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ChemicalBook >> CAS DataBase List >> Wnt Agonist

Wnt Agonist

Wnt Agonist price.
  • $16 - $6980
  • Product name: Wnt Agonist
  • CAS: 853220-52-7
  • MF: C19H18N4O3
  • MW: 350.37
  • EINECS:
  • MDL Number:MFCD09908087
  • Synonyms:AMBMP;CID 11210285 hydrochloride;N4-(1,3-benzodioxol-5-ylmethyl)-6-(3-methoxyphenyl)-2,4-pyrimidinediamine hydrochloride;Wnt agonist 1;2-Amino-4-(3,4-(methylenedioxy)benzylamino)-6-(3-methoxyphenyl)pyrimidine hydrochloride;Wnt agonist 1 (BML-284);N4-(1,3-Benzodioxol-5-ylmethyl)-6-(3-methoxyphenyl)-2,4-pyrimidinediamine;Wnt Agonist
95 prices
Selected condition:
Brand
  • aablocks
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Axon Medchem
  • Biorbyt Ltd
  • Biosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • JR MediChem
  • Matrix Scientific
  • Sigma-Aldrich
Package
  • 2mg
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 10mM*1mLinDMSO(Solution)
  • 1mg
  • 10mM*1mLinDMSO
  • 1mlx10mM(inDMSO)
  • 10mM(in1mLDMSO)
  • 5mg
  • 10mg
  • 25.00mg
  • 25mg
  • 50.00mg
  • 50mg
  • 100.00mg
  • 100mg
  • 200mg
  • 250mg
  • 500mg
  • 1g
  • 5g
  • Manufactureraablocks
  • Product numberAA00G3PE
  • Product descriptionBML-284 99%
  • Packaging1mg
  • Price$16
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00G3PE
  • Product descriptionBML-284 99%
  • Packaging5mg
  • Price$31
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00G3PE
  • Product descriptionBML-284 99%
  • Packaging10mg
  • Price$38
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00G3PE
  • Product descriptionBML-284 99%
  • Packaging25mg
  • Price$59
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00G3PE
  • Product descriptionBML-284 99%
  • Packaging50mg
  • Price$87
  • Updated2026-05-28
  • Buy
  • ManufacturerAK Scientific
  • Product number5764CS
  • Product descriptionWntAgonist
  • Packaging5mg
  • Price$201
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number5764CS
  • Product descriptionWntAgonist
  • Packaging50mg
  • Price$606
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0004755
  • Product descriptionN4-(1,3-BENZODIOXOL-5-YLMETHYL)-6-(3-METHOXYPHENYL)-2,4-PYRIMIDINEDIAMINE HYDROCHLORIDE 95.00%
  • Packaging5MG
  • Price$501.51
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6059
  • Product descriptionWnt agonist 1
  • Packaging200mg
  • Price$485
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6059
  • Product descriptionWnt agonist 1
  • Packaging50mg
  • Price$264
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6059
  • Product descriptionWnt agonist 1
  • Packaging10mM(in1mLDMSO)
  • Price$72
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6059
  • Product descriptionWnt agonist 1
  • Packaging10mg
  • Price$64
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6059
  • Product descriptionWntagonist1
  • Packaging200mg
  • Price$554
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberHY-19987
  • Product descriptionBML-284 99.99%
  • Packaging200mg
  • Price$770
  • Updated2026-05-25
  • Buy
  • ManufacturerArctom
  • Product numberHY-19987
  • Product descriptionBML-284 99.99%
  • Packaging200mg
  • Price$770
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-19987
  • Product descriptionBML-284 99.99%
  • Packaging5mg
  • Price$67
  • Updated2026-05-25
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00G3PE BML-284 99% 1mg $16 2026-05-28 Buy
aablocks AA00G3PE BML-284 99% 5mg $31 2026-05-28 Buy
aablocks AA00G3PE BML-284 99% 10mg $38 2026-05-28 Buy
aablocks AA00G3PE BML-284 99% 25mg $59 2026-05-28 Buy
aablocks AA00G3PE BML-284 99% 50mg $87 2026-05-28 Buy
AK Scientific 5764CS WntAgonist 5mg $201 2021-12-16 Buy
AK Scientific 5764CS WntAgonist 50mg $606 2021-12-16 Buy
American Custom Chemicals Corporation INB0004755 N4-(1,3-BENZODIOXOL-5-YLMETHYL)-6-(3-METHOXYPHENYL)-2,4-PYRIMIDINEDIAMINE HYDROCHLORIDE 95.00% 5MG $501.51 2021-12-16 Buy
ApexBio Technology B6059 Wnt agonist 1 200mg $485 2026-05-06 Buy
ApexBio Technology B6059 Wnt agonist 1 50mg $264 2026-05-06 Buy
ApexBio Technology B6059 Wnt agonist 1 10mM(in1mLDMSO) $72 2026-05-06 Buy
ApexBio Technology B6059 Wnt agonist 1 10mg $64 2026-05-06 Buy
ApexBio Technology B6059 Wntagonist1 200mg $554 2021-12-16 Buy
Arctom HY-19987 BML-284 99.99% 200mg $770 2026-05-25 Buy
Arctom HY-19987 BML-284 99.99% 200mg $770 2026-05-26 Buy
Arctom HY-19987 BML-284 99.99% 5mg $67 2026-05-25 Buy

Properties

Boiling point :623.4±65.0 °C(Predicted)
Density :1.353±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble20mg/mL, clear
form :Yellowish sticky solid
pka :6.62±0.10(Predicted)
color :white to beige
InChI :1S/C19H18N4O3/c1-24-14-4-2-3-13(8-14)15-9-18(23-19(20)22-15)21-10-12-5-6-16-17(7-12)26-11-25-16/h2-9H,10-11H2,1H3,(H3,20,21,22,23)
InChIKey :FABQUVYDAXWUQP-UHFFFAOYSA-N
SMILES :N(Cc3cc4c(cc3)OCO4)c1nc(nc(c1)c2cc(ccc2)OC)N

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Wnt Agonist is a cell-permeable pyrimidine compound that acts as, at an IC50 > 60 μM, a potent and selective activator of Wnt signaling. In addition to mimicking the effect of Wnt, Wnt Agonist has also induced β-catenin and T-cell fate-dependent transcriptional activity in HEK-293T cells at an EC50 = 700 nM. When applied to Xenopous embryos Wnt Agonist caused substantial head defects development. Wnt Agonist has also been observed to enhance beta cell expansion in vitro. The compound is beneficial for studying the effects of Wnt pathway due to the activation of Wnt without inhibiting the activity of GSK-3β.

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