Tedizolid Phosphate
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- $5 - $4400
- Product name: Tedizolid Phosphate
- CAS: 856867-55-5
- MF: C17H16FN6O6P
- MW: 450.32
- EINECS:1592732-453-0
- MDL Number:MFCD28098176
- Synonyms:[(5R)-3-[3-fluoro-4-[6-(2-methyltetrazol-5-yl)pyridin-3-yl]phenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl dihydrogen phosphate;Tedizolid phosphate impurity A;(R) -3- (4- (2- (2- methyl-tetrazol-5-yl) pyridin-5-yl) -3-fluorophenyl) -5-hydroxymethyl-oxazolidin-2-one phosphate;(R) -3-(4-(2-(2-Methyltetrazol-5-yl)pyridine-5-yl)-3-fluorophenyl)-5-hydroxyMethyl oxazolidin-2-one phosphate;-3-(4-(2-(2-Methyltetrazol-5-yl)pyridine-5-yl)-3-fluorophenyl)-5-hydroxyMethyl oxazolidin-2-one phosphate;(5R)-3-[3-Fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)-3-pyridinyl]phenyl]-5-[(phosphonooxy)methyl]-2-oxazolidinone;Tedizolid Phosphate (TR-701);(R)-(3-(3-Fluoro-4-(6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl)phenyl)-2-oxooxazolidin-5-yl)met
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Brand
- A1 Biochem Labs
- aablocks
- ACHEMBLOCK
- AK Scientific
- Arctom
- Axon Medchem
- Biosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- J&W Pharmlab
- Matrix Scientific
- TRC
- Usbiological
Package
- 1mg
- 5mg
- 10mg
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- 100mg
- 250.00mg
- 250mg
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- 1.00g
- 1000mg
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- 2.5g
- 5.00g
- 5g
- 5000mg
- 10000mg
- ManufacturerA1 Biochem Labs
- Product numberA1-04308
- Product descriptionTedizolid Phosphate
- Packaging2.5g
- Price$1400
- Updated2021-12-16
- Buy
- Manufactureraablocks
- Product numberAA00G3OU
- Product descriptionTedizolid Phosphate 98%
- Packaging5mg
- Price$8
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00G3OU
- Product descriptionTedizolid Phosphate 98%
- Packaging10mg
- Price$10
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00G3OU
- Product descriptionTedizolid Phosphate ≥98%
- Packaging25mg
- Price$14
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00G3OU
- Product descriptionTedizolid Phosphate 98%
- Packaging100mg
- Price$15
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00G3OU
- Product descriptionTedizolid Phosphate 98%
- Packaging250mg
- Price$22
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00G3OU
- Product descriptionTedizolid Phosphate ≥98%
- Packaging1g
- Price$61
- Updated2026-05-28
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- Manufactureraablocks
- Product numberAA00G3OU
- Product descriptionTedizolid Phosphate ≥98%
- Packaging5g
- Price$209
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberO32465
- Product description(R)-(3-(3-Fluoro-4-(6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl)phenyl)-2-oxooxazolidin-5-yl)methyldihydrogenphosphate 98%
- Packaging100MG
- Price$165
- Updated2021-12-16
- Buy
- ManufacturerACHEMBLOCK
- Product numberO32465
- Product description(R)-(3-(3-Fluoro-4-(6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl)phenyl)-2-oxooxazolidin-5-yl)methyldihydrogenphosphate 98%
- Packaging1G
- Price$595
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ98599
- Product descriptionTedizolidPhosphate
- Packaging5mg
- Price$84
- Updated2021-12-16
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- ManufacturerAK Scientific
- Product numberJ98599
- Product descriptionTedizolidPhosphate
- Packaging1mg
- Price$25
- Updated2021-12-16
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- ManufacturerArctom
- Product numberAS039803
- Product descriptionTedizolidPhosphate ≥98%
- Packaging250mg
- Price$33
- Updated2021-12-16
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- ManufacturerArctom
- Product numberAS039803
- Product descriptionTedizolidPhosphate ≥98%
- Packaging50mg
- Price$16
- Updated2021-12-16
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- ManufacturerArctom
- Product numberAS039803
- Product descriptionTedizolidPhosphate ≥98%
- Packaging1g
- Price$71
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS039803
- Product descriptionTedizolidPhosphate ≥98%
- Packaging10mg
- Price$9
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| A1 Biochem Labs | A1-04308 | Tedizolid Phosphate | 2.5g | $1400 | 2021-12-16 | Buy |
| aablocks | AA00G3OU | Tedizolid Phosphate 98% | 5mg | $8 | 2026-05-28 | Buy |
| aablocks | AA00G3OU | Tedizolid Phosphate 98% | 10mg | $10 | 2026-05-28 | Buy |
| aablocks | AA00G3OU | Tedizolid Phosphate ≥98% | 25mg | $14 | 2026-05-28 | Buy |
| aablocks | AA00G3OU | Tedizolid Phosphate 98% | 100mg | $15 | 2026-05-28 | Buy |
| aablocks | AA00G3OU | Tedizolid Phosphate 98% | 250mg | $22 | 2026-05-28 | Buy |
| aablocks | AA00G3OU | Tedizolid Phosphate ≥98% | 1g | $61 | 2026-05-28 | Buy |
| aablocks | AA00G3OU | Tedizolid Phosphate ≥98% | 5g | $209 | 2026-05-28 | Buy |
| ACHEMBLOCK | O32465 | (R)-(3-(3-Fluoro-4-(6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl)phenyl)-2-oxooxazolidin-5-yl)methyldihydrogenphosphate 98% | 100MG | $165 | 2021-12-16 | Buy |
| ACHEMBLOCK | O32465 | (R)-(3-(3-Fluoro-4-(6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl)phenyl)-2-oxooxazolidin-5-yl)methyldihydrogenphosphate 98% | 1G | $595 | 2021-12-16 | Buy |
| AK Scientific | J98599 | TedizolidPhosphate | 5mg | $84 | 2021-12-16 | Buy |
| AK Scientific | J98599 | TedizolidPhosphate | 1mg | $25 | 2021-12-16 | Buy |
| Arctom | AS039803 | TedizolidPhosphate ≥98% | 250mg | $33 | 2021-12-16 | Buy |
| Arctom | AS039803 | TedizolidPhosphate ≥98% | 50mg | $16 | 2021-12-16 | Buy |
| Arctom | AS039803 | TedizolidPhosphate ≥98% | 1g | $71 | 2021-12-16 | Buy |
| Arctom | AS039803 | TedizolidPhosphate ≥98% | 10mg | $9 | 2021-12-16 | Buy |
Properties
Melting point :>235°C (dec.)
Boiling point :725.6±70.0 °C(Predicted)
Density :1.75±0.1 g/cm3(Predicted)
storage temp. :under inert gas (nitrogen or Argon) at 2-8°C
solubility :DMSO (Slightly, Sonicated)
form :Solid
pka :1.81±0.10(Predicted)
color :White to Off-White
Stability :Hygroscopic
InChIKey :QCGUSIANLFXSGE-GFCCVEGCSA-N
SMILES :O1[C@@H](COP(O)(O)=O)CN(C2=CC=C(C3=CC=C(C4=NN(C)N=N4)N=C3)C(F)=C2)C1=O
Boiling point :725.6±70.0 °C(Predicted)
Density :1.75±0.1 g/cm3(Predicted)
storage temp. :under inert gas (nitrogen or Argon) at 2-8°C
solubility :DMSO (Slightly, Sonicated)
form :Solid
pka :1.81±0.10(Predicted)
color :White to Off-White
Stability :Hygroscopic
InChIKey :QCGUSIANLFXSGE-GFCCVEGCSA-N
SMILES :O1[C@@H](COP(O)(O)=O)CN(C2=CC=C(C3=CC=C(C4=NN(C)N=N4)N=C3)C(F)=C2)C1=O
Safety Information
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Description
Tedizolid phosphate was approved by the US FDA in June 2014 for treatment of acute bacterial skin and skin structure infections caused by susceptible gram-positive pathogens, including MRSA. Tedizolid phosphate was discovered by Dong-A Pharmaceuticals in South Korea and developed in the USA by Cubist Pharmaceuticals (acquired from Trius Therapeutics in 2013, became a wholly owned subsidiary of Merck in 2015). The worldwide commercialization rights for tedizolid phosphate are divided between Cubist in the USA, Canada, and EU, and Bayer in Asia–Pacific, Latin America, and Africa. This second-generation oxazolidinone prodrug is rapidly converted to the active form tedizolid in the presence of endogenous phosphatases. It inhibits bacterial protein synthesis by binding to the 23S ribosomal RNA of the 50S subunit of the ribosome, preventing formation of the 70S ribosomal initiation complex, and is 4-fold to 16-fold more potent against staphylococci and enterococci compared to linezolid. 251 With high oral bioavailability (approximately 90%) and long half-life (approximately 12 hours), tedizolid phosphate is the first oxazolidinone antibiotic which can be dosed once daily either orally or intravenously.More related product prices
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