SWAINSONINE
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- $45 - $7868
- Product name: SWAINSONINE
- CAS: 72741-87-8
- MF: C8H15NO3
- MW: 173.21
- EINECS:
- MDL Number:MFCD00017554
- Synonyms:8-indolizinetriol,octahydro-,(1s,2r,8r,8ar)-2 ;(1S,2S,8R,8AR)-TRIHYDROXYINDOLIZIDINE;(1S,2R,8R,8AR)-1,2,8-OCTAHYDROINDOLIZIDINETRIOL;8ALPHA,BETA-INDOLIZIDINE-1,2ALPHA,8BETA-TRIOL;8ALPHA,BETA-INDOLIZIDINE-1ALPHA,2ALPHA,8BETA-TRIOL;8A-BETA-INDOLIZIDINE-1ALPHA,2ALPHA,8BETA-TRIOL;8A,B-INDOLIZIDINE-1,2A,8B-TRIOL;8A,B-OCTAHYDROINDOLIZIDINE-1A,2A,8B-TRIOL
73 prices
Selected condition：
Brand
- aablocks
- AHH
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Apolloscientific
- Arctom
- AvaChem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 0.1mg
- 10mM*1mLinWater(Solution)
- 0.5mg
- 1
- 500μg
- 2mg
- 2.5mg
- 1 unit
- 500 μg
- 500ug
- 0.005g
- 5mg
- 10mg
- 100mg
- 1mg
- 25mg
- 50mg
- 10mM*1mLinWater(Solid+Solvent)
- Manufactureraablocks
- Product numberAA0062AP
- Product descriptionSwainsonine ≥98%
- Packaging1mg
- Price$112
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0062AP
- Product descriptionSwainsonine ≥98%
- Packaging5mg
- Price$462
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0062AP
- Product descriptionSwainsonine ≥98%
- Packaging10mg
- Price$807
- Updated2026-05-28
- Buy
- ManufacturerAHH
- Product numberMT-58882
- Product descriptionSwainsonine 98%
- Packaging0.005g
- Price$370
- Updated2021-12-16
- Buy
- ManufacturerAHH
- Product numberMT-58882
- Product descriptionSwainsonine 97%
- Packaging0.005g
- Price$370
- Updated2026-05-25
- Buy
- ManufacturerAHH
- Product numberMT-58882
- Product descriptionSwainsonine 97%
- Packaging0.005g
- Price$370
- Updated2026-05-26
- Buy
- ManufacturerAK Scientific
- Product number2057AH
- Product descriptionSwainsonine
- Packaging1mg
- Price$210
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA581288
- Product descriptionSwainsonine 98%
- Packaging1mg
- Price$249
- Updated2026-06-05
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0004300
- Product descriptionSWAINSONINE 95.00%
- Packaging1MG
- Price$205.8
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0004300
- Product descriptionSWAINSONINE 95.00%
- Packaging10MG
- Price$1593.9
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7316
- Product descriptionSwainsonine
- Packaging10mg
- Price$1112
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB7316
- Product descriptionSwainsonine
- Packaging5mg
- Price$636
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB7316
- Product descriptionSwainsonine
- Packaging1mg
- Price$113
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7316
- Product descriptionSwainsonine
- Packaging1mg
- Price$151
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB7316
- Product descriptionSwainsonine
- Packaging500ug
- Price$80
- Updated2026-05-06
- Buy
- ManufacturerApolloscientific
- Product numberBICL4200
- Product descriptionSwainsonine >99%
- Packaging1mg
- Price$156
- Updated2026-06-04
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA0062AP | Swainsonine ≥98% | 1mg | $112 | 2026-05-28 | Buy |
| aablocks | AA0062AP | Swainsonine ≥98% | 5mg | $462 | 2026-05-28 | Buy |
| aablocks | AA0062AP | Swainsonine ≥98% | 10mg | $807 | 2026-05-28 | Buy |
| AHH | MT-58882 | Swainsonine 98% | 0.005g | $370 | 2021-12-16 | Buy |
| AHH | MT-58882 | Swainsonine 97% | 0.005g | $370 | 2026-05-25 | Buy |
| AHH | MT-58882 | Swainsonine 97% | 0.005g | $370 | 2026-05-26 | Buy |
| AK Scientific | 2057AH | Swainsonine | 1mg | $210 | 2021-12-16 | Buy |
| Ambeed | A581288 | Swainsonine 98% | 1mg | $249 | 2026-06-05 | Buy |
| American Custom Chemicals Corporation | API0004300 | SWAINSONINE 95.00% | 1MG | $205.8 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0004300 | SWAINSONINE 95.00% | 10MG | $1593.9 | 2021-12-16 | Buy |
| ApexBio Technology | B7316 | Swainsonine | 10mg | $1112 | 2026-05-06 | Buy |
| ApexBio Technology | B7316 | Swainsonine | 5mg | $636 | 2026-05-06 | Buy |
| ApexBio Technology | B7316 | Swainsonine | 1mg | $113 | 2021-12-16 | Buy |
| ApexBio Technology | B7316 | Swainsonine | 1mg | $151 | 2026-05-06 | Buy |
| ApexBio Technology | B7316 | Swainsonine | 500ug | $80 | 2026-05-06 | Buy |
| Apolloscientific | BICL4200 | Swainsonine >99% | 1mg | $156 | 2026-06-04 | Buy |
Properties
Melting point :148-149°C
Boiling point :353.3±21.0 °C(Predicted)
Density :1.38±0.1 g/cm3 (20 ºC 760 Torr)
storage temp. :-20°C
solubility :H2O: soluble1mg/mL
pka :14.01±0.60(Predicted)
form :lyophilized powder
color :white to faint yellow
biological source :synthetic
Water Solubility :Soluble to 50 mM in water
BRN :4175740
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO, ethanol or distilled water may be stored at -20°C for up to 3 months.
InChI :1S/C8H15NO3/c10-5-2-1-3-9-4-6(11)8(12)7(5)9/h5-8,10-12H,1-4H2/t5-,6-,7,8-/m1/s1
InChIKey :FXUAIOOAOAVCGD-DCDLSZRSSA-N
SMILES :O[C@@H]1CCCN2C[C@@H](O)[C@@H](O)C12
CAS DataBase Reference :72741-87-8
Boiling point :353.3±21.0 °C(Predicted)
Density :1.38±0.1 g/cm3 (20 ºC 760 Torr)
storage temp. :-20°C
solubility :H2O: soluble1mg/mL
pka :14.01±0.60(Predicted)
form :lyophilized powder
color :white to faint yellow
biological source :synthetic
Water Solubility :Soluble to 50 mM in water
BRN :4175740
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO, ethanol or distilled water may be stored at -20°C for up to 3 months.
InChI :1S/C8H15NO3/c10-5-2-1-3-9-4-6(11)8(12)7(5)9/h5-8,10-12H,1-4H2/t5-,6-,7,8-/m1/s1
InChIKey :FXUAIOOAOAVCGD-DCDLSZRSSA-N
SMILES :O[C@@H]1CCCN2C[C@@H](O)[C@@H](O)C12
CAS DataBase Reference :72741-87-8
Safety Information
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Description
Swainsonine is an indolizidine alkaloid naturally found in certain plants including locoweed that inhibits N-linked glycoside hydrolases, preventing the processing of asparagine-linked glycoproteins. It reversibly inhibits lysosomal α-mannosidase and Golgi α-mannosidase II (IC50 = 0.2 μM). Swainsonine is used to study the role of N-linked glycosylation in cellular processes and has been shown to have antiproliferative and antimetastatic effects of cancer cells in culture and in mice. The inhibition of α-mannosidase activity in lysosomes produces an accumulation of partially-processed oligosaccharides and glycoproteins, giving rise to lysosomal storage disease. Swainsonine toxicity in herbivores results in a condition known as locoism, characterized by hyperactivity, aggression, stiff and clumsy gait, low head carriage, salivation, seizures, and apparent blindness, culminating in increased miscoordination, weakness and death.More related product prices
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