-fluoro-1-naphthalenyl)-1-oxopropyl]amino]benzenebutanoic acid 98%
- Packaging1mg
- Price$18
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00C0UD
- Product description4-Cyano-2-[[2-(4-fluoro-1-naphthalenyl)-1-oxopropyl]amino]benzenebutanoic acid 98%
- Packaging2mg
- Price$24
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00C0UD
- Product description4-Cyano-2-[[2-(4-fluoro-1-naphthalenyl)-1-oxopropyl]amino]benzenebutanoic acid 98%
- Packaging5mg
- Price$35
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00C0UD
- Product description4-Cyano-2-[[2-(4-fluoro-1-naphthalenyl)-1-oxopropyl]amino]benzenebutanoic acid ≥98%
- Packaging10mg
- Price$68
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00C0UD
- Product description4-Cyano-2-[[2-(4-fluoro-1-naphthalenyl)-1-oxopropyl]amino]benzenebutanoic acid
- Packaging25mg
- Price$148
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00C0UD
- Product description4-Cyano-2-[[2-(4-fluoro-1-naphthalenyl)-1-oxopropyl]amino]benzenebutanoic acid
- Packaging50mg
- Price$208
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberS87321
- Product descriptionONO-AE3-208 98%
- Packaging100MG
- Price$400
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberS87321
- Product descriptionONO-AE3-208 98%
- Packaging100MG
- Price$400
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberS87321
- Product descriptionONO-AE3-208 98%
- Packaging1G
- Price$1995
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberS87321
- Product descriptionONO-AE3-208 98%
- Packaging1G
- Price$1995
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number3952AH
- Product description4-(4-Cyano-2-(2-(4-fluoronaphthalen-1-yl)propanamido)phenyl)butanoicacid
- Packaging10mg
- Price$284
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA187661
- Product descriptionONO-AE3-208 98+%
- Packaging50mg
- Price$537
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA187661
- Product descriptionONO-AE3-208 98+%
- Packaging100mg
- Price$755
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA187661
- Product descriptionONO-AE3-208 98+%
- Packaging250mg
- Price$1129
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA187661
- Product descriptionONO-AE3-208 98+%
- Packaging5mg
- Price$82
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA187661
- Product descriptionONO-AE3-208 98+%
- Packaging2mg
- Price$63
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00C0UD | 4-Cyano-2-[[2-(4-fluoro-1-naphthalenyl)-1-oxopropyl]amino]benzenebutanoic acid 98% | 1mg | $18 | 2026-05-28 | Buy |
| aablocks | AA00C0UD | 4-Cyano-2-[[2-(4-fluoro-1-naphthalenyl)-1-oxopropyl]amino]benzenebutanoic acid 98% | 2mg | $24 | 2026-05-28 | Buy |
| aablocks | AA00C0UD | 4-Cyano-2-[[2-(4-fluoro-1-naphthalenyl)-1-oxopropyl]amino]benzenebutanoic acid 98% | 5mg | $35 | 2026-05-28 | Buy |
| aablocks | AA00C0UD | 4-Cyano-2-[[2-(4-fluoro-1-naphthalenyl)-1-oxopropyl]amino]benzenebutanoic acid ≥98% | 10mg | $68 | 2026-05-28 | Buy |
| aablocks | AA00C0UD | 4-Cyano-2-[[2-(4-fluoro-1-naphthalenyl)-1-oxopropyl]amino]benzenebutanoic acid | 25mg | $148 | 2026-05-28 | Buy |
| aablocks | AA00C0UD | 4-Cyano-2-[[2-(4-fluoro-1-naphthalenyl)-1-oxopropyl]amino]benzenebutanoic acid | 50mg | $208 | 2026-05-28 | Buy |
| ACHEMBLOCK | S87321 | ONO-AE3-208 98% | 100MG | $400 | 2026-05-25 | Buy |
| ACHEMBLOCK | S87321 | ONO-AE3-208 98% | 100MG | $400 | 2026-05-27 | Buy |
| ACHEMBLOCK | S87321 | ONO-AE3-208 98% | 1G | $1995 | 2026-05-25 | Buy |
| ACHEMBLOCK | S87321 | ONO-AE3-208 98% | 1G | $1995 | 2026-05-27 | Buy |
| AK Scientific | 3952AH | 4-(4-Cyano-2-(2-(4-fluoronaphthalen-1-yl)propanamido)phenyl)butanoicacid | 10mg | $284 | 2021-12-16 | Buy |
| Ambeed | A187661 | ONO-AE3-208 98+% | 50mg | $537 | 2021-12-16 | Buy |
| Ambeed | A187661 | ONO-AE3-208 98+% | 100mg | $755 | 2021-12-16 | Buy |
| Ambeed | A187661 | ONO-AE3-208 98+% | 250mg | $1129 | 2021-12-16 | Buy |
| Ambeed | A187661 | ONO-AE3-208 98+% | 5mg | $82 | 2021-12-16 | Buy |
| Ambeed | A187661 | ONO-AE3-208 98+% | 2mg | $63 | 2021-12-16 | Buy |
Properties
Boiling point :662.4±55.0 °C(Predicted)
Density :1.30
storage temp. :-20°C
solubility :≥40.4 mg/mL in DMSO with gentle warming; insoluble in H2O; ≥8.1 mg/mL in EtOH with gentle warming and ultrasonic
pka :4.69±0.10(Predicted)
form :powder
color :white to beige
InChI :InChI=1S/C24H21FN2O3/c1-15(18-11-12-21(25)20-7-3-2-6-19(18)20)24(30)27-22-13-16(14-26)9-10-17(22)5-4-8-23(28)29/h2-3,6-7,9-13,15H,4-5,8H2,1H3,(H,27,30)(H,28,29)
InChIKey :MTDIMKNAJUQTIO-UHFFFAOYSA-N
SMILES :C1(CCCC(O)=O)=CC=C(C#N)C=C1NC(=O)C(C1=C2C(C=CC=C2)=C(F)C=C1)C
Density :1.30
storage temp. :-20°C
solubility :≥40.4 mg/mL in DMSO with gentle warming; insoluble in H2O; ≥8.1 mg/mL in EtOH with gentle warming and ultrasonic
pka :4.69±0.10(Predicted)
form :powder
color :white to beige
InChI :InChI=1S/C24H21FN2O3/c1-15(18-11-12-21(25)20-7-3-2-6-19(18)20)24(30)27-22-13-16(14-26)9-10-17(22)5-4-8-23(28)29/h2-3,6-7,9-13,15H,4-5,8H2,1H3,(H,27,30)(H,28,29)
InChIKey :MTDIMKNAJUQTIO-UHFFFAOYSA-N
SMILES :C1(CCCC(O)=O)=CC=C(C#N)C=C1NC(=O)C(C1=C2C(C=CC=C2)=C(F)C=C1)C
Safety Information
| Symbol(GHS): | ||||||||
|---|---|---|---|---|---|---|---|---|
| Signal word: | ||||||||
| Hazard statements: |
|
|||||||
| Precautionary statements: |
|
Description
ONO-AE3-208 is an antagonist of the EP4 receptor (Ki = 1.3 nM) which less potently affects EP3, FP, and TP receptors (Kis = 30, 790, and 2,400 nM, respectively) and is without effect on other prostanoid receptors. In wild type mice, it mimics deletion of EP4 by producing severe colitis, with epithelial loss, crypt damage, and inflammation, after treatment with 3% dextran sodium sulfate. ONO-AE3-208 has also been used to implicate EP4 signaling in immune and autoimmune responses, inflammation, and cancer.More related product prices
L-161,982 CJ-42794 GW 627368X CJ 033466 ETHYL 2-CYANOACRYLATE Sodium cyanoborohydride Sulfanilic acid GrapiprantRelated product price
-
L-161,982
$37-1309 -
CJ-42794
$20-3998 -
GW 627368X
$10-2500
