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ChemicalBook >> CAS DataBase List >> Palifosfamide

Palifosfamide

Palifosfamide price.
  • $33 - $6980
  • Product name: Palifosfamide
  • CAS: 31645-39-3
  • MF: C4H11Cl2N2O2P
  • MW: 221.02
  • EINECS:
  • MDL Number:MFCD01705455
  • Synonyms:Ifosforamide mustard;N,N'-Di-(2-chloroethyl)phosphorodiamidic acid;N,N'-BIS(2-CHLOROETHYL)PHOSPHORODIAMIDATE;Isophosphamide mustard ;palifosfamide;N,N'-Bis(2-chloroethyl)phosphorodiamidic acid;N1,N2-Bis(2-chloroethyl)phosphoric acid diamide;Nsc 297900
59 prices
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  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
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  • ChemScene
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  • Manufactureraablocks
  • Product numberAA000ZGV
  • Product descriptionPalifosfamide ≥95%
  • Packaging10mg
  • Price$37
  • Updated2026-05-25
  • Buy
  • Manufactureraablocks
  • Product numberAA000ZGV
  • Product descriptionPalifosfamide ≥95%
  • Packaging25mg
  • Price$81
  • Updated2026-05-25
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  • Manufactureraablocks
  • Product numberAA000ZGV
  • Product descriptionPalifosfamide 98+%
  • Packaging1mg
  • Price$36
  • Updated2026-05-25
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  • Manufactureraablocks
  • Product numberAA000ZGV
  • Product descriptionPalifosfamide ≥95%
  • Packaging50mg
  • Price$124
  • Updated2026-05-25
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  • Manufactureraablocks
  • Product numberAA000ZGV
  • Product descriptionPalifosfamide ≥95%
  • Packaging100mg
  • Price$194
  • Updated2026-05-25
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberO33942
  • Product descriptionPalifosfamide 98%
  • Packaging1G
  • Price$6210
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberO33942
  • Product descriptionPalifosfamide 98%
  • Packaging100MG
  • Price$1035
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberO33942
  • Product descriptionPalifosfamide 98%
  • Packaging25MG
  • Price$540
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product number7291CA
  • Product descriptionPalifosfamide
  • Packaging25mg
  • Price$179
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number7291CA
  • Product descriptionPalifosfamide
  • Packaging100mg
  • Price$293
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0005271
  • Product descriptionPALIFOSFAMIDE 95.00%
  • Packaging5MG
  • Price$502.7
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberA3696
  • Product descriptionPalifosfamide
  • Packaging200mg
  • Price$1680
  • Updated2026-05-06
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  • ManufacturerApexBio Technology
  • Product numberA3696
  • Product descriptionPalifosfamide
  • Packaging50mg
  • Price$600
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3696
  • Product descriptionPalifosfamide
  • Packaging10mg
  • Price$335
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3696
  • Product descriptionPalifosfamide
  • Packaging5mg
  • Price$232
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3696
  • Product descriptionPalifosfamide
  • Packaging10mg
  • Price$210
  • Updated2026-05-06
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA000ZGV Palifosfamide ≥95% 10mg $37 2026-05-25 Buy
aablocks AA000ZGV Palifosfamide ≥95% 25mg $81 2026-05-25 Buy
aablocks AA000ZGV Palifosfamide 98+% 1mg $36 2026-05-25 Buy
aablocks AA000ZGV Palifosfamide ≥95% 50mg $124 2026-05-25 Buy
aablocks AA000ZGV Palifosfamide ≥95% 100mg $194 2026-05-25 Buy
ACHEMBLOCK O33942 Palifosfamide 98% 1G $6210 2026-05-27 Buy
ACHEMBLOCK O33942 Palifosfamide 98% 100MG $1035 2026-05-27 Buy
ACHEMBLOCK O33942 Palifosfamide 98% 25MG $540 2026-05-27 Buy
AK Scientific 7291CA Palifosfamide 25mg $179 2021-12-16 Buy
AK Scientific 7291CA Palifosfamide 100mg $293 2021-12-16 Buy
American Custom Chemicals Corporation API0005271 PALIFOSFAMIDE 95.00% 5MG $502.7 2021-12-16 Buy
ApexBio Technology A3696 Palifosfamide 200mg $1680 2026-05-06 Buy
ApexBio Technology A3696 Palifosfamide 50mg $600 2026-05-06 Buy
ApexBio Technology A3696 Palifosfamide 10mg $335 2021-12-16 Buy
ApexBio Technology A3696 Palifosfamide 5mg $232 2021-12-16 Buy
ApexBio Technology A3696 Palifosfamide 10mg $210 2026-05-06 Buy

Properties

Melting point :106-107 ºC
Boiling point :341.5±52.0 °C(Predicted)
Density :1.411
storage temp. :Store at -20°C, protect from light, stored under nitrogen
solubility :≥22.1 mg/mL in DMSO; insoluble in EtOH; ≥19.4 mg/mL in H2O with gentle warming and ultrasonic
form :Powder
pka :0.79±0.50(Predicted)
color :White to off-white
InChI :InChI=1S/C4H11Cl2N2O2P/c5-1-3-7-11(9,10)8-4-2-6/h1-4H2,(H3,7,8,9,10)
InChIKey :BKCJZNIZRWYHBN-UHFFFAOYSA-N
SMILES :P(NCCCl)(NCCCl)(O)=O
CAS DataBase Reference :31645-39-3

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Palifosfamide is an active metabolite of the DNA alkylating agent ifosfamide. It is formed through hydroxylation of ifosfamide by various hepatic cytochrome P450 (CYP) isoforms. It is cytotoxic to L1210 and CCRF-CEM cancer cells when used at a concentration of 100 μM. Palifosfamide (100 mg/kg per day) reduces tumor growth in murine Lewis lung carcinoma and L1210 leukemia models, as well as a rat Yoshida ascitic sarcoma model.

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