XL413 (hydrochloride)
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- $30 - $1790
- Product name: XL413 (hydrochloride)
- CAS: 2062200-97-7
- MF: C14H13Cl2N3O2
- MW: 326.18
- EINECS:
- MDL Number:
- Synonyms:XL-413 hydrochloride,XL413 hydrochloride;XL413 xhydrochloride;XL413 hydrochloride, 10 mM in DMSO
35 prices
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Brand
- aablocks
- ACHEMBLOCK
- Arctom
- Axon Medchem
- Biosynth
- Cayman Chemical
- ChemScene
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 200mg
- 250MG
- 1 mg
- Manufactureraablocks
- Product numberAA01EQ45
- Product description(S)-8-Chloro-2-(pyrrolidin-2-yl)benzofuro[3,2-d]pyrimidin-4(3H)-one hydrochloride
- Packaging200mg
- Price$810
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01EQ45
- Product description(S)-8-Chloro-2-(pyrrolidin-2-yl)benzofuro[3,2-d]pyrimidin-4(3H)-one hydrochloride
- Packaging100mg
- Price$618
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01EQ45
- Product description(S)-8-Chloro-2-(pyrrolidin-2-yl)benzofuro[3,2-d]pyrimidin-4(3H)-one hydrochloride
- Packaging50mg
- Price$418
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01EQ45
- Product description(S)-8-Chloro-2-(pyrrolidin-2-yl)benzofuro[3,2-d]pyrimidin-4(3H)-one hydrochloride
- Packaging25mg
- Price$258
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01EQ45
- Product description(S)-8-Chloro-2-(pyrrolidin-2-yl)benzofuro[3,2-d]pyrimidin-4(3H)-one hydrochloride
- Packaging10mg
- Price$151
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01EQ45
- Product description(S)-8-Chloro-2-(pyrrolidin-2-yl)benzofuro[3,2-d]pyrimidin-4(3H)-one hydrochloride
- Packaging5mg
- Price$114
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01EQ45
- Product description(S)-8-Chloro-2-(pyrrolidin-2-yl)benzofuro[3,2-d]pyrimidin-4(3H)-one hydrochloride ≥98%
- Packaging1mg
- Price$33
- Updated2026-05-30
- Buy
- ManufacturerACHEMBLOCK
- Product numberY228870
- Product descriptionXL413 hydrochloride 97.00%
- Packaging250MG
- Price$1790
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY228870
- Product descriptionXL413 hydrochloride 97.00%
- Packaging25MG
- Price$355
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY228870
- Product descriptionXL413 hydrochloride 97.00%
- Packaging100MG
- Price$895
- Updated2026-05-27
- Buy
- ManufacturerArctom
- Product numberHY-15260A
- Product descriptionXL413monohydrochloride 99.65%
- Packaging100mg
- Price$855
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-15260A
- Product descriptionXL413monohydrochloride 99.65%
- Packaging50mg
- Price$570
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-15260A
- Product descriptionXL413monohydrochloride 99.65%
- Packaging10mg
- Price$190
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-15260A
- Product descriptionXL413monohydrochloride 99.65%
- Packaging5mg
- Price$137
- Updated2026-05-26
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2268
- Product descriptionXL 413 hydrochloride
- Packaging5mg
- Price$132
- Updated2026-05-19
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2268
- Product descriptionXL 413 hydrochloride
- Packaging25mg
- Price$396
- Updated2026-05-19
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA01EQ45 | (S)-8-Chloro-2-(pyrrolidin-2-yl)benzofuro[3,2-d]pyrimidin-4(3H)-one hydrochloride | 200mg | $810 | 2026-05-30 | Buy |
| aablocks | AA01EQ45 | (S)-8-Chloro-2-(pyrrolidin-2-yl)benzofuro[3,2-d]pyrimidin-4(3H)-one hydrochloride | 100mg | $618 | 2026-05-30 | Buy |
| aablocks | AA01EQ45 | (S)-8-Chloro-2-(pyrrolidin-2-yl)benzofuro[3,2-d]pyrimidin-4(3H)-one hydrochloride | 50mg | $418 | 2026-05-30 | Buy |
| aablocks | AA01EQ45 | (S)-8-Chloro-2-(pyrrolidin-2-yl)benzofuro[3,2-d]pyrimidin-4(3H)-one hydrochloride | 25mg | $258 | 2026-05-30 | Buy |
| aablocks | AA01EQ45 | (S)-8-Chloro-2-(pyrrolidin-2-yl)benzofuro[3,2-d]pyrimidin-4(3H)-one hydrochloride | 10mg | $151 | 2026-05-30 | Buy |
| aablocks | AA01EQ45 | (S)-8-Chloro-2-(pyrrolidin-2-yl)benzofuro[3,2-d]pyrimidin-4(3H)-one hydrochloride | 5mg | $114 | 2026-05-30 | Buy |
| aablocks | AA01EQ45 | (S)-8-Chloro-2-(pyrrolidin-2-yl)benzofuro[3,2-d]pyrimidin-4(3H)-one hydrochloride ≥98% | 1mg | $33 | 2026-05-30 | Buy |
| ACHEMBLOCK | Y228870 | XL413 hydrochloride 97.00% | 250MG | $1790 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y228870 | XL413 hydrochloride 97.00% | 25MG | $355 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y228870 | XL413 hydrochloride 97.00% | 100MG | $895 | 2026-05-27 | Buy |
| Arctom | HY-15260A | XL413monohydrochloride 99.65% | 100mg | $855 | 2026-05-26 | Buy |
| Arctom | HY-15260A | XL413monohydrochloride 99.65% | 50mg | $570 | 2026-05-26 | Buy |
| Arctom | HY-15260A | XL413monohydrochloride 99.65% | 10mg | $190 | 2026-05-26 | Buy |
| Arctom | HY-15260A | XL413monohydrochloride 99.65% | 5mg | $137 | 2026-05-26 | Buy |
| Axon Medchem | Axon2268 | XL 413 hydrochloride | 5mg | $132 | 2026-05-19 | Buy |
| Axon Medchem | Axon2268 | XL 413 hydrochloride | 25mg | $396 | 2026-05-19 | Buy |
Properties
storage temp. :Store at -20°C
solubility :DMSO:0.2(Max Conc. mg/mL);0.613(Max Conc. mM)
PBS (pH:7.2):10.0(Max Conc. mg/mL);30.66(Max Conc. mM) form :A crystalline solid
color :White to off-white
solubility :DMSO:0.2(Max Conc. mg/mL);0.613(Max Conc. mM)
PBS (pH:7.2):10.0(Max Conc. mg/mL);30.66(Max Conc. mM) form :A crystalline solid
color :White to off-white
Safety Information
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Description
XL413 is a potent inhibitor of Cdc7 (IC50 = 3.4 nM). It is >60, >10, and >300-fold selective for Cdc7 over CK2, PIM1, and a panel of over 100 protein kinases, respectively. XL413 inhibits the growth of MDA-MB-231T and COLO 205 cells (IC50s = 118 and 140 nM, respectively). It inhibits Cdc7-specific phosphorylation of mini-chromosome maintenance protein (MCM2) and induces cell cycle accumulation in the S and G2 phases in MDA-MB-231T and COLO 205 cells that overexpress Cdc7. In vivo, XL413 inhibits MCM2 phosphorylation (ED50 = <3 mg/kg) and reduces tumor growth in a COLO 205 mouse xenograft model when administered orally at doses of 10, 30, and 100 mg/kg.Suppliers and manufacturers
BOC Sciences
Shanghai EFE Biological Technology Co., Ltd.
Shanghai YuanYe Biotechnology Co., Ltd.
Shanghai Rechem science Co., Ltd.
Beijing Jin Ming Biotechnology Co., Ltd.
Chengdu Saint - Kay Biotechnology Co., Ltd.
Fan De(Beijing) Biotechnology Co., Ltd.
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Shanghai hongqu biomedical technology co. LTD
