VR23
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- $15 - $2419
- Product name: VR23
- CAS: 1624602-30-7
- MF: C19H16ClN5O6S
- MW: 477.88
- EINECS:
- MDL Number:MFCD28502093
- Synonyms:VR23;7-Chloro-4-[4-[(2,4-dinitrophenyl)sulfonyl]-1-piperazinyl]quinoline;VR23(VR-23);7-chloro-4-(4-((2,4-dinitrophenyl)sulfonyl)piperazin-1-yl)quinoline;CS-1579;Quinoline, 7-chloro-4-[4-[(2,4-dinitrophenyl)sulfonyl]-1-piperazinyl]-;VR23 >=98% (HPLC);VR23, 10 mM in DMSO
78 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- Adipogen Life Sciences
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Ark Pharm
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Sigma-Aldrich
- TRC
Package
- 5mg
- 10mg
- 10mM*1mLinDMSO
- 1mg
- 10mM*1mLinDMSO(Solid+Solvent)
- 25mg
- 50mg
- 100mg
- 200mg
- 250mg
- 0.5g
- 1g
- 5 mg
- 25 mg
- 10mM*1mLinDMSO(Solution)
- Manufactureraablocks
- Product numberAA001T2Z
- Product descriptionVR23 99
- Packaging25mg
- Price$69
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001T2Z
- Product descriptionVR23 99
- Packaging50mg
- Price$109
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001T2Z
- Product descriptionVR23 99
- Packaging100mg
- Price$171
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001T2Z
- Product descriptionVR23 99%
- Packaging10mg
- Price$37
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001T2Z
- Product descriptionVR23 99%
- Packaging5mg
- Price$27
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberP50924
- Product descriptionVR23 98%
- Packaging100MG
- Price$225
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberP50924
- Product descriptionVR23 98%
- Packaging25MG
- Price$95
- Updated2026-05-27
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3676-M025
- Product descriptionVR23 [Proteasome Inhibitor] ≥98%(HPLC)
- Packaging25mg
- Price$360
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3676-M005
- Product descriptionVR23 [Proteasome Inhibitor] ≥98%(HPLC)
- Packaging5mg
- Price$120
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3676-M005
- Product descriptionVR23[ProteasomeInhibitor] ≥98%(HPLC)
- Packaging5mg
- Price$85
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3676-M001
- Product descriptionVR23 [Proteasome Inhibitor] ≥98%(HPLC)
- Packaging1mg
- Price$30
- Updated2026-05-06
- Buy
- ManufacturerAK Scientific
- Product number6718DW
- Product descriptionCID73442847
- Packaging10mg
- Price$402
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number6718DW
- Product descriptionCID73442847
- Packaging25mg
- Price$714
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA142790
- Product description7-Chloro-4-(4-((2,4-dinitrophenyl)sulfonyl)piperazin-1-yl)quinoline 98+%
- Packaging1g
- Price$455
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA142790
- Product description7-Chloro-4-(4-((2,4-dinitrophenyl)sulfonyl)piperazin-1-yl)quinoline 98+%
- Packaging5mg
- Price$32
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA142790
- Product description7-Chloro-4-(4-((2,4-dinitrophenyl)sulfonyl)piperazin-1-yl)quinoline 98+%
- Packaging50mg
- Price$95
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA001T2Z | VR23 99 | 25mg | $69 | 2026-05-28 | Buy |
| aablocks | AA001T2Z | VR23 99 | 50mg | $109 | 2026-05-28 | Buy |
| aablocks | AA001T2Z | VR23 99 | 100mg | $171 | 2026-05-28 | Buy |
| aablocks | AA001T2Z | VR23 99% | 10mg | $37 | 2026-05-28 | Buy |
| aablocks | AA001T2Z | VR23 99% | 5mg | $27 | 2026-05-28 | Buy |
| ACHEMBLOCK | P50924 | VR23 98% | 100MG | $225 | 2026-05-27 | Buy |
| ACHEMBLOCK | P50924 | VR23 98% | 25MG | $95 | 2026-05-27 | Buy |
| Adipogen Life Sciences | AG-CR1-3676-M025 | VR23 [Proteasome Inhibitor] ≥98%(HPLC) | 25mg | $360 | 2026-05-06 | Buy |
| Adipogen Life Sciences | AG-CR1-3676-M005 | VR23 [Proteasome Inhibitor] ≥98%(HPLC) | 5mg | $120 | 2026-05-06 | Buy |
| Adipogen Life Sciences | AG-CR1-3676-M005 | VR23[ProteasomeInhibitor] ≥98%(HPLC) | 5mg | $85 | 2021-12-16 | Buy |
| Adipogen Life Sciences | AG-CR1-3676-M001 | VR23 [Proteasome Inhibitor] ≥98%(HPLC) | 1mg | $30 | 2026-05-06 | Buy |
| AK Scientific | 6718DW | CID73442847 | 10mg | $402 | 2021-12-16 | Buy |
| AK Scientific | 6718DW | CID73442847 | 25mg | $714 | 2021-12-16 | Buy |
| Ambeed | A142790 | 7-Chloro-4-(4-((2,4-dinitrophenyl)sulfonyl)piperazin-1-yl)quinoline 98+% | 1g | $455 | 2021-12-16 | Buy |
| Ambeed | A142790 | 7-Chloro-4-(4-((2,4-dinitrophenyl)sulfonyl)piperazin-1-yl)quinoline 98+% | 5mg | $32 | 2021-12-16 | Buy |
| Ambeed | A142790 | 7-Chloro-4-(4-((2,4-dinitrophenyl)sulfonyl)piperazin-1-yl)quinoline 98+% | 50mg | $95 | 2021-12-16 | Buy |
Properties
storage temp. :Store at -20°C
solubility :insoluble in EtOH; insoluble in H2O; ≥45.55 mg/mL in DMSO
form :Powder
color :Light yellow to yellow
InChI :1S/C19H16ClN5O6S/c20-13-1-3-15-16(11-13)21-6-5-17(15)22-7-9-23(10-8-22)32(30,31)19-4-2-14(24(26)27)12-18(19)25(28)29/h1-6,11-12H,7-10H2
InChIKey :PDQVZPPIHADUOO-UHFFFAOYSA-N
SMILES :[S](=O)(=O)(N2CCN(CC2)c3c4c(ncc3)cc(cc4)Cl)c1c(cc(cc1)[N+](=O)[O-])[N+](=O)[O-]
solubility :insoluble in EtOH; insoluble in H2O; ≥45.55 mg/mL in DMSO
form :Powder
color :Light yellow to yellow
InChI :1S/C19H16ClN5O6S/c20-13-1-3-15-16(11-13)21-6-5-17(15)22-7-9-23(10-8-22)32(30,31)19-4-2-14(24(26)27)12-18(19)25(28)29/h1-6,11-12H,7-10H2
InChIKey :PDQVZPPIHADUOO-UHFFFAOYSA-N
SMILES :[S](=O)(=O)(N2CCN(CC2)c3c4c(ncc3)cc(cc4)Cl)c1c(cc(cc1)[N+](=O)[O-])[N+](=O)[O-]
Safety Information
| Symbol(GHS): |
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| Signal word: | Warning | ||||||||||||||
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Description
VR23 is a chloroquine derivative that functions as a proteasome inhibitor (IC50s = 1 nM, 50-100 nM, and 3 μM for trypsin-like, chymotrypsin-like, and caspase-like proteasomes, respectively). It also deregulates the activity of cyclin E and other centrosomal proteins, resulting in the induction of multiple centrosome amplification, abnormal spindle formation, uneven cytokinesis, irreversible mitotic arrest, and eventually apoptosis that is specific to cancer cells. In combination with the chymotrypsin-like proteasome inhibitor bortezomib , VR23 can produce a synergistic effect in killing multiple myeloma cells, including those that are resistant to bortezomib.More related product prices
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