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ChemicalBook >> CAS DataBase List >> Rebamipide

Rebamipide

Rebamipide price.
  • $6 - $1593.9
  • Product name: Rebamipide
  • CAS: 90098-04-7
  • MF: C19H15ClN2O4
  • MW: 370.79
  • EINECS:1308068-626-2
  • MDL Number:MFCD00866895
  • Synonyms:(+-)-1,2-dihydro-alpha-((4-chlorobenzoyl)amino)-2-oxo-4-quinolinepropanoica ;(+-)-2-(4-chlorobenzoylamino)-3-(2(1h)-quinolinon-4-yl)propionicacid ;Mucosta;Proamipide;2-dihydro-alpha-((4-chlorobenzoyl)amino)-2-oxo- (+-)-4-quinolinepropanoic acid;2-(4-Chlorobenzoylamino)-3-(1,2-dihydro-2-oxo-4-quinolyl)propionic acid;2-(4-CHLOROBENZAMIDO)-3-(2-OXO-1,2-DIHYDROQUINOLIN-4-YL)PROPANOIC ACID;OPC-12759, Mucosta, α-[(4-Chlorobenzoyl)-amino]-1,2-dihydro-2-oxo-4-quinolinepropanoic Acid
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  • aablocks
  • Activate Scientific
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Package
  • 10mM(in1mLDMSO)
  • 5mg
  • EvaluationSample
  • 1mg
  • 10mM(1mLinDMSO)
  • 10MG
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  • 1g
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  • Manufactureraablocks
  • Product numberAA00IMHG
  • Product description2-(4-Chloro-benzoylamino)-3-(2-hydroxy-quinolin-4-yl)-propionic acid 98%
  • Packaging1mg
  • Price$8
  • Updated2026-05-29
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  • Manufactureraablocks
  • Product numberAA00IMHG
  • Product description2-(4-Chloro-benzoylamino)-3-(2-hydroxy-quinolin-4-yl)-propionic acid ≥98%
  • Packaging1g
  • Price$10
  • Updated2026-05-29
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  • Manufactureraablocks
  • Product numberAA00IMHG
  • Product description2-(4-Chloro-benzoylamino)-3-(2-hydroxy-quinolin-4-yl)-propionic acid ≥98%
  • Packaging5g
  • Price$13
  • Updated2026-05-29
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  • Manufactureraablocks
  • Product numberAA00IMHG
  • Product description2-(4-Chloro-benzoylamino)-3-(2-hydroxy-quinolin-4-yl)-propionic acid ≥98%
  • Packaging10g
  • Price$24
  • Updated2026-05-29
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  • Manufactureraablocks
  • Product numberAA00IMHG
  • Product description2-(4-Chloro-benzoylamino)-3-(2-hydroxy-quinolin-4-yl)-propionic acid 98%
  • Packaging25g
  • Price$40
  • Updated2026-05-29
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  • Manufactureraablocks
  • Product numberAA00IMHG
  • Product description2-(4-Chloro-benzoylamino)-3-(2-hydroxy-quinolin-4-yl)-propionic acid ≥98%
  • Packaging100g
  • Price$144
  • Updated2026-05-29
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  • ManufacturerActivate Scientific
  • Product numberAS112633
  • Product descriptionRebamipide 98%
  • Packaging1g
  • Price$89
  • Updated2021-12-16
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  • ManufacturerActivate Scientific
  • Product numberAS112633
  • Product descriptionRebamipide 98%
  • Packaging5G
  • Price$307
  • Updated2021-12-16
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  • ManufacturerAHH
  • Product numberAPI-1763
  • Product descriptionRebamipide 98%
  • Packaging100g
  • Price$850
  • Updated2021-12-16
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  • ManufacturerAHH
  • Product numberAPI-1763
  • Product descriptionRebamipide 97%
  • Packaging100g
  • Price$850
  • Updated2026-05-26
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  • ManufacturerAK Scientific
  • Product numberA636
  • Product descriptionRebamipide
  • Packaging25g
  • Price$703
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product numberJ11732
  • Product descriptionRebamipide >98%(HPLC),powder
  • Packaging100mg
  • Price$88
  • Updated2026-06-04
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  • ManufacturerAK Scientific
  • Product numberJ55007
  • Product descriptionRebamipide
  • Packaging5g
  • Price$176
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product numberJ55007
  • Product descriptionRebamipide 95%
  • Packaging25g
  • Price$46
  • Updated2026-06-04
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  • ManufacturerAK Scientific
  • Product numberA636
  • Product descriptionRebamipide 98%(HPLC)
  • Packaging25g
  • Price$62
  • Updated2026-06-04
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  • ManufacturerAK Scientific
  • Product numberJ11732
  • Product descriptionRebamipide >98%(HPLC),powder
  • Packaging25mg
  • Price$30
  • Updated2026-06-04
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Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00IMHG 2-(4-Chloro-benzoylamino)-3-(2-hydroxy-quinolin-4-yl)-propionic acid 98% 1mg $8 2026-05-29 Buy
aablocks AA00IMHG 2-(4-Chloro-benzoylamino)-3-(2-hydroxy-quinolin-4-yl)-propionic acid ≥98% 1g $10 2026-05-29 Buy
aablocks AA00IMHG 2-(4-Chloro-benzoylamino)-3-(2-hydroxy-quinolin-4-yl)-propionic acid ≥98% 5g $13 2026-05-29 Buy
aablocks AA00IMHG 2-(4-Chloro-benzoylamino)-3-(2-hydroxy-quinolin-4-yl)-propionic acid ≥98% 10g $24 2026-05-29 Buy
aablocks AA00IMHG 2-(4-Chloro-benzoylamino)-3-(2-hydroxy-quinolin-4-yl)-propionic acid 98% 25g $40 2026-05-29 Buy
aablocks AA00IMHG 2-(4-Chloro-benzoylamino)-3-(2-hydroxy-quinolin-4-yl)-propionic acid ≥98% 100g $144 2026-05-29 Buy
Activate Scientific AS112633 Rebamipide 98% 1g $89 2021-12-16 Buy
Activate Scientific AS112633 Rebamipide 98% 5G $307 2021-12-16 Buy
AHH API-1763 Rebamipide 98% 100g $850 2021-12-16 Buy
AHH API-1763 Rebamipide 97% 100g $850 2026-05-26 Buy
AK Scientific A636 Rebamipide 25g $703 2021-12-16 Buy
AK Scientific J11732 Rebamipide >98%(HPLC),powder 100mg $88 2026-06-04 Buy
AK Scientific J55007 Rebamipide 5g $176 2021-12-16 Buy
AK Scientific J55007 Rebamipide 95% 25g $46 2026-06-04 Buy
AK Scientific A636 Rebamipide 98%(HPLC) 25g $62 2026-06-04 Buy
AK Scientific J11732 Rebamipide >98%(HPLC),powder 25mg $30 2026-06-04 Buy

Properties

Melting point :288-290°C dec.
Boiling point :695.0±55.0 °C(Predicted)
Density :1.394±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :DMSO: >5mg/mL
pka :3.38±0.10(Predicted)
form :powder
color :white
Merck :14,8124
InChI :InChI=1S/C19H15ClN2O4/c20-13-7-5-11(6-8-13)18(24)22-16(19(25)26)9-12-10-17(23)21-15-4-2-1-3-14(12)15/h1-8,10,16H,9H2,(H,21,23)(H,22,24)(H,25,26)
InChIKey :ALLWOAVDORUJLA-UHFFFAOYSA-N
SMILES :C(C1=CC(=O)NC2=CC=CC=C12)C(C(=O)O)NC(C1C=CC(Cl)=CC=1)=O
CAS DataBase Reference :90098-04-7(CAS DataBase Reference)

Safety Information

Symbol(GHS): Skull and Crossbones (GHS06)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger P264, P270, P301+P310, P321, P330,P405, P501
Precautionary statements:
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

Description

Rebamipide is a quinolinone derivative that stimulates endogenous PGE2 generation in gastric mucosa, enhancing gastric mucosal defense in a COX-2-dependent manner.
Rebamipide has been shown to inhibit the production of reactive oxygen species and to decrease cytokine release induced by H. pylori infection.
A daily oral dose of 100 mg/kg was found to be protective against the development of pyloric channel ulcers in Mongolian gerbils infected with H. pylori.
In addition to the stomach, rebamipide can also enhance secretion of mucin covering the conjunctiva and cornea, which is important for tear film adhesion.
Rebamipide, a gastroprotective drug, was developed in Japan and was proven to be superior to cetraxate, the former most prescribed drug of the same category, in 1989 in the treatment for gastric ulcers. The initially discovered basic mechanisms of action of rebamipide included its action as a prostaglandin inducer and oxygen free-radical scavenger. In the last 5 years, several basic and clinical studies have been performed for functional dyspepsia, chronic gastritis, NSAID-induced gastrointestinal injuries, gastric ulcer following eradication therapy for Helicobacter pylori, gastric ulcer after endoscopic surgery and ulcerative colitis. In addition, several molecules have been identified as therapeutic targets of rebamipide to explain its pleiotropic pharmacological actions.

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