Temsirolimus
|
- $18 - $3239
- Product name: Temsirolimus
- CAS: 162635-04-3
- MF: C56H87NO16
- MW: 1030.29
- EINECS:686-177-0
- MDL Number:MFCD00934421
- Synonyms:42-[3-hydroxy-2-(hydroxymethyl)-2-methylpropa;Temsirolimus(CCI-779);TEMSIROLIMUS;CCL-779;Rapamycin 42-[3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoate;TeMsiroliMus (CCI-779, Torisel);rapaMycin 42-ester with 3-hydroxy-2-(hydroxyMethyl)-2-Methylpropionic acid;42-[3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoate]rapamycin
128 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Ambeed
- ApexBio Technology
- Arctom
- AvaChem
- Axon Medchem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- Chem-Impex
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TCI Chemical
- Thermo Scientific Chemicals
- Tocris
- TRC
- Usbiological
Package
- 20mg
- 500mg
- 10mM*1mLinDMSO(Solution)
- 10mM(in1mLDMSO)
- 10mM*1mLinDMSO(Solid+Solvent)
- 10.00g
- 10
- 25.00g
- 10mM*1mLinDMSO
- 100.00g
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 200mg
- 250mg
- 1G
- EvaluationSample
- Manufactureraablocks
- Product numberAA00IMI9
- Product description40-[3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoate]-rapamycin 95%
- Packaging1mg
- Price$18
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA00IMI9
- Product description40-[3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoate]-rapamycin 95%
- Packaging5mg
- Price$37
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA00IMI9
- Product description40-[3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoate]-rapamycin 95%
- Packaging10mg
- Price$55
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA00IMI9
- Product description40-[3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoate]-rapamycin 95%
- Packaging25mg
- Price$107
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA00IMI9
- Product description40-[3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoate]-rapamycin ≥98%
- Packaging100mg
- Price$406
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA00IMI9
- Product description40-[3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoate]-rapamycin ≥98%(HPLC)
- Packaging250mg
- Price$705
- Updated2026-05-29
- Buy
- ManufacturerACHEMBLOCK
- Product number10394
- Product descriptionTemsirolimus 98%
- Packaging100MG
- Price$356
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product number10394
- Product descriptionTemsirolimus 98%
- Packaging1G
- Price$1215
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product number10394
- Product descriptionTemsirolimus 98%
- Packaging25MG
- Price$135
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product number10394
- Product descriptionTemsirolimus 98%
- Packaging5MG
- Price$50
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product numberB622
- Product descriptionTemsirolimus
- Packaging25mg
- Price$257
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberB622
- Product descriptionTemsirolimus
- Packaging1mg
- Price$49
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA642622
- Product descriptionTemsirolimus 99%
- Packaging10mg
- Price$69
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA642622
- Product descriptionTemsirolimus 99%
- Packaging25mg
- Price$146
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA642622
- Product descriptionTemsirolimus 99%
- Packaging5mg
- Price$46
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA642622
- Product descriptionTemsirolimus 99%
- Packaging1g
- Price$1444
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00IMI9 | 40-[3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoate]-rapamycin 95% | 1mg | $18 | 2026-05-29 | Buy |
| aablocks | AA00IMI9 | 40-[3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoate]-rapamycin 95% | 5mg | $37 | 2026-05-29 | Buy |
| aablocks | AA00IMI9 | 40-[3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoate]-rapamycin 95% | 10mg | $55 | 2026-05-29 | Buy |
| aablocks | AA00IMI9 | 40-[3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoate]-rapamycin 95% | 25mg | $107 | 2026-05-29 | Buy |
| aablocks | AA00IMI9 | 40-[3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoate]-rapamycin ≥98% | 100mg | $406 | 2026-05-29 | Buy |
| aablocks | AA00IMI9 | 40-[3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoate]-rapamycin ≥98%(HPLC) | 250mg | $705 | 2026-05-29 | Buy |
| ACHEMBLOCK | 10394 | Temsirolimus 98% | 100MG | $356 | 2026-05-27 | Buy |
| ACHEMBLOCK | 10394 | Temsirolimus 98% | 1G | $1215 | 2026-05-27 | Buy |
| ACHEMBLOCK | 10394 | Temsirolimus 98% | 25MG | $135 | 2026-05-27 | Buy |
| ACHEMBLOCK | 10394 | Temsirolimus 98% | 5MG | $50 | 2026-05-27 | Buy |
| AK Scientific | B622 | Temsirolimus | 25mg | $257 | 2021-12-16 | Buy |
| AK Scientific | B622 | Temsirolimus | 1mg | $49 | 2021-12-16 | Buy |
| Ambeed | A642622 | Temsirolimus 99% | 10mg | $69 | 2021-12-16 | Buy |
| Ambeed | A642622 | Temsirolimus 99% | 25mg | $146 | 2021-12-16 | Buy |
| Ambeed | A642622 | Temsirolimus 99% | 5mg | $46 | 2021-12-16 | Buy |
| Ambeed | A642622 | Temsirolimus 99% | 1g | $1444 | 2021-12-16 | Buy |
Properties
Melting point :99-101°C
Boiling point :1048.4±75.0 °C(Predicted)
Density :1.21
Flash point :587.8℃
storage temp. :room temp
solubility :Soluble in chloroform, methanol.
pka :10.40±0.70(Predicted)
form :powder
color :white to off-white
Merck :14,9142
InChIKey :CBPNZQVSJQDFBE-FUXHJELOSA-N
Boiling point :1048.4±75.0 °C(Predicted)
Density :1.21
Flash point :587.8℃
storage temp. :room temp
solubility :Soluble in chloroform, methanol.
pka :10.40±0.70(Predicted)
form :powder
color :white to off-white
Merck :14,9142
InChIKey :CBPNZQVSJQDFBE-FUXHJELOSA-N
Safety Information
| Symbol(GHS): |
|
|||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Danger | |||||||||||||||||||||
| Hazard statements: |
|
|||||||||||||||||||||
| Precautionary statements: |
|
Description
Rapamycin is an immunosuppressant that specifically interacts with the cytosolic FK-binding protein 12 to form a complex which inhibits the mammalian target of rapamycin (mTOR) pathway by directly binding to mTOR Complex 1. Temsirolimus is a dihydroxymethyl propionic acid ester of rapamycin with improved solubility that specifically inhibits mTOR signaling with a potency similar to that of rapamycin. Treatment with temsirolimus leads to cell cycle arrest in the G1 phase and also inhibition of tumor angiogenesis by reducing synthesis of VEGF. Temsirolimus demonstrates cytostatic activity in several xenograft models of human tumors in nude mice, including glioblastomas, prostate carcinoma, pancreatic, liver, and breast cancers, and medulloblastoma.Related product price
-
3-(4-Hydroxyphenyl)propionic acid
$5-2100 -
Rapamycin
$9-6160 -
CHLOROPHOSPHONAZO III
$55-987
Suppliers and manufacturers
Henan Tianfu Chemical Co.,Ltd.
Shanghai Yingrui Biopharma Co., Ltd.
ATK CHEMICAL COMPANY LIMITED
Biochempartner
Xiamen AmoyChem Co., Ltd
BOC Sciences
