Vadimezan
|
- $9 - $20100
- Product name: Vadimezan
- CAS: 117570-53-3
- MF: C17H14O4
- MW: 282.29
- EINECS:700-141-4
- MDL Number:MFCD00870555
- Synonyms:5,6-dimethylxanthenoneacetic acid;vadimezan;(5,6-DIMETHYL-9-OXO-XANTHEN)-4-ACETIC ACID;5,6-Dimethyl-9-oxo-9H-xanthene-4-acetic acid;5,6-Dimethylxanthenone-4-acetic acid;NSC-640488;NSC-649488;ASA-404
121 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- AstaTech
- AvaChem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- Chem-Impex
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Matrix Scientific
- Oakwood
- Sigma-Aldrich
- TCI Chemical
- Tocris
- TRC
Package
- 2mg
- 10mM*1mLinDMSO(Solution)
- 0.1G
- 200mg
- 0.25G
- 250.00mg
- 1.00g
- 5.00g
- 10mM*1mLinDMSO(Solid+Solvent)
- 10
- 50
- 10mM*1mLinDMSO
- 1mlx10mM(inDMSO)
- 10g
- 10mM(in 1mL DMSO)
- 10mM(in1mLDMSO)
- 1mg
- 1unit
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- EvaluationSample
- 5G
- 10mM(1mLinDMSO)
- 250mg
- 1g
- Manufactureraablocks
- Product numberAA0035TX
- Product description9H-Xanthene-4-aceticacid, 5,6-dimethyl-9-oxo- 98%
- Packaging1mg
- Price$9
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0035TX
- Product description9H-Xanthene-4-aceticacid, 5,6-dimethyl-9-oxo- ≥98%
- Packaging5mg
- Price$10
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0035TX
- Product description9H-Xanthene-4-aceticacid, 5,6-dimethyl-9-oxo- 98%
- Packaging10mg
- Price$15
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0035TX
- Product description9H-Xanthene-4-aceticacid, 5,6-dimethyl-9-oxo- ≥98%
- Packaging25mg
- Price$16
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0035TX
- Product description9H-Xanthene-4-aceticacid, 5,6-dimethyl-9-oxo- 98%
- Packaging100mg
- Price$32
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0035TX
- Product description9H-Xanthene-4-aceticacid, 5,6-dimethyl-9-oxo- 98%
- Packaging250mg
- Price$64
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0035TX
- Product description9H-Xanthene-4-aceticacid, 5,6-dimethyl-9-oxo- 98%
- Packaging1g
- Price$194
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product number10336
- Product descriptionDMXAA 98%
- Packaging1G
- Price$215
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product number10336
- Product descriptionDMXAA 98%
- Packaging1G
- Price$215
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product number10336
- Product descriptionDMXAA 98%
- Packaging5G
- Price$970
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product number10336
- Product descriptionDMXAA 98%
- Packaging5G
- Price$970
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product numberSYN5518
- Product descriptionVadimezan
- Packaging100mg
- Price$1296
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA140665
- Product description2-(5,6-Dimethyl-9-oxo-9H-xanthen-4-yl)aceticacid 98+%
- Packaging5g
- Price$1101
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA140665
- Product description2-(5,6-Dimethyl-9-oxo-9H-xanthen-4-yl)aceticacid 98+%
- Packaging1g
- Price$299
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA140665
- Product description2-(5,6-Dimethyl-9-oxo-9H-xanthen-4-yl)aceticacid 98+%
- Packaging250mg
- Price$116
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA140665
- Product description2-(5,6-Dimethyl-9-oxo-9H-xanthen-4-yl)aceticacid 98+%
- Packaging10mg
- Price$32
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA0035TX | 9H-Xanthene-4-aceticacid, 5,6-dimethyl-9-oxo- 98% | 1mg | $9 | 2026-05-28 | Buy |
| aablocks | AA0035TX | 9H-Xanthene-4-aceticacid, 5,6-dimethyl-9-oxo- ≥98% | 5mg | $10 | 2026-05-28 | Buy |
| aablocks | AA0035TX | 9H-Xanthene-4-aceticacid, 5,6-dimethyl-9-oxo- 98% | 10mg | $15 | 2026-05-28 | Buy |
| aablocks | AA0035TX | 9H-Xanthene-4-aceticacid, 5,6-dimethyl-9-oxo- ≥98% | 25mg | $16 | 2026-05-28 | Buy |
| aablocks | AA0035TX | 9H-Xanthene-4-aceticacid, 5,6-dimethyl-9-oxo- 98% | 100mg | $32 | 2026-05-28 | Buy |
| aablocks | AA0035TX | 9H-Xanthene-4-aceticacid, 5,6-dimethyl-9-oxo- 98% | 250mg | $64 | 2026-05-28 | Buy |
| aablocks | AA0035TX | 9H-Xanthene-4-aceticacid, 5,6-dimethyl-9-oxo- 98% | 1g | $194 | 2026-05-28 | Buy |
| ACHEMBLOCK | 10336 | DMXAA 98% | 1G | $215 | 2026-05-25 | Buy |
| ACHEMBLOCK | 10336 | DMXAA 98% | 1G | $215 | 2026-05-27 | Buy |
| ACHEMBLOCK | 10336 | DMXAA 98% | 5G | $970 | 2026-05-25 | Buy |
| ACHEMBLOCK | 10336 | DMXAA 98% | 5G | $970 | 2026-05-27 | Buy |
| AK Scientific | SYN5518 | Vadimezan | 100mg | $1296 | 2021-12-16 | Buy |
| Ambeed | A140665 | 2-(5,6-Dimethyl-9-oxo-9H-xanthen-4-yl)aceticacid 98+% | 5g | $1101 | 2021-12-16 | Buy |
| Ambeed | A140665 | 2-(5,6-Dimethyl-9-oxo-9H-xanthen-4-yl)aceticacid 98+% | 1g | $299 | 2021-12-16 | Buy |
| Ambeed | A140665 | 2-(5,6-Dimethyl-9-oxo-9H-xanthen-4-yl)aceticacid 98+% | 250mg | $116 | 2021-12-16 | Buy |
| Ambeed | A140665 | 2-(5,6-Dimethyl-9-oxo-9H-xanthen-4-yl)aceticacid 98+% | 10mg | $32 | 2021-12-16 | Buy |
Properties
Melting point :259-261 °C
Boiling point :520.9±50.0 °C(Predicted)
Density :1.321±0.06 g/cm3(Predicted)
vapor pressure :0Pa at 20℃
storage temp. :2-8°C
solubility :DMSO: 17 mg/mL, soluble
form :solid
pka :4.21±0.10(Predicted)
color :light brown
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20°C for up to 3 months.
InChI :InChI=1S/C17H14O4/c1-9-6-7-13-15(20)12-5-3-4-11(8-14(18)19)17(12)21-16(13)10(9)2/h3-7H,8H2,1-2H3,(H,18,19)
InChIKey :XGOYIMQSIKSOBS-UHFFFAOYSA-N
SMILES :C1(=O)C2=C(C(C)=C(C)C=C2)OC2=C1C=CC=C2CC(O)=O
Boiling point :520.9±50.0 °C(Predicted)
Density :1.321±0.06 g/cm3(Predicted)
vapor pressure :0Pa at 20℃
storage temp. :2-8°C
solubility :DMSO: 17 mg/mL, soluble
form :solid
pka :4.21±0.10(Predicted)
color :light brown
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20°C for up to 3 months.
InChI :InChI=1S/C17H14O4/c1-9-6-7-13-15(20)12-5-3-4-11(8-14(18)19)17(12)21-16(13)10(9)2/h3-7H,8H2,1-2H3,(H,18,19)
InChIKey :XGOYIMQSIKSOBS-UHFFFAOYSA-N
SMILES :C1(=O)C2=C(C(C)=C(C)C=C2)OC2=C1C=CC=C2CC(O)=O
Safety Information
| Symbol(GHS): |
 
|
|||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Warning | |||||||||||||||||||||
| Hazard statements: |
|
|||||||||||||||||||||
| Precautionary statements: |
|
Description
DMXAA is a xanthene which acts as a tumor vascular disrupting agent, inducing apoptosis in tumor vascular endothelium resulting in necrosis at the tumor core. It potently activates the TANK-binding kinase 1-interferon regulatory factor 3 (TBK1/IRF3) signaling pathway in leukocytes, inducing type-I-interferon (IFN) production. Specifically, DMXAA activates the mitochondria- and endoplasmic reticulum-associated protein known as stimulator of interferon genes (STING), leading to TBK1/IRF3 signaling. DMXAA signals through mouse STING but not human STING. In addition, DMXAA significantly inhibits several kinases in endothelial cells, including the vascular endothelial growth factor (VEGF) receptors VEGFR1 and VEGFR2 (IC50 = 119 and 11 μM, respectively).Related product price
-
Poly(dimethylsiloxane)
$20-2858.63 -
ACETIC ACID
$7-3630.17 -
Methyl 2,2-dimethylphenylacetate
$5-1904
