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ChemicalBook >> CAS DataBase List >> Sitafloxacin

Sitafloxacin

Sitafloxacin price.
  • $48 - $11880
  • Product name: Sitafloxacin
  • CAS: 127254-12-0
  • MF: C19H18ClF2N3O3
  • MW: 409.81
  • EINECS:1308068-626-2
  • MDL Number:MFCD00903720
  • Synonyms:spifloxacin;7-[(4S)-4-Amino-6-azaspiro[2.4]heptan-6-yl]-8-chloro-6-fluoro-1-[(2S)-2-fluorocyclopropyl]-4-oxoquinoline-3-carboxylic acid;3-Quinolinecarboxylic acid, 7-[(7S)-7-aMino-5-azaspiro[2.4]hept-5-yl]-8-chloro-6-fluoro-1-[(1R,2S)-2-fluorocyclopropyl]-1,4-dihydro-4-oxo-;Sitafloxacin anhydrous;7-((S)-7-Amino-5-azaspiro[2.4]heptan-5-yl)-8-chloro-6-fluoro-1-((1R,2S)-2-fluorocyclopropyl)-4;Sitafloxacfn;Sitfloxacfn;Sitafloxacin-d4
35 prices
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Brand
  • aablocks
  • ACHEMBLOCK
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • Matrix Scientific
Package
  • 2mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100MG
  • 1.00g
  • 1G
  • 5g
  • 5.00g
  • Manufactureraablocks
  • Product numberAA000WR7
  • Product descriptionSitafloxacin
  • Packaging2mg
  • Price$48
  • Updated2026-05-25
  • Buy
  • Manufactureraablocks
  • Product numberAA000WR7
  • Product descriptionSitafloxacin
  • Packaging5mg
  • Price$65
  • Updated2026-05-25
  • Buy
  • Manufactureraablocks
  • Product numberAA000WR7
  • Product descriptionSitafloxacin
  • Packaging10mg
  • Price$93
  • Updated2026-05-25
  • Buy
  • Manufactureraablocks
  • Product numberAA000WR7
  • Product descriptionSitafloxacin
  • Packaging25mg
  • Price$139
  • Updated2026-05-25
  • Buy
  • Manufactureraablocks
  • Product numberAA000WR7
  • Product descriptionSitafloxacin
  • Packaging50mg
  • Price$199
  • Updated2026-05-25
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberR16059
  • Product descriptionSitafloxacin 99%
  • Packaging100MG
  • Price$395
  • Updated2026-05-25
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberR16059
  • Product descriptionSitafloxacin 99%
  • Packaging100MG
  • Price$395
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberR16059
  • Product descriptionSitafloxacin 99%
  • Packaging25MG
  • Price$175
  • Updated2026-05-25
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberR16059
  • Product descriptionSitafloxacin 99%
  • Packaging25MG
  • Price$175
  • Updated2026-05-27
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0006381
  • Product descriptionSITAFLOXACIN 95.00%
  • Packaging1G
  • Price$3405.15
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB3322
  • Product descriptionSitafloxacin
  • Packaging10mg
  • Price$224
  • Updated2026-05-06
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  • ManufacturerApexBio Technology
  • Product numberB3322
  • Product descriptionSitafloxacin
  • Packaging50mg
  • Price$679
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB3322
  • Product descriptionSitafloxacin
  • Packaging5mg
  • Price$119
  • Updated2026-05-06
  • Buy
  • ManufacturerBiosynth
  • Product numberFS103799
  • Product descriptionSitafloxacin
  • Packaging5mg
  • Price$250
  • Updated2026-06-04
  • Buy
  • ManufacturerBiosynth
  • Product numberFS103799
  • Product descriptionSitafloxacin
  • Packaging10mg
  • Price$305.9
  • Updated2026-06-04
  • Buy
  • ManufacturerBiosynth
  • Product numberFS103799
  • Product descriptionSitafloxacin
  • Packaging25mg
  • Price$611.75
  • Updated2026-06-04
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA000WR7 Sitafloxacin 2mg $48 2026-05-25 Buy
aablocks AA000WR7 Sitafloxacin 5mg $65 2026-05-25 Buy
aablocks AA000WR7 Sitafloxacin 10mg $93 2026-05-25 Buy
aablocks AA000WR7 Sitafloxacin 25mg $139 2026-05-25 Buy
aablocks AA000WR7 Sitafloxacin 50mg $199 2026-05-25 Buy
ACHEMBLOCK R16059 Sitafloxacin 99% 100MG $395 2026-05-25 Buy
ACHEMBLOCK R16059 Sitafloxacin 99% 100MG $395 2026-05-27 Buy
ACHEMBLOCK R16059 Sitafloxacin 99% 25MG $175 2026-05-25 Buy
ACHEMBLOCK R16059 Sitafloxacin 99% 25MG $175 2026-05-27 Buy
American Custom Chemicals Corporation API0006381 SITAFLOXACIN 95.00% 1G $3405.15 2021-12-16 Buy
ApexBio Technology B3322 Sitafloxacin 10mg $224 2026-05-06 Buy
ApexBio Technology B3322 Sitafloxacin 50mg $679 2026-05-06 Buy
ApexBio Technology B3322 Sitafloxacin 5mg $119 2026-05-06 Buy
Biosynth FS103799 Sitafloxacin 5mg $250 2026-06-04 Buy
Biosynth FS103799 Sitafloxacin 10mg $305.9 2026-06-04 Buy
Biosynth FS103799 Sitafloxacin 25mg $611.75 2026-06-04 Buy

Properties

Boiling point :629.2±55.0 °C(Predicted)
Density :1.63±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: slightly soluble; DMSO: slightly soluble; Methanol: slightly soluble
form :A crystalline solid
pka :6.39±0.50(Predicted)
Appearance :white solid
InChIKey :PNUZDKCDAWUEGK-CYZMBNFOSA-N
SMILES :N1([C@@H]2C[C@@H]2F)C2=C(C=C(F)C(N3C[C@@H](N)C4(CC4)C3)=C2Cl)C(=O)C(C(O)=O)=C1
CAS DataBase Reference :127254-12-0(CAS DataBase Reference)

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Sitafloxacin hydrate is the newest member (fourth generation) of the fluoroquinolone family of antibiotics that exhibits broad spectrum activity against many Gram-positive, Gramnegative, and anaerobic clinical isolates, including strains resistant to other fluoroquinolones. Since the launch of the first fluoroquinolone norfloxacin (patented in 1978), 20 other versions have made it to market with ciprofloxacin and levofloxacin experiencing the most prevalent usage. The mechanism of action involves inhibition of bacterial type II topoisomerases, both DNA gyrase and topoisomerase IV. By inhibiting these enzymes and preventing DNA supercoiling, cell division is disrupted leading to cell death. In Gram-negative bacteria, the primary target appears to be gyrase, whereas topoisomerase IV is involved in Gram-positive bacteria. Dual inhibition is attractive for widespread activity and avoidance of resistance as both encoding genes would have to acquire mutations.

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