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ChemicalBook >> CAS DataBase List >> Pimodivir

Pimodivir

Pimodivir price.
  • $45 - $2700
  • Product name: Pimodivir
  • CAS: 1629869-44-8
  • MF: C20H19F2N5O2
  • MW: 399.39
  • EINECS:
  • MDL Number:MFCD31382121
  • Synonyms:Pimodivir;Pimodivir (VX-787);VRT0928787;VRT-0928787;VX-787; VX 787; VX787; JNJ-872; JNJ 872; JNJ872; VRT-0928787; VRT 0928787; VRT0928787;PIMODIVIR;VX-787 (Pimodivir);Bicyclo[2.2.2]octane-2-carboxylic acid, 3-[[5-fluoro-2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-4-pyrimidinyl]amino]-, (2S,3S)-;(2S,3S)-3-[[5-Fluoro-2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-4-pyrimidinyl]amino]bicyclo[2.2.2]octane-2-carboxylic acid
47 prices
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  • aablocks
  • ACHEMBLOCK
  • AHH
  • ApexBio Technology
  • Arctom
  • Biorbyt Ltd
  • Biosynth
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • TRC
Package
  • 1mL(10mMinDMSO)
  • 1mg
  • 2mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
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  • 1g
  • Manufactureraablocks
  • Product numberAA01EN1K
  • Product description(2S,3S)-3-[[5-Fluoro-2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-4-pyrimidinyl]amino]bicyclo[2.2.2]octane-2-carboxylic acid
  • Packaging1mg
  • Price$45
  • Updated2026-05-30
  • Buy
  • Manufactureraablocks
  • Product numberAA01EN1K
  • Product description(2S,3S)-3-[[5-Fluoro-2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-4-pyrimidinyl]amino]bicyclo[2.2.2]octane-2-carboxylic acid
  • Packaging5mg
  • Price$78
  • Updated2026-05-30
  • Buy
  • Manufactureraablocks
  • Product numberAA01EN1K
  • Product description(2S,3S)-3-[[5-Fluoro-2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-4-pyrimidinyl]amino]bicyclo[2.2.2]octane-2-carboxylic acid
  • Packaging10mg
  • Price$118
  • Updated2026-05-30
  • Buy
  • Manufactureraablocks
  • Product numberAA01EN1K
  • Product description(2S,3S)-3-[[5-Fluoro-2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-4-pyrimidinyl]amino]bicyclo[2.2.2]octane-2-carboxylic acid
  • Packaging25mg
  • Price$199
  • Updated2026-05-30
  • Buy
  • Manufactureraablocks
  • Product numberAA01EN1K
  • Product description(2S,3S)-3-[[5-Fluoro-2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-4-pyrimidinyl]amino]bicyclo[2.2.2]octane-2-carboxylic acid
  • Packaging50mg
  • Price$286
  • Updated2026-05-30
  • Buy
  • Manufactureraablocks
  • Product numberAA01EN1K
  • Product description(2S,3S)-3-[[5-Fluoro-2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-4-pyrimidinyl]amino]bicyclo[2.2.2]octane-2-carboxylic acid
  • Packaging100mg
  • Price$420
  • Updated2026-05-30
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  • ManufacturerACHEMBLOCK
  • Product numberY228290
  • Product descriptionPimodivir 97.00%
  • Packaging100MG
  • Price$595
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberY228290
  • Product descriptionPimodivir 97.00%
  • Packaging25MG
  • Price$265
  • Updated2026-05-27
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  • ManufacturerAHH
  • Product numberAPI-1946
  • Product descriptionVX787 VX787
  • Packaging1g
  • Price$2300
  • Updated2021-12-16
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  • ManufacturerAHH
  • Product numberAPI-1946
  • Product descriptionVX787 97%
  • Packaging1g
  • Price$2300
  • Updated2026-05-26
  • Buy
  • ManufacturerApexBio Technology
  • Product numberBA2005
  • Product descriptionPimodivir
  • Packaging100mg
  • Price$792
  • Updated2026-05-06
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  • ManufacturerApexBio Technology
  • Product numberBA2005
  • Product descriptionPimodivir
  • Packaging50mg
  • Price$459
  • Updated2026-05-06
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  • ManufacturerApexBio Technology
  • Product numberBA2005
  • Product descriptionPimodivir
  • Packaging10mg
  • Price$135
  • Updated2026-05-06
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  • ManufacturerApexBio Technology
  • Product numberBA2005
  • Product descriptionPimodivir
  • Packaging5mg
  • Price$81
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberBA2005
  • Product descriptionPimodivir
  • Packaging1mL(10mMinDMSO)
  • Price$89
  • Updated2026-05-06
  • Buy
  • ManufacturerArctom
  • Product numberHY-12353A
  • Product descriptionPimodivir 99.40%
  • Packaging10mg
  • Price$143
  • Updated2026-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA01EN1K (2S,3S)-3-[[5-Fluoro-2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-4-pyrimidinyl]amino]bicyclo[2.2.2]octane-2-carboxylic acid 1mg $45 2026-05-30 Buy
aablocks AA01EN1K (2S,3S)-3-[[5-Fluoro-2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-4-pyrimidinyl]amino]bicyclo[2.2.2]octane-2-carboxylic acid 5mg $78 2026-05-30 Buy
aablocks AA01EN1K (2S,3S)-3-[[5-Fluoro-2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-4-pyrimidinyl]amino]bicyclo[2.2.2]octane-2-carboxylic acid 10mg $118 2026-05-30 Buy
aablocks AA01EN1K (2S,3S)-3-[[5-Fluoro-2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-4-pyrimidinyl]amino]bicyclo[2.2.2]octane-2-carboxylic acid 25mg $199 2026-05-30 Buy
aablocks AA01EN1K (2S,3S)-3-[[5-Fluoro-2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-4-pyrimidinyl]amino]bicyclo[2.2.2]octane-2-carboxylic acid 50mg $286 2026-05-30 Buy
aablocks AA01EN1K (2S,3S)-3-[[5-Fluoro-2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-4-pyrimidinyl]amino]bicyclo[2.2.2]octane-2-carboxylic acid 100mg $420 2026-05-30 Buy
ACHEMBLOCK Y228290 Pimodivir 97.00% 100MG $595 2026-05-27 Buy
ACHEMBLOCK Y228290 Pimodivir 97.00% 25MG $265 2026-05-27 Buy
AHH API-1946 VX787 VX787 1g $2300 2021-12-16 Buy
AHH API-1946 VX787 97% 1g $2300 2026-05-26 Buy
ApexBio Technology BA2005 Pimodivir 100mg $792 2026-05-06 Buy
ApexBio Technology BA2005 Pimodivir 50mg $459 2026-05-06 Buy
ApexBio Technology BA2005 Pimodivir 10mg $135 2026-05-06 Buy
ApexBio Technology BA2005 Pimodivir 5mg $81 2026-05-06 Buy
ApexBio Technology BA2005 Pimodivir 1mL(10mMinDMSO) $89 2026-05-06 Buy
Arctom HY-12353A Pimodivir 99.40% 10mg $143 2026-05-26 Buy

Properties

Density :1.501±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :Soluble in DMSO, not in water:100.0(Max Conc. mg/mL);250.38(Max Conc. mM)
form :A solid
pka :4.32±0.40(Predicted)
color :White to light yellow
InChIKey :JGPXDNKSIXAZEQ-SBBZOCNPSA-N
SMILES :C12CCC(CC1)[C@H](NC1C(F)=CN=C(C3C4=CC(F)=CN=C4NC=3)N=1)[C@H]2C(O)=O

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Pimodivir is an inhibitor of influenza virus polymerase basic protein 2 (PB2; KD = <0.003 μM). It also binds to glycogen synthase kinase 3β (GSK3β; Ki = ~1.6 μM) and inhibits the activity of Axl and calcium/calmodulin-dependent protein kinase IIβ (CaMKIIβ) by greater than 50% in a panel of 65 human and rat kinases. Pimodivir decreases the replication of seven adamantine- and neuraminidase inhibitor-resistant strains of influenza virus A (EC50s = <0.15-2.8 nM in a cell-based assay). It increases the antiviral activity of oseltamivir , zanamivir , and favipiravir (T-705; ) with 50% combination index (CI50) values of 0.58, 0.64, and 0.89, respectively, in a cell-based assay. Pimodivir increases survival in a mouse model of intranasal influenza A infection when administered at doses of 1, 3, and 10 mg/kg twice per day.

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