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ChemicalBook >> CAS DataBase List >> Tacrolimus

Tacrolimus

$23 - $2409
Product name: Tacrolimus
CAS: 104987-11-3
MF: C44H69NO12
MW: 804.02
EINECS:1308068-626-2
MDL Number:MFCD00869853
Synonyms:(2-propenyl)-,(3s-(3r*(e(1s*,3s*,4s*)),4s*,5r*,8s*,9e,12r*,14r*,15s*,16r*,18s* ;,19s*,26ar*))- ;16-dimethoxy-4,10,12,18-tetramethyl-8-3-(2-(4-hydroxy-3-methoxycyclohexyl)-1 ;15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-, [3S-[3R*[E(1S*,3S*,4S*)],4S*,5R*,8S*,9E,12R*,14R*,15S*,16R*,18S*,19S*,26aR*]]-;L 679934;FK-506：FR-900506;Fujimycin Prozraf;Tacrolimus,micronisedandpharmagrade

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aablocks
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5MG
10mM(in 1mL DMSO)
25MG
0.025g
10mM(in1mLDMSO)
10mM*1mLinDMSO
10mg
20mg
50mg
100mg
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Manufactureraablocks
Product numberAA0039I8
Product description(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone 98%
Packaging100mg
Price$38
Updated2026-05-28
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Manufactureraablocks
Product numberAA0039I8
Product description(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone 98%
Packaging250mg
Price$76
Updated2026-05-28
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Manufactureraablocks
Product numberAA0039I8
Product description(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone 98%
Packaging1g
Price$186
Updated2026-05-28
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Manufactureraablocks
Product numberAA0039I8
Product description(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone 98%
Packaging50mg
Price$23
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA0039I8
Product description(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone 95%
Packaging5g
Price$802
Updated2026-05-28
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Manufactureraablocks
Product numberAA0039I8
Product description(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone 95%
Packaging10g
Price$1342
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA0039I8
Product description(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone 95%
Packaging25g
Price$2409
Updated2026-05-28
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ManufacturerACHEMBLOCK
Product numberT95026
Product descriptionTacrolimus 98%
Packaging5G
Price$520
Updated2026-05-25
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ManufacturerACHEMBLOCK
Product numberT95026
Product descriptionTacrolimus 98%
Packaging5G
Price$520
Updated2026-05-27
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ManufacturerACHEMBLOCK
Product numberT95026
Product descriptionTacrolimus 98%
Packaging1G
Price$160
Updated2026-05-25
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ManufacturerACHEMBLOCK
Product numberT95026
Product descriptionTacrolimus 98%
Packaging1G
Price$160
Updated2026-05-27
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ManufacturerAHH
Product numberAPI-1770
Product descriptionTacrolimus 97%
Packaging0.025g
Price$580
Updated2026-05-26
Buy

ManufacturerAK Scientific
Product numberJ40076
Product descriptionTacrolimus
Packaging10mg
Price$56
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA335856
Product description(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone 98+%
Packaging1g
Price$192
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA335856
Product description(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone 98+%
Packaging250mg
Price$75
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA335856
Product description(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone 98+%
Packaging50mg
Price$31
Updated2021-12-16
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
aablocks	AA0039I8	(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone 98%	100mg	$38	2026-05-28	Buy
aablocks	AA0039I8	(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone 98%	250mg	$76	2026-05-28	Buy
aablocks	AA0039I8	(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone 98%	1g	$186	2026-05-28	Buy
aablocks	AA0039I8	(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone 98%	50mg	$23	2026-05-28	Buy
aablocks	AA0039I8	(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone 95%	5g	$802	2026-05-28	Buy
aablocks	AA0039I8	(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone 95%	10g	$1342	2026-05-28	Buy
aablocks	AA0039I8	(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone 95%	25g	$2409	2026-05-28	Buy
ACHEMBLOCK	T95026	Tacrolimus 98%	5G	$520	2026-05-25	Buy
ACHEMBLOCK	T95026	Tacrolimus 98%	5G	$520	2026-05-27	Buy
ACHEMBLOCK	T95026	Tacrolimus 98%	1G	$160	2026-05-25	Buy
ACHEMBLOCK	T95026	Tacrolimus 98%	1G	$160	2026-05-27	Buy
AHH	API-1770	Tacrolimus 97%	0.025g	$580	2026-05-26	Buy
AK Scientific	J40076	Tacrolimus	10mg	$56	2021-12-16	Buy
Ambeed	A335856	(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone 98+%	1g	$192	2021-12-16	Buy
Ambeed	A335856	(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone 98+%	250mg	$75	2021-12-16	Buy
Ambeed	A335856	(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone 98+%	50mg	$31	2021-12-16	Buy

Next Last

Properties

Melting point :113-115°C
Boiling point :871.7±75.0 °C(Predicted)
Density :1.19±0.1 g/cm3(Predicted)
Flash point :2℃
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :DMSO: >3 mg/mL
form :solid
pka :9.97±0.70(Predicted)
color :white
optical activity :+62.223 (CHCl3)
Water Solubility :Freely soluble in DMSO or ethanol. Poorly soluble in water.Soluble in dimethyl sulfoxide, ethanol, water, acetone, chloroform, ethyl acetate, ether, methanol and dimethyl formamide.
BCS Class :2
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
InChIKey :QJJXYPPXXYFBGM-LFZNUXCKSA-N
CAS DataBase Reference :104987-11-3(CAS DataBase Reference)

Safety Information

Symbol(GHS):

Signal word:

Danger

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	Pictogram	P-Codes
H301	Toxic if swalloed	Acute toxicity,oral	Category 3	Danger		P264, P270, P301+P310, P321, P330,P405, P501
H373	May cause damage to organs through prolonged or repeated exposure	Specific target organ toxicity, repeated exposure	Category 2	Warning		P260, P314, P501

Precautionary statements:

P202	Do not handle until all safety precautions have been read and understood.
P260	Do not breathe dust/fume/gas/mist/vapours/spray.
P264	Wash hands thoroughly after handling.
P264	Wash skin thouroughly after handling.
P270	Do not eat, drink or smoke when using this product.
P280	Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310	IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

Description

Interacts with the immunophilins cyclophilin and FKBP-12.Tacrolimus is used as an immunosuppressive drug that blocks T cell proliferation in vitro. It is also used in the treatment of other T cell-mediated diseases such as eczema, Kimura's disease and Cushing's syndrome. Further, it is used as a research tool in chemically induced dimerization applications. In addition, it is used in liver transplantation and to suppress the inflammation in ulcerative cells. In dermatology, it is used as an ointment to treat eczema especially atopic dermatitis.

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Suppliers and manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd

$150.00
Tacrolimus Powder CAS:104987-11-3

Wuhan JiyunZen Tech Co., Ltd.

TACROLIMUS CAS:104987-11-3

Hebei Chuanghai Biotechnology Co., Ltd

$1.00
Tacrolimus CAS:104987-11-3

Shanghai Worldyang Chemical Co.,Ltd.

Tacrolimus CAS:104987-11-3

Hebei Yanxi Chemical Co., Ltd.

$50.00
Tacrolimus CAS:104987-11-3

Hebei Dangtong Import and export Co LTD

$40.00
Tacrolimus CAS:104987-11-3

Hubei Ipure Biology Co., Ltd

Shanghai Minbiotech Co., Ltd.

Jiangxi Huihe Chemical Co., Ltd.

Henan Tianfu Chemical Co.,Ltd.

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Tacrolimus

Properties

Safety Information

Description

Related product price

Suppliers and manufacturers