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ChemicalBook >> CAS DataBase List >> Trifluoroacetamide

Trifluoroacetamide

Trifluoroacetamide price.
  • $6 - $4124
  • Product name: Trifluoroacetamide
  • CAS: 354-38-1
  • MF: C2H2F3NO
  • MW: 113.04
  • EINECS:206-559-9
  • MDL Number:MFCD00008008
  • Synonyms:Three fluoroacetaMide;TRIFLUOROACETAMIDE;TRIFLUOROACETIC ACID AMIDE;2,2,2-trifluoro-acetamid ;TRIFLUOROACETAMIDE 98%;2,2,2-TRIFLOUROACETAMIDE;2,2,2-TRIFLOUROACET-AMIDE (TFAA);Trifluoroacetamide98%
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  • ManufacturerAK Scientific
  • Product numberJ99253
  • Product description2,2,2-Trifluoroacetamide 97%
  • Packaging5g
  • Price$13
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberI135
  • Product description2,2,2-Trifluoroacetamide
  • Packaging25g
  • Price$14
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberI135
  • Product description2,2,2-Trifluoroacetamide >99%(GC)
  • Packaging5g
  • Price$18
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ99253
  • Product description2,2,2-Trifluoroacetamide 97%
  • Packaging25g
  • Price$20
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberI135
  • Product description2,2,2-Trifluoroacetamide >99%(GC)
  • Packaging25g
  • Price$27
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ99253
  • Product description2,2,2-Trifluoroacetamide 97%
  • Packaging100g
  • Price$40
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberI135
  • Product description2,2,2-Trifluoroacetamide >99%(GC)
  • Packaging100g
  • Price$55
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ99253
  • Product description2,2,2-Trifluoroacetamide
  • Packaging500g
  • Price$73
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ99253
  • Product description2,2,2-Trifluoroacetamide 97%
  • Packaging500g
  • Price$90
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberI135
  • Product description2,2,2-Trifluoroacetamide >99%(GC)
  • Packaging500g
  • Price$126
  • Updated2026-06-04
  • Buy
  • ManufacturerAmbeed
  • Product numberA305077
  • Product description2,2,2-Trifluoroacetamide 97%
  • Packaging1kg
  • Price$116
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA305077
  • Product description2,2,2-Trifluoroacetamide 97%
  • Packaging500g
  • Price$65
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA305077
  • Product description2,2,2-Trifluoroacetamide 97%
  • Packaging100g
  • Price$18
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA305077
  • Product description2,2,2-Trifluoroacetamide 97%
  • Packaging10g
  • Price$6
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA305077
  • Product description2,2,2-Trifluoroacetamide 97%
  • Packaging25g
  • Price$10
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHCH0017082
  • Product description2,2,2-TRIFLUOROACETAMIDE 95.00%
  • Packaging100G
  • Price$2333.29
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific J99253 2,2,2-Trifluoroacetamide 97% 5g $13 2026-06-04 Buy
AK Scientific I135 2,2,2-Trifluoroacetamide 25g $14 2021-12-16 Buy
AK Scientific I135 2,2,2-Trifluoroacetamide >99%(GC) 5g $18 2026-06-04 Buy
AK Scientific J99253 2,2,2-Trifluoroacetamide 97% 25g $20 2026-06-04 Buy
AK Scientific I135 2,2,2-Trifluoroacetamide >99%(GC) 25g $27 2026-06-04 Buy
AK Scientific J99253 2,2,2-Trifluoroacetamide 97% 100g $40 2026-06-04 Buy
AK Scientific I135 2,2,2-Trifluoroacetamide >99%(GC) 100g $55 2026-06-04 Buy
AK Scientific J99253 2,2,2-Trifluoroacetamide 500g $73 2021-12-16 Buy
AK Scientific J99253 2,2,2-Trifluoroacetamide 97% 500g $90 2026-06-04 Buy
AK Scientific I135 2,2,2-Trifluoroacetamide >99%(GC) 500g $126 2026-06-04 Buy
Ambeed A305077 2,2,2-Trifluoroacetamide 97% 1kg $116 2021-12-16 Buy
Ambeed A305077 2,2,2-Trifluoroacetamide 97% 500g $65 2021-12-16 Buy
Ambeed A305077 2,2,2-Trifluoroacetamide 97% 100g $18 2021-12-16 Buy
Ambeed A305077 2,2,2-Trifluoroacetamide 97% 10g $6 2021-12-16 Buy
Ambeed A305077 2,2,2-Trifluoroacetamide 97% 25g $10 2021-12-16 Buy
American Custom Chemicals Corporation HCH0017082 2,2,2-TRIFLUOROACETAMIDE 95.00% 100G $2333.29 2021-12-16 Buy

Properties

Melting point :65-70 °C (lit.)
Boiling point :162.5 °C (lit.)
Density :1.4176 (estimate)
bulk density :960kg/m3
Flash point :162-164°C
storage temp. :Store below +30°C.
solubility :460 g/L (20°C)
form :Crystalline Powder or Crystals
pka :12.33±0.50(Predicted)
color :White to pale yellow or beige
PH :3.6 (460g/l, H2O, 23℃)
Water Solubility :460 g/L (20 ºC)
BRN :1753625
InChI :1S/C2H2F3NO/c3-2(4,5)1(6)7/h(H2,6,7)
InChIKey :NRKYWOKHZRQRJR-UHFFFAOYSA-N
SMILES :NC(=O)C(F)(F)F
LogP :0.725 at 23℃ and pH4.83
Dissociation constant :0 at 23℃
CAS DataBase Reference :354-38-1(CAS DataBase Reference)
NIST Chemistry Reference :Acetamide, 2,2,2-trifluoro-(354-38-1)
EPA Substance Registry System :Acetamide, 2,2,2-trifluoro- (354-38-1)

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

2,2,2-Trifluoroacetamide used in a convenient alternative to the Gabriel synthesis of primary amines from halides by N-alkylation followed by cleavage of the readily-hydrolyzed trifluoroacetyl group and for improved N-alkylation under phase-transfer conditions allowing successive alkylation with different alkyl groups.

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