Obeticholic Acid
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- $5 - $1872
- Product name: Obeticholic Acid
- CAS: 459789-99-2
- MF: C26H44O4
- MW: 420.63
- EINECS:810-245-2
- MDL Number:MFCD16621104
- Synonyms:6alpha-Ethyl-chenodeoxycholic acid;6-Ecdca;6alph;6-Ethyl-cdca;C15636;6-Ethylchenodeoxycholic acid(Obeticholic Acid);Obeticholic Acid;(3α,5β,6α,7α)-6-ethyl-3,7-dihydroxy-cholan-24-oic acid
86 prices
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Brand
- aablocks
- ACHEMBLOCK
- Adipogen Life Sciences
- AK Scientific
- ApexBio Technology
- Arctom
- Atlantic Research Chemicals
- AvaChem
- Axon Medchem
- Biorbyt Ltd
- Cayman Chemical
- ChemScene
- DC Chemicals
- Matrix Scientific
- Sigma-Aldrich
- TRC
Package
- 10mM(1mLinDMSO)
- 50mg
- 200mg
- 1.00g
- 1mlx10mM(inDMSO)
- 10mg
- 5.00g
- 10.00g
- 10mM*1mLinDMSO
- 10mM*1mLinDMSO(Solution)
- 5mg
- 25mg
- 100mg
- 250mg
- 500mg
- 1g
- 5g
- 10mM(in1mLDMSO)
- 10mM*1mLinDMSO(Solid+Solvent)
- Manufactureraablocks
- Product numberAA00365Z
- Product description(R)-4-((3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid 98%
- Packaging100mg
- Price$5
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00365Z
- Product description(R)-4-((3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid 98%
- Packaging250mg
- Price$10
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00365Z
- Product description(R)-4-((3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid 98%
- Packaging500mg
- Price$18
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00365Z
- Product description(R)-4-((3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid 98%
- Packaging1g
- Price$26
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00365Z
- Product description(R)-4-((3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid 98%
- Packaging5g
- Price$88
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberH-8877
- Product description6-ECDCA 98%
- Packaging5G
- Price$120
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberH-8877
- Product description6-ECDCA 98%
- Packaging1G
- Price$35
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberH-8877
- Product description6-ECDCA 98%
- Packaging100MG
- Price$5
- Updated2026-05-27
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3560-M005
- Product description6-ECDCA ≥95%(NMR)
- Packaging5mg
- Price$20
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3560-M025
- Product description6-ECDCA ≥95%(NMR)
- Packaging25mg
- Price$80
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3560-M025
- Product description6-ECDCA ≥95%(NMR)
- Packaging25mg
- Price$200
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3560-M100
- Product description6-ECDCA ≥95%(NMR)
- Packaging100mg
- Price$200
- Updated2026-05-06
- Buy
- ManufacturerAK Scientific
- Product numberY1328
- Product descriptionINT-747
- Packaging100mg
- Price$290
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4888
- Product descriptionObeticholic Acid
- Packaging100mg
- Price$220
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB4888
- Product descriptionObeticholicAcid
- Packaging100mg
- Price$470
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4888
- Product descriptionObeticholicAcid
- Packaging25mg
- Price$200
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00365Z | (R)-4-((3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid 98% | 100mg | $5 | 2026-05-28 | Buy |
| aablocks | AA00365Z | (R)-4-((3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid 98% | 250mg | $10 | 2026-05-28 | Buy |
| aablocks | AA00365Z | (R)-4-((3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid 98% | 500mg | $18 | 2026-05-28 | Buy |
| aablocks | AA00365Z | (R)-4-((3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid 98% | 1g | $26 | 2026-05-28 | Buy |
| aablocks | AA00365Z | (R)-4-((3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid 98% | 5g | $88 | 2026-05-28 | Buy |
| ACHEMBLOCK | H-8877 | 6-ECDCA 98% | 5G | $120 | 2026-05-27 | Buy |
| ACHEMBLOCK | H-8877 | 6-ECDCA 98% | 1G | $35 | 2026-05-27 | Buy |
| ACHEMBLOCK | H-8877 | 6-ECDCA 98% | 100MG | $5 | 2026-05-27 | Buy |
| Adipogen Life Sciences | AG-CR1-3560-M005 | 6-ECDCA ≥95%(NMR) | 5mg | $20 | 2026-05-06 | Buy |
| Adipogen Life Sciences | AG-CR1-3560-M025 | 6-ECDCA ≥95%(NMR) | 25mg | $80 | 2026-05-06 | Buy |
| Adipogen Life Sciences | AG-CR1-3560-M025 | 6-ECDCA ≥95%(NMR) | 25mg | $200 | 2021-12-16 | Buy |
| Adipogen Life Sciences | AG-CR1-3560-M100 | 6-ECDCA ≥95%(NMR) | 100mg | $200 | 2026-05-06 | Buy |
| AK Scientific | Y1328 | INT-747 | 100mg | $290 | 2021-12-16 | Buy |
| ApexBio Technology | B4888 | Obeticholic Acid | 100mg | $220 | 2026-05-06 | Buy |
| ApexBio Technology | B4888 | ObeticholicAcid | 100mg | $470 | 2021-12-16 | Buy |
| ApexBio Technology | B4888 | ObeticholicAcid | 25mg | $200 | 2021-12-16 | Buy |
Properties
Melting point :108-110 °C
Boiling point :562.9±25.0 °C(Predicted)
Density :1.091
storage temp. :-20°C
solubility :Soluble in DMSO (up to 35 mg/ml) or in Ethanol (up to 25 mg/ml)
form :White solid.
pka :4.76±0.10(Predicted)
color :White
optical activity :[α]/D +4 to +6°, c =1.0 in methanol
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
InChIKey :ZXERDUOLZKYMJM-IMGBAYNYNA-N
SMILES :C[C@]12CC[C@@H](O)C[C@@]1([H])[C@@H](CC)[C@@H](O)[C@@]1([H])[C@]3([H])CC[C@]([H])([C@H](C)CCC(=O)O)[C@@]3(C)CC[C@]21[H] |&1:1,4,7,9,12,14,16,20,22,29,33,r|
Boiling point :562.9±25.0 °C(Predicted)
Density :1.091
storage temp. :-20°C
solubility :Soluble in DMSO (up to 35 mg/ml) or in Ethanol (up to 25 mg/ml)
form :White solid.
pka :4.76±0.10(Predicted)
color :White
optical activity :[α]/D +4 to +6°, c =1.0 in methanol
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
InChIKey :ZXERDUOLZKYMJM-IMGBAYNYNA-N
SMILES :C[C@]12CC[C@@H](O)C[C@@]1([H])[C@@H](CC)[C@@H](O)[C@@]1([H])[C@]3([H])CC[C@]([H])([C@H](C)CCC(=O)O)[C@@]3(C)CC[C@]21[H] |&1:1,4,7,9,12,14,16,20,22,29,33,r|
Safety Information
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| Signal word: | Warning | ||||||||||||||||||||||||||||
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Description
Obeticholic acid is a potent and selective farnesoid X receptor agonist that promotes the flow of bile in the liver. The drug was approved by the USFDA for the treatment of the rare chronic liver disease primary biliary cholangitis (PBC) in combination with ursodeoxycholic acid (UDCA) in adults with inadequate response to UDCA or as a single agent therapy in adults unable to tolerate UDCA. Obeticholic acid was discovered at the Università de Perugia and developed by Intercept Pharmaceuticals. Obeticholic acid has also been granted orphan drug designation for the treatment of primary sclerosing cholangitis and primary biliary cirrhosis and has received breakthrough therapy designation for the treatment of patients with nonalcohol steatohepatitis (NASH) with liver fibrosis.Suppliers and manufacturers
BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.
Obeticholic Acid
CAS:459789-99-2
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Nanjing ChemLin Chemical Industry Co., Ltd.
Obeticholic Acid
CAS:459789-99-2