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ChemicalBook >> CAS DataBase List >> Pivaloyl chloride

Pivaloyl chloride

Pivaloyl chloride price.
  • $28.2 - $625
  • Product name: Pivaloyl chloride
  • CAS: 3282-30-2
  • MF: C5H9ClO
  • MW: 120.58
  • EINECS:221-921-6
  • MDL Number:MFCD00000709
  • Synonyms:2,2-dimethyl-propanoylchlorid ;Acetyl chloride, trimethyl-;Neopantanoyl chloride;PIVALOYL CHLORIDE(PVCL);Pivaloyl chloride(Trimethylacetyl chloride);Primethylacetyl chloride;Pivalpyl chloride;Pivaloyl chlorode
13 prices
Selected condition:
Brand
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Thermo Scientific Chemicals
  • TRC
Package
  • 5ml
  • 100mL
  • 250ML
  • 500ml
  • 2500ml
  • 1 kg
  • 5 g
  • 250 g
  • ManufacturerMedical Isotopes, Inc.
  • Product number69795
  • Product description2,2-DimethylpropanoylChloride
  • Packaging100mL
  • Price$625
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberT72605
  • Product descriptionTrimethylacetyl chloride 99%
  • Packaging5ml
  • Price$28.9
  • Updated2026-04-30
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberT72605
  • Product descriptionTrimethylacetyl chloride 99%
  • Packaging100ml
  • Price$35.6
  • Updated2026-04-30
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number8.01276
  • Product descriptionPivaloyl chloride for synthesis
  • Packaging250ML
  • Price$46.2
  • Updated2022-05-15
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberT72605
  • Product descriptionTrimethylacetyl chloride 99%
  • Packaging500ml
  • Price$90.1
  • Updated2026-04-30
  • Buy
  • ManufacturerThermo Scientific Chemicals
  • Product number14005
  • Product descriptionTrimethylacetyl chloride, 99% 99%
  • Packaging1 kg
  • Price$124
  • Updated2026-04-24
  • Buy
  • ManufacturerThermo Scientific Chemicals
  • Product numberA15051
  • Product descriptionTrimethylacetyl chloride, 98+%
  • Packaging2500ml
  • Price$230.65
  • Updated2026-04-24
  • Buy
  • ManufacturerThermo Scientific Chemicals
  • Product number14005
  • Product descriptionTrimethylacetyl chloride, 99% 99%
  • Packaging250 g
  • Price$48.2
  • Updated2026-04-24
  • Buy
  • ManufacturerThermo Scientific Chemicals
  • Product numberA15051
  • Product descriptionTrimethylacetyl chloride, 98+%
  • Packaging500ml
  • Price$71.65
  • Updated2026-04-24
  • Buy
  • ManufacturerThermo Scientific Chemicals
  • Product numberA15051
  • Product descriptionTrimethylacetyl chloride, 98+%
  • Packaging100ml
  • Price$30.6
  • Updated2026-04-24
  • Buy
  • ManufacturerThermo Scientific Chemicals
  • Product number14005
  • Product descriptionTrimethylacetyl chloride, 99% 99%
  • Packaging5 g
  • Price$28.2
  • Updated2026-04-24
  • Buy
  • ManufacturerTRC
  • Product numberD478010
  • Product description2,2-DimethylpropanoylChloride
  • Packaging100mL
  • Price$135
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberTRC-D478010-100ML
  • Product description2,2-Dimethylpropanoyl Chloride
  • Packaging100mL
  • Price$186
  • Updated2026-06-03
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Medical Isotopes, Inc. 69795 2,2-DimethylpropanoylChloride 100mL $625 2021-12-16 Buy
Sigma-Aldrich T72605 Trimethylacetyl chloride 99% 5ml $28.9 2026-04-30 Buy
Sigma-Aldrich T72605 Trimethylacetyl chloride 99% 100ml $35.6 2026-04-30 Buy
Sigma-Aldrich 8.01276 Pivaloyl chloride for synthesis 250ML $46.2 2022-05-15 Buy
Sigma-Aldrich T72605 Trimethylacetyl chloride 99% 500ml $90.1 2026-04-30 Buy
Thermo Scientific Chemicals 14005 Trimethylacetyl chloride, 99% 99% 1 kg $124 2026-04-24 Buy
Thermo Scientific Chemicals A15051 Trimethylacetyl chloride, 98+% 2500ml $230.65 2026-04-24 Buy
Thermo Scientific Chemicals 14005 Trimethylacetyl chloride, 99% 99% 250 g $48.2 2026-04-24 Buy
Thermo Scientific Chemicals A15051 Trimethylacetyl chloride, 98+% 500ml $71.65 2026-04-24 Buy
Thermo Scientific Chemicals A15051 Trimethylacetyl chloride, 98+% 100ml $30.6 2026-04-24 Buy
Thermo Scientific Chemicals 14005 Trimethylacetyl chloride, 99% 99% 5 g $28.2 2026-04-24 Buy
TRC D478010 2,2-DimethylpropanoylChloride 100mL $135 2021-12-16 Buy
TRC TRC-D478010-100ML 2,2-Dimethylpropanoyl Chloride 100mL $186 2026-06-03 Buy

Properties

Melting point :-56 °C
Boiling point :105-106 °C(lit.)
Density :0.980 g/mL at 20 °C
vapor density :>1 (vs air)
vapor pressure :36 mm Hg ( 20 °C)
refractive index :n20/D 1.412(lit.)
Flash point :48 °F
storage temp. :Store below +30°C.
solubility :Miscible with acetonitrile.
form :Liquid
color :Clear almost colorless to light pink
explosive limit :1.9-7.4%(V)
Water Solubility :Hydrolysis
Sensitive :Moisture Sensitive
BRN :385668
Stability :Hygroscopic, Moisture Sensitive, Volatile
InChI :1S/C5H9ClO/c1-5(2,3)4(6)7/h1-3H3
InChIKey :JVSFQJZRHXAUGT-UHFFFAOYSA-N
LogP :1.680 (est)
CAS DataBase Reference :3282-30-2(CAS DataBase Reference)
NIST Chemistry Reference :Propanoyl chloride, 2,2-dimethyl-(3282-30-2)
EPA Substance Registry System :Propanoyl chloride, 2,2-dimethyl- (3282-30-2)

Safety Information

Symbol(GHS): Flame (GHS02)Corrosion (GHS05)Skull and Crossbones (GHS06)Health Hazard (GHS08)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H290 May be corrosive to metals Corrosive to Metals Category 1 Warning P234, P390, P404
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H313 May be harmful in contact with skin Acute toxicity,dermal Category 5 P312
H314 Causes severe skin burns and eye damage Skin corrosion/irritation Category 1A, B, C Danger P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
H330 Fatal if inhaled Acute toxicity,inhalation Category 1, 2 Danger P260, P271, P284, P304+P340, P310,P320, P403+P233, P405, P501
H370 Causes damage to organs Specific target organ toxicity, single exposure Category 1 Danger P260, P264, P270, P307+P311, P321,P405, P501
H402 Harmful to aquatic life Hazardous to the aquatic environment, acute hazard Category 3
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233 Keep container tightly closed.
P234 Keep only in original container.
P240 Ground/bond container and receiving equipment.
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242 Use only non-sparking tools.
P243 Take precautionary measures against static discharge.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P284 Wear respiratory protection.
P301+P330+P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P363 Wash contaminated clothing before reuse.
P370+P378 In case of fire: Use … for extinction.
P390 Absorb spillage to prevent material damage.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P403+P235 Store in a well-ventilated place. Keep cool.
P405 Store locked up.
P406 Store in corrosive resistant/… container with a resistant inner liner.
P501 Dispose of contents/container to..…

Description

Trimethylacetyl chloride is used as a precursor in the preparation of tert-butyl peroxypivalate, guttiferon A derivatives, which is potential for the treatment of malaria. It is used as a raw material in the production of synthetic acidamide medicament and phenol ester medicament. In addition to this, it is used for the synthesis of active pharmaceutical ingredients such as aminobenzylpenicilin, cephalexin, cefazolin, dipivefrin and dipivalyl epinephrine. It is also used in heavy polymerization, N-acylating agent for amines, Schiff bases, pyrrolidinones as well as an O-acylating agent for alcohols, lactones and saccharides.

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