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ChemicalBook >> CAS DataBase List >> Phenformin hydrochloride

Phenformin hydrochloride

Phenformin hydrochloride price.
  • $18 - $2885
  • Product name: Phenformin hydrochloride
  • CAS: 834-28-6
  • MF: C10H16ClN5
  • MW: 241.72
  • EINECS:212-637-3
  • MDL Number:MFCD00035039
  • Synonyms:1-(diaminomethylene)-2-phenethylguanidine hydrochloride;1-(diaminomethylene)-2-phenethyl-guanidine hydrochloride;1-(diaminomethylidene)-2-phenethylguanidine hydrochloride;1-(diaminomethylidene)-2-phenethyl-guanidine hydrochloride;1-Fenetilbiguanide cloridrato [Italian];1-Phen;meltrol ;n-(2-phenylethyl)-imidodicarbonimidicdiamidmonohydrochloride
49 prices
Selected condition:
Brand
  • aablocks
  • AHH
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Biosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TRC
  • Usbiological
Package
  • 10mM*1mLinDMSO(Solution)
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 500mg
  • 1g
  • 5g
  • 10g
  • 100g
  • 250g
  • 500g
  • 25g
  • 50g
  • 10mM(in 1mL DMSO)
  • Manufactureraablocks
  • Product numberAA00ID7X
  • Product descriptionPhenformin hydrochloride 95%
  • Packaging1g
  • Price$18
  • Updated2026-05-29
  • Buy
  • Manufactureraablocks
  • Product numberAA00ID7X
  • Product descriptionPhenformin hydrochloride 95%
  • Packaging5g
  • Price$40
  • Updated2026-05-29
  • Buy
  • Manufactureraablocks
  • Product numberAA00ID7X
  • Product descriptionPhenformin hydrochloride 95%
  • Packaging25g
  • Price$113
  • Updated2026-05-29
  • Buy
  • ManufacturerAHH
  • Product numberMT-57838
  • Product descriptionPhenformin hydrochloride 98%
  • Packaging250g
  • Price$490
  • Updated2021-12-16
  • Buy
  • ManufacturerAHH
  • Product numberMT-57838
  • Product descriptionPhenformin hydrochloride 97%
  • Packaging250g
  • Price$490
  • Updated2026-05-25
  • Buy
  • ManufacturerAHH
  • Product numberMT-57838
  • Product descriptionPhenformin hydrochloride 97%
  • Packaging250g
  • Price$490
  • Updated2026-05-26
  • Buy
  • ManufacturerAK Scientific
  • Product numberA624
  • Product descriptionPhenformin hydrochloride 98%(HPLC)
  • Packaging5g
  • Price$54
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberA624
  • Product descriptionPhenformin hydrochloride 98%(HPLC)
  • Packaging1g
  • Price$27
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberA624
  • Product descriptionPhenformin hydrochloride
  • Packaging25g
  • Price$54
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0025906
  • Product descriptionPHENFORMIN HYDROCHLORIDE 95.00%
  • Packaging1G
  • Price$126
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1373
  • Product descriptionPhenforminHCl
  • Packaging50g
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1373
  • Product descriptionPhenforminHCl
  • Packaging10mM(in 1mL DMSO)
  • Price$80
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1373
  • Product descriptionPhenforminHCl
  • Packaging10g
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1373
  • Product descriptionPhenformin HCl
  • Packaging5g
  • Price$75
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1373
  • Product descriptionPhenforminHCl
  • Packaging50mg
  • Price$40
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberHY-16397A
  • Product descriptionPhenforminhydrochloride 99.64%
  • Packaging500mg
  • Price$34
  • Updated2026-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00ID7X Phenformin hydrochloride 95% 1g $18 2026-05-29 Buy
aablocks AA00ID7X Phenformin hydrochloride 95% 5g $40 2026-05-29 Buy
aablocks AA00ID7X Phenformin hydrochloride 95% 25g $113 2026-05-29 Buy
AHH MT-57838 Phenformin hydrochloride 98% 250g $490 2021-12-16 Buy
AHH MT-57838 Phenformin hydrochloride 97% 250g $490 2026-05-25 Buy
AHH MT-57838 Phenformin hydrochloride 97% 250g $490 2026-05-26 Buy
AK Scientific A624 Phenformin hydrochloride 98%(HPLC) 5g $54 2026-06-04 Buy
AK Scientific A624 Phenformin hydrochloride 98%(HPLC) 1g $27 2026-06-04 Buy
AK Scientific A624 Phenformin hydrochloride 25g $54 2021-12-16 Buy
American Custom Chemicals Corporation API0025906 PHENFORMIN HYDROCHLORIDE 95.00% 1G $126 2021-12-16 Buy
ApexBio Technology B1373 PhenforminHCl 50g $150 2021-12-16 Buy
ApexBio Technology B1373 PhenforminHCl 10mM(in 1mL DMSO) $80 2021-12-16 Buy
ApexBio Technology B1373 PhenforminHCl 10g $50 2021-12-16 Buy
ApexBio Technology B1373 Phenformin HCl 5g $75 2026-05-06 Buy
ApexBio Technology B1373 PhenforminHCl 50mg $40 2021-12-16 Buy
Arctom HY-16397A Phenforminhydrochloride 99.64% 500mg $34 2026-05-26 Buy

Properties

Melting point :175-178°C
storage temp. :Keep in dark place,Inert atmosphere,2-8°C
solubility :Methanol (Slightly), Water (Slightly)
form :Solid
color :White to Off-White
Water Solubility :>=10 g/100 mL at 21 ºC
InChI :InChI=1S/C10H15N5.ClH/c11-9(12)15-10(13)14-7-6-8-4-2-1-3-5-8;/h1-5H,6-7H2,(H6,11,12,13,14,15);1H
InChIKey :YSUCWSWKRIOILX-UHFFFAOYSA-N
SMILES :N=C(NCCC1C=CC=CC=1)NC(=N)N.[H]Cl
CAS DataBase Reference :834-28-6(CAS DataBase Reference)
EPA Substance Registry System :Phenformin hydrochloride (834-28-6)

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Phenformin is an orally administered biguanide derivative with potential to lower blood glucose concentrations in patients with non-insulin-dependent diabetes mellitus. In general, biguanides improve insulin sensitivity and decrease insulin resistance by inhibiting complex 1 of the mitochondrial respiratory chain and inducing AMP-activated protein kinase (AMPK)-dependent signaling. Phenformin, however, has been withdrawn from clinical use because it also inhibits peripheral glucose oxidation and has an associated effect of inducing lactic acidosis when not metabolized sufficiently. Through AMPK activation, phenformin at 300 mg/kg exhibits anticancer activity by inhibiting the growth of MCF-7 and MDAMB231 breast cancer cell xenografts in mice.

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