Piperine
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- $8 - $1590
- Product name: Piperine
- CAS: 94-62-2
- MF: C17H19NO3
- MW: 285.34
- EINECS:202-348-0
- MDL Number:MFCD00005839
- Synonyms:Piperine,98%;Piperidine, 1-(2E,4E)-5-(1,3-benzodioxol-5-yl)-1-oxo-2,4-pentadienyl-;1-piperinoylpiperidine;PIPERINE(P);PIPERINE(RG);PIPERLINE;Piperine SynonyMs (E,E)-1-[5-(1,3-Benzodioxol-5-yl)-1-oxo-2,4-pentadienyl]-piperidine;Piperine (E,E)-1-[5-(1,3-Benzodioxol-5-yl)-1-oxo-2,4-pentadienyl]-piperidine
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Brand
- A2B
- aablocks
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Package
- 10mg
- 20mg
- 25mg
- 100mg
- 250mg
- 1mlx10mM(inDMSO)
- y0001217
- 200mg
- sample-k
- 1mg
- 50mg
- 10mM(in1mLDMSO)
- 1g
- 1000mg
- 5g
- 10g
- 25g
- 50g
- 100g
- 250g
- 500g
- 1KG
- 1 each
- 1 unit
- 30 mg
- ManufacturerA2B
- Product numberAI62824
- Product description(2E,4E)-5-(1,3-Benzodioxol-5-yl)-1-(1-piperidinyl)-2,4-pentadien-1-one 97%
- Packaging250mg
- Price$9
- Updated2026-05-25
- Buy
- ManufacturerA2B
- Product numberAI62824
- Product description(2E,4E)-5-(1,3-Benzodioxol-5-yl)-1-(1-piperidinyl)-2,4-pentadien-1-one 97%
- Packaging1g
- Price$10
- Updated2026-05-25
- Buy
- ManufacturerA2B
- Product numberAI62824
- Product description(2E,4E)-5-(1,3-Benzodioxol-5-yl)-1-(1-piperidinyl)-2,4-pentadien-1-one 97%
- Packaging5g
- Price$16
- Updated2026-05-25
- Buy
- ManufacturerA2B
- Product numberAI62824
- Product description(2E,4E)-5-(1,3-Benzodioxol-5-yl)-1-(1-piperidinyl)-2,4-pentadien-1-one 97%
- Packaging1mg
- Price$8
- Updated2026-05-25
- Buy
- ManufacturerA2B
- Product numberAI62824
- Product description(2E,4E)-5-(1,3-Benzodioxol-5-yl)-1-(1-piperidinyl)-2,4-pentadien-1-one 97%
- Packaging10g
- Price$27
- Updated2026-05-25
- Buy
- ManufacturerA2B
- Product numberAI62824
- Product description(2E,4E)-5-(1,3-Benzodioxol-5-yl)-1-(1-piperidinyl)-2,4-pentadien-1-one 97%
- Packaging25g
- Price$60
- Updated2026-05-25
- Buy
- ManufacturerA2B
- Product numberAI62824
- Product description(2E,4E)-5-(1,3-Benzodioxol-5-yl)-1-(1-piperidinyl)-2,4-pentadien-1-one 97%
- Packaging100g
- Price$180
- Updated2026-05-25
- Buy
- ManufacturerA2B
- Product numberAI62824
- Product description(2E,4E)-5-(1,3-Benzodioxol-5-yl)-1-(1-piperidinyl)-2,4-pentadien-1-one 97%
- Packaging250g
- Price$358
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA00IHU4
- Product description(2E,4E)-5-(1,3-Benzodioxol-5-yl)-1-(1-piperidinyl)-2,4-pentadien-1-one ≥98%(HPLC)
- Packaging250g
- Price$360
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA00IHU4
- Product description(2E,4E)-5-(1,3-Benzodioxol-5-yl)-1-(1-piperidinyl)-2,4-pentadien-1-one ≥97%
- Packaging100g
- Price$173
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA00IHU4
- Product description(2E,4E)-5-(1,3-Benzodioxol-5-yl)-1-(1-piperidinyl)-2,4-pentadien-1-one 97%
- Packaging1mg
- Price$8
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA00IHU4
- Product description(2E,4E)-5-(1,3-Benzodioxol-5-yl)-1-(1-piperidinyl)-2,4-pentadien-1-one ≥97%
- Packaging5g
- Price$16
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA00IHU4
- Product description(2E,4E)-5-(1,3-Benzodioxol-5-yl)-1-(1-piperidinyl)-2,4-pentadien-1-one ≥97%
- Packaging1g
- Price$10
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA00IHU4
- Product description(2E,4E)-5-(1,3-Benzodioxol-5-yl)-1-(1-piperidinyl)-2,4-pentadien-1-one 97%
- Packaging250mg
- Price$10
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA00IHU4
- Product description(2E,4E)-5-(1,3-Benzodioxol-5-yl)-1-(1-piperidinyl)-2,4-pentadien-1-one 97%
- Packaging10g
- Price$30
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA00IHU4
- Product description(2E,4E)-5-(1,3-Benzodioxol-5-yl)-1-(1-piperidinyl)-2,4-pentadien-1-one ≥97%
- Packaging25g
- Price$54
- Updated2026-05-29
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| A2B | AI62824 | (2E,4E)-5-(1,3-Benzodioxol-5-yl)-1-(1-piperidinyl)-2,4-pentadien-1-one 97% | 250mg | $9 | 2026-05-25 | Buy |
| A2B | AI62824 | (2E,4E)-5-(1,3-Benzodioxol-5-yl)-1-(1-piperidinyl)-2,4-pentadien-1-one 97% | 1g | $10 | 2026-05-25 | Buy |
| A2B | AI62824 | (2E,4E)-5-(1,3-Benzodioxol-5-yl)-1-(1-piperidinyl)-2,4-pentadien-1-one 97% | 5g | $16 | 2026-05-25 | Buy |
| A2B | AI62824 | (2E,4E)-5-(1,3-Benzodioxol-5-yl)-1-(1-piperidinyl)-2,4-pentadien-1-one 97% | 1mg | $8 | 2026-05-25 | Buy |
| A2B | AI62824 | (2E,4E)-5-(1,3-Benzodioxol-5-yl)-1-(1-piperidinyl)-2,4-pentadien-1-one 97% | 10g | $27 | 2026-05-25 | Buy |
| A2B | AI62824 | (2E,4E)-5-(1,3-Benzodioxol-5-yl)-1-(1-piperidinyl)-2,4-pentadien-1-one 97% | 25g | $60 | 2026-05-25 | Buy |
| A2B | AI62824 | (2E,4E)-5-(1,3-Benzodioxol-5-yl)-1-(1-piperidinyl)-2,4-pentadien-1-one 97% | 100g | $180 | 2026-05-25 | Buy |
| A2B | AI62824 | (2E,4E)-5-(1,3-Benzodioxol-5-yl)-1-(1-piperidinyl)-2,4-pentadien-1-one 97% | 250g | $358 | 2026-05-25 | Buy |
| aablocks | AA00IHU4 | (2E,4E)-5-(1,3-Benzodioxol-5-yl)-1-(1-piperidinyl)-2,4-pentadien-1-one ≥98%(HPLC) | 250g | $360 | 2026-05-29 | Buy |
| aablocks | AA00IHU4 | (2E,4E)-5-(1,3-Benzodioxol-5-yl)-1-(1-piperidinyl)-2,4-pentadien-1-one ≥97% | 100g | $173 | 2026-05-29 | Buy |
| aablocks | AA00IHU4 | (2E,4E)-5-(1,3-Benzodioxol-5-yl)-1-(1-piperidinyl)-2,4-pentadien-1-one 97% | 1mg | $8 | 2026-05-29 | Buy |
| aablocks | AA00IHU4 | (2E,4E)-5-(1,3-Benzodioxol-5-yl)-1-(1-piperidinyl)-2,4-pentadien-1-one ≥97% | 5g | $16 | 2026-05-29 | Buy |
| aablocks | AA00IHU4 | (2E,4E)-5-(1,3-Benzodioxol-5-yl)-1-(1-piperidinyl)-2,4-pentadien-1-one ≥97% | 1g | $10 | 2026-05-29 | Buy |
| aablocks | AA00IHU4 | (2E,4E)-5-(1,3-Benzodioxol-5-yl)-1-(1-piperidinyl)-2,4-pentadien-1-one 97% | 250mg | $10 | 2026-05-29 | Buy |
| aablocks | AA00IHU4 | (2E,4E)-5-(1,3-Benzodioxol-5-yl)-1-(1-piperidinyl)-2,4-pentadien-1-one 97% | 10g | $30 | 2026-05-29 | Buy |
| aablocks | AA00IHU4 | (2E,4E)-5-(1,3-Benzodioxol-5-yl)-1-(1-piperidinyl)-2,4-pentadien-1-one ≥97% | 25g | $54 | 2026-05-29 | Buy |
Properties
Melting point :131-135 °C(lit.)
Boiling point :427.77°C (rough estimate)
Density :1.0864 (rough estimate)
refractive index :1.5400 (estimate)
FEMA :2909 | PIPERINE
storage temp. :Sealed in dry,Room Temperature
solubility :Slightly soluble in water, 10% soluble in alcohol, soluble only in certain oils
form :Crystalline Powder
pka :12.22(at 18℃)
color :Off-white to tan or yellow-tan
Odor :at 1.00 % in propylene glycol. pepper animal
Odor Type :spicy
Water Solubility :40 mg/L (18 ºC)
Merck :14,7472
JECFA Number :1600
BRN :90741
Stability :Stable. Incompatible with strong oxidizing agents.
Cosmetics Ingredients Functions :SKIN CONDITIONING - MISCELLANEOUS
InChI :1S/C17H19NO3/c19-17(18-10-4-1-5-11-18)7-3-2-6-14-8-9-15-16(12-14)21-13-20-15/h2-3,6-9,12H,1,4-5,10-11,13H2/b6-2+,7-3+
InChIKey :MXXWOMGUGJBKIW-YPCIICBESA-N
SMILES :O=C(\C=C\C=C\c1ccc2OCOc2c1)N3CCCCC3
LogP :2.66
CAS DataBase Reference :94-62-2(CAS DataBase Reference)
NIST Chemistry Reference :Piperine(94-62-2)
EPA Substance Registry System :2,4-Pentadien-1-one, 5-(1,3-benzodioxol-5-yl)-1-(1-piperidinyl)-, (2E,4E)- (94-62-2)
Boiling point :427.77°C (rough estimate)
Density :1.0864 (rough estimate)
refractive index :1.5400 (estimate)
FEMA :2909 | PIPERINE
storage temp. :Sealed in dry,Room Temperature
solubility :Slightly soluble in water, 10% soluble in alcohol, soluble only in certain oils
form :Crystalline Powder
pka :12.22(at 18℃)
color :Off-white to tan or yellow-tan
Odor :at 1.00 % in propylene glycol. pepper animal
Odor Type :spicy
Water Solubility :40 mg/L (18 ºC)
Merck :14,7472
JECFA Number :1600
BRN :90741
Stability :Stable. Incompatible with strong oxidizing agents.
Cosmetics Ingredients Functions :SKIN CONDITIONING - MISCELLANEOUS
InChI :1S/C17H19NO3/c19-17(18-10-4-1-5-11-18)7-3-2-6-14-8-9-15-16(12-14)21-13-20-15/h2-3,6-9,12H,1,4-5,10-11,13H2/b6-2+,7-3+
InChIKey :MXXWOMGUGJBKIW-YPCIICBESA-N
SMILES :O=C(\C=C\C=C\c1ccc2OCOc2c1)N3CCCCC3
LogP :2.66
CAS DataBase Reference :94-62-2(CAS DataBase Reference)
NIST Chemistry Reference :Piperine(94-62-2)
EPA Substance Registry System :2,4-Pentadien-1-one, 5-(1,3-benzodioxol-5-yl)-1-(1-piperidinyl)-, (2E,4E)- (94-62-2)
Safety Information
| Symbol(GHS): |
 
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| Signal word: | Warning | |||||||||||||||||||||
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Description
Piperine is a natural alkaloid that can be isolated from black pepper. It activates transient receptor potential vanilloid type 1 receptor (TRPV1; EC50 = 38 μM) and modulates GABAA receptors (EC50s = 43-60 μM). At similar levels, piperine inhibits both monoamine oxidases (MAOs), with IC50 values of 21 and 7 μM for MAO-A and MAO-B, respectively. Like other natural compounds containing methylenedioxyphenyl substituents, piperine affects cytochrome P450 (CYP) isoforms, inhibiting CYP3A species (Ki ~ 5 μM) and increasing expression of CYP1A and CYP2B in liver. It also has a biphasic effect on P-glycoprotein activity.More related product prices
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