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ChemicalBook >> CAS DataBase List >> TUG 891

TUG 891

TUG 891 price.
  • $12 - $1600
  • Product name: TUG 891
  • CAS: 1374516-07-0
  • MF: C23H21FO3
  • MW: 364.41
  • EINECS:
  • MDL Number:MFCD22421654
  • Synonyms:TUG 891;4-[(4-Fluoro-4'-methyl[1,1'-biphenyl]-2-yl)methoxy]-benzenepropanoic acid;CS-2448;TUG 891;TUG-891;Benzenepropanoic acid, 4-[(4-fluoro-4'-methyl[1,1'-biphenyl]-2-yl)methoxy]-;3-(4-{[5-fluoro-2-(4-methylphenyl)phenyl]methoxy}phenyl)propanoic acid;Inhibitor,inhibit,Free Fatty Acid Receptor,TUG-891,FFAR;3-{4-[(4-Fluoro-4'-methyl-2-biphenylyl)methoxy]phenyl}propanoic acid
59 prices
Selected condition:
Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • Ambeed
  • ApexBio Technology
  • Arctom
  • Axon Medchem
  • Biorbyt Ltd
  • Biosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Tocris
  • TRC
Package
  • 0.5mg
  • 2mg
  • 500mg
  • 10mM*1mLinDMSO(Solution)
  • 10
  • 50
  • 10mM*1mLinDMSO
  • 1g
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 10mM*1mLinDMSO(Solid+Solvent)
  • Manufactureraablocks
  • Product numberAA009FB7
  • Product description3-(4-((4-Fluoro-4'-methyl-[1,1'-biphenyl]-2-yl)methoxy)phenyl)propanoic acid 95%
  • Packaging1mg
  • Price$12
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA009FB7
  • Product description3-(4-((4-Fluoro-4'-methyl-[1,1'-biphenyl]-2-yl)methoxy)phenyl)propanoic acid 95%
  • Packaging5mg
  • Price$23
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA009FB7
  • Product description3-(4-((4-Fluoro-4'-methyl-[1,1'-biphenyl]-2-yl)methoxy)phenyl)propanoic acid 95%
  • Packaging10mg
  • Price$33
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA009FB7
  • Product description3-(4-((4-Fluoro-4'-methyl-[1,1'-biphenyl]-2-yl)methoxy)phenyl)propanoic acid 95%
  • Packaging25mg
  • Price$53
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA009FB7
  • Product description3-(4-((4-Fluoro-4'-methyl-[1,1'-biphenyl]-2-yl)methoxy)phenyl)propanoic acid 95%
  • Packaging50mg
  • Price$89
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA009FB7
  • Product description3-(4-((4-Fluoro-4'-methyl-[1,1'-biphenyl]-2-yl)methoxy)phenyl)propanoic acid 95%
  • Packaging100mg
  • Price$151
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA009FB7
  • Product description3-(4-((4-Fluoro-4'-methyl-[1,1'-biphenyl]-2-yl)methoxy)phenyl)propanoic acid 95%
  • Packaging250mg
  • Price$256
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberY230531
  • Product descriptionTUG-891 98%
  • Packaging100MG
  • Price$180
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberY230531
  • Product descriptionTUG-891 98%
  • Packaging250MG
  • Price$365
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product number6118DN
  • Product description3-(4-{[5-Fluoro-2-(4-methylphenyl)phenyl]methoxy}phenyl)propanoicacid
  • Packaging10mg
  • Price$282
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number6118DN
  • Product description3-(4-{[5-Fluoro-2-(4-methylphenyl)phenyl]methoxy}phenyl)propanoicacid
  • Packaging25mg
  • Price$500
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA844329
  • Product descriptionTUG-891 95+%
  • Packaging50mg
  • Price$228
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA844329
  • Product descriptionTUG-891 95+%
  • Packaging25mg
  • Price$175
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA844329
  • Product descriptionTUG-891 95+%
  • Packaging10mg
  • Price$134
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA844329
  • Product descriptionTUG-891 95+%
  • Packaging5mg
  • Price$73
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5651
  • Product descriptionTUG 891
  • Packaging10mg
  • Price$140
  • Updated2026-05-06
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA009FB7 3-(4-((4-Fluoro-4'-methyl-[1,1'-biphenyl]-2-yl)methoxy)phenyl)propanoic acid 95% 1mg $12 2026-05-28 Buy
aablocks AA009FB7 3-(4-((4-Fluoro-4'-methyl-[1,1'-biphenyl]-2-yl)methoxy)phenyl)propanoic acid 95% 5mg $23 2026-05-28 Buy
aablocks AA009FB7 3-(4-((4-Fluoro-4'-methyl-[1,1'-biphenyl]-2-yl)methoxy)phenyl)propanoic acid 95% 10mg $33 2026-05-28 Buy
aablocks AA009FB7 3-(4-((4-Fluoro-4'-methyl-[1,1'-biphenyl]-2-yl)methoxy)phenyl)propanoic acid 95% 25mg $53 2026-05-28 Buy
aablocks AA009FB7 3-(4-((4-Fluoro-4'-methyl-[1,1'-biphenyl]-2-yl)methoxy)phenyl)propanoic acid 95% 50mg $89 2026-05-28 Buy
aablocks AA009FB7 3-(4-((4-Fluoro-4'-methyl-[1,1'-biphenyl]-2-yl)methoxy)phenyl)propanoic acid 95% 100mg $151 2026-05-28 Buy
aablocks AA009FB7 3-(4-((4-Fluoro-4'-methyl-[1,1'-biphenyl]-2-yl)methoxy)phenyl)propanoic acid 95% 250mg $256 2026-05-28 Buy
ACHEMBLOCK Y230531 TUG-891 98% 100MG $180 2026-05-27 Buy
ACHEMBLOCK Y230531 TUG-891 98% 250MG $365 2026-05-27 Buy
AK Scientific 6118DN 3-(4-{[5-Fluoro-2-(4-methylphenyl)phenyl]methoxy}phenyl)propanoicacid 10mg $282 2021-12-16 Buy
AK Scientific 6118DN 3-(4-{[5-Fluoro-2-(4-methylphenyl)phenyl]methoxy}phenyl)propanoicacid 25mg $500 2021-12-16 Buy
Ambeed A844329 TUG-891 95+% 50mg $228 2021-12-16 Buy
Ambeed A844329 TUG-891 95+% 25mg $175 2021-12-16 Buy
Ambeed A844329 TUG-891 95+% 10mg $134 2021-12-16 Buy
Ambeed A844329 TUG-891 95+% 5mg $73 2021-12-16 Buy
ApexBio Technology B5651 TUG 891 10mg $140 2026-05-06 Buy

Properties

Boiling point :540.8±50.0 °C(Predicted)
Density :1.199±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :DMSO:30.0(Max Conc. mg/mL);82.32(Max Conc. mM)
DMF:5.0(Max Conc. mg/mL);13.72(Max Conc. mM)
Ethanol:1.0(Max Conc. mg/mL);2.74(Max Conc. mM) form :Powder
pka :4.70±0.10(Predicted)
color :White to off-white
InChI :1S/C23H21FO3/c1-16-2-7-18(8-3-16)22-12-9-20(24)14-19(22)15-27-21-10-4-17(5-11-21)6-13-23(25)26/h2-5,7-12,14H,6,13,15H2,1H3,(H,25,26)
InChIKey :LPGBXHWIQNZEJB-UHFFFAOYSA-N
SMILES :Fc1cc(c(cc1)c3ccc(cc3)C)COc2ccc(cc2)CCC(=O)O

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

GPR120 (free fatty acid receptor 4; FFAR4) is a G protein-coupled receptor (GPCR) expressed in intestine, adipocytes, and pro-inflammatory macrophages that is activated by long chain free fatty acids. ω-3 Fatty acids, such as docosahexaenoic acid and eicosapentaenoic acid , initiate GPR120 signaling resulting in inhibition of toll-like receptor and TNF-α inflammatory signaling pathways in a β-arrestin2/TAB1 dependent manner. TUG-891 is a potent and selective agonist of GPR120 with pEC50 values of 7.36 and 7.77 for human and mouse GPR120, respectively. It activates GPR40 (FFAR1) with a pEC50 value of 4.19 and shows no activity at GPR41 (FFAR3) or GPR43 (FFAR2).

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