YK-4-279
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- $35 - $1853.5
- Product name: YK-4-279
- CAS: 1037184-44-3
- MF: C17H13Cl2NO4
- MW: 366.2
- EINECS:
- MDL Number:MFCD18382120
- Synonyms:YK-4-279;4,7-Dichloro-1,3-dihydro-3-hydroxy-3-[2-(4-methoxyphenyl)-2-oxoethyl]-2H-indol-2-one;4,7-Dichloro-1,3-dihydro-3-hydroxy-3-[2-(4-methoxyphenyl)-2-oxoethyl]-2H-indol-2-one YK-4-279;YK-4-279;YK 4-279;4,7-dichloro-3-hydroxy-3-[2-(4-methoxyphenyl)-2-oxoethyl]-1H-indol-2-one;CS-1785;2H-Indol-2-one, 4,7-dichloro-1,3-dihydro-3-hydroxy-3-[2-(4-methoxyphenyl)-2-oxoethyl]-;YK-4-279 USP/EP/BP
67 prices
Selected condition：
Brand
- aablocks
- Absolute Chiral
- ACHEMBLOCK
- AK Scientific
- Alichem
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Axon Medchem
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Tocris
- TRC
Package
- 10mM*1mLinDMSO(Solid+Solvent)
- 25mg
- 10mM(in1mLDMSO)
- 10mM*1mLinDMSO(Solution)
- 50mg
- 50
- 1.00g
- 10
- 100.00mg
- 250.00mg
- 1MG
- 2mg
- 5mg
- 100mg
- 10mM(in 1mL DMSO)
- 10MG
- 250mg
- 500mg
- 1g
- 5g
- Manufactureraablocks
- Product numberAA008SO1
- Product description4,7-Dichloro-1,3-dihydro-3-hydroxy-3-[2-(4-methoxyphenyl)-2-oxoethyl]-2H-indol-2-one 98
- Packaging5mg
- Price$64
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008SO1
- Product description4,7-Dichloro-1,3-dihydro-3-hydroxy-3-[2-(4-methoxyphenyl)-2-oxoethyl]-2H-indol-2-one 99%
- Packaging100mg
- Price$83
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008SO1
- Product description4,7-Dichloro-1,3-dihydro-3-hydroxy-3-[2-(4-methoxyphenyl)-2-oxoethyl]-2H-indol-2-one 98
- Packaging2mg
- Price$48
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008SO1
- Product description4,7-Dichloro-1,3-dihydro-3-hydroxy-3-[2-(4-methoxyphenyl)-2-oxoethyl]-2H-indol-2-one 98%
- Packaging250mg
- Price$176
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008SO1
- Product description4,7-Dichloro-1,3-dihydro-3-hydroxy-3-[2-(4-methoxyphenyl)-2-oxoethyl]-2H-indol-2-one 98%
- Packaging1g
- Price$463
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008SO1
- Product description4,7-Dichloro-1,3-dihydro-3-hydroxy-3-[2-(4-methoxyphenyl)-2-oxoethyl]-2H-indol-2-one 98%
- Packaging5g
- Price$1653
- Updated2026-05-28
- Buy
- ManufacturerAbsolute Chiral
- Product numberO3572-00-N
- Product description4,7-dichloro-3-hydroxy-3-(2-(4-methoxyphenyl)-2-oxoethyl)indolin-2-one 95%
- Packaging250mg
- Price$198
- Updated2026-05-23
- Buy
- ManufacturerAbsolute Chiral
- Product numberO3572-00-N
- Product description4,7-dichloro-3-hydroxy-3-(2-(4-methoxyphenyl)-2-oxoethyl)indolin-2-one 95%
- Packaging100mg
- Price$98
- Updated2026-05-23
- Buy
- ManufacturerACHEMBLOCK
- Product numberQ65696
- Product description4,7-dichloro-3-hydroxy-3-(2-(4-methoxyphenyl)-2-oxoethyl)indolin-2-one 98%
- Packaging250MG
- Price$195
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberQ65696
- Product description4,7-dichloro-3-hydroxy-3-(2-(4-methoxyphenyl)-2-oxoethyl)indolin-2-one 98%
- Packaging250MG
- Price$195
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberQ65696
- Product description4,7-dichloro-3-hydroxy-3-(2-(4-methoxyphenyl)-2-oxoethyl)indolin-2-one 98%
- Packaging5G
- Price$1620
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberQ65696
- Product description4,7-dichloro-3-hydroxy-3-(2-(4-methoxyphenyl)-2-oxoethyl)indolin-2-one 98%
- Packaging5G
- Price$1620
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberQ65696
- Product description4,7-dichloro-3-hydroxy-3-(2-(4-methoxyphenyl)-2-oxoethyl)indolin-2-one 98%
- Packaging1G
- Price$405
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberQ65696
- Product description4,7-dichloro-3-hydroxy-3-(2-(4-methoxyphenyl)-2-oxoethyl)indolin-2-one 98%
- Packaging1G
- Price$405
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product numberSYN5754
- Product descriptionYK-4-279
- Packaging100mg
- Price$567
- Updated2021-12-16
- Buy
- ManufacturerAlichem
- Product number1037184443
- Product description4,7-Dichloro-1,3-dihydro-3-hydroxy-3-[2-(4-methoxyphenyl)-2-oxoethyl]-2H-indol-2-one
- Packaging250mg
- Price$714
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA008SO1 | 4,7-Dichloro-1,3-dihydro-3-hydroxy-3-[2-(4-methoxyphenyl)-2-oxoethyl]-2H-indol-2-one 98 | 5mg | $64 | 2026-05-28 | Buy |
| aablocks | AA008SO1 | 4,7-Dichloro-1,3-dihydro-3-hydroxy-3-[2-(4-methoxyphenyl)-2-oxoethyl]-2H-indol-2-one 99% | 100mg | $83 | 2026-05-28 | Buy |
| aablocks | AA008SO1 | 4,7-Dichloro-1,3-dihydro-3-hydroxy-3-[2-(4-methoxyphenyl)-2-oxoethyl]-2H-indol-2-one 98 | 2mg | $48 | 2026-05-28 | Buy |
| aablocks | AA008SO1 | 4,7-Dichloro-1,3-dihydro-3-hydroxy-3-[2-(4-methoxyphenyl)-2-oxoethyl]-2H-indol-2-one 98% | 250mg | $176 | 2026-05-28 | Buy |
| aablocks | AA008SO1 | 4,7-Dichloro-1,3-dihydro-3-hydroxy-3-[2-(4-methoxyphenyl)-2-oxoethyl]-2H-indol-2-one 98% | 1g | $463 | 2026-05-28 | Buy |
| aablocks | AA008SO1 | 4,7-Dichloro-1,3-dihydro-3-hydroxy-3-[2-(4-methoxyphenyl)-2-oxoethyl]-2H-indol-2-one 98% | 5g | $1653 | 2026-05-28 | Buy |
| Absolute Chiral | O3572-00-N | 4,7-dichloro-3-hydroxy-3-(2-(4-methoxyphenyl)-2-oxoethyl)indolin-2-one 95% | 250mg | $198 | 2026-05-23 | Buy |
| Absolute Chiral | O3572-00-N | 4,7-dichloro-3-hydroxy-3-(2-(4-methoxyphenyl)-2-oxoethyl)indolin-2-one 95% | 100mg | $98 | 2026-05-23 | Buy |
| ACHEMBLOCK | Q65696 | 4,7-dichloro-3-hydroxy-3-(2-(4-methoxyphenyl)-2-oxoethyl)indolin-2-one 98% | 250MG | $195 | 2026-05-25 | Buy |
| ACHEMBLOCK | Q65696 | 4,7-dichloro-3-hydroxy-3-(2-(4-methoxyphenyl)-2-oxoethyl)indolin-2-one 98% | 250MG | $195 | 2026-05-27 | Buy |
| ACHEMBLOCK | Q65696 | 4,7-dichloro-3-hydroxy-3-(2-(4-methoxyphenyl)-2-oxoethyl)indolin-2-one 98% | 5G | $1620 | 2026-05-25 | Buy |
| ACHEMBLOCK | Q65696 | 4,7-dichloro-3-hydroxy-3-(2-(4-methoxyphenyl)-2-oxoethyl)indolin-2-one 98% | 5G | $1620 | 2026-05-27 | Buy |
| ACHEMBLOCK | Q65696 | 4,7-dichloro-3-hydroxy-3-(2-(4-methoxyphenyl)-2-oxoethyl)indolin-2-one 98% | 1G | $405 | 2026-05-25 | Buy |
| ACHEMBLOCK | Q65696 | 4,7-dichloro-3-hydroxy-3-(2-(4-methoxyphenyl)-2-oxoethyl)indolin-2-one 98% | 1G | $405 | 2026-05-27 | Buy |
| AK Scientific | SYN5754 | YK-4-279 | 100mg | $567 | 2021-12-16 | Buy |
| Alichem | 1037184443 | 4,7-Dichloro-1,3-dihydro-3-hydroxy-3-[2-(4-methoxyphenyl)-2-oxoethyl]-2H-indol-2-one | 250mg | $714 | 2021-12-16 | Buy |
Properties
Melting point :149-151℃
Boiling point :608.9±55.0 °C(Predicted)
Density :1.456
storage temp. :Store at -20° C.
solubility :insoluble in H2O; ≥16.35 mg/mL in DMSO; ≥24.25 mg/mL in EtOH with ultrasonic
form :Powder
pka :10.43±0.20(Predicted)
color :White to off-white
Boiling point :608.9±55.0 °C(Predicted)
Density :1.456
storage temp. :Store at -20° C.
solubility :insoluble in H2O; ≥16.35 mg/mL in DMSO; ≥24.25 mg/mL in EtOH with ultrasonic
form :Powder
pka :10.43±0.20(Predicted)
color :White to off-white
Safety Information
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Description
ES-FLI1 is an oncogenic fusion protein found in Ewing’s sarcoma, a family of undifferentiated tumors that occur throughout the body. The binding of RNA helicase A (RHA) to ES-FLI1 promotes its oncogenic function. YK-4-279 is an inhibitor of protein-protein interactions between ES-FLI1 and RHA. At 10 μM, YK-4-279 blocks RHA binding to ES-FLI1 and induces apoptosis of a panel of Ewing’s sarcoma tumor cell lines with IC50 values ranging from 0.5-2 μM. At 1.5 mg per dose, YK-4-279 reduces the growth of Ewing’s sarcoma orthotopic xenografts in mice after treatment with the inhibitor for two weeks.More related product prices
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Suppliers and manufacturers
ATK CHEMICAL COMPANY LIMITED
SHANGHAI T&W PHARMACEUTICAL CO., LTD.
HANGZHOU CLAP TECHNOLOGY CO.,LTD
Dideu Industries Group Limited
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
ShenZhen Trendseen Biological Technology Co.,Ltd.
Zibo Hangyu Biotechnology Development Co., Ltd
![4,7-dichloro-3-hydroxy-3-[2-(4-methoxyphenyl)-2-oxoethyl]-1H-indol-2-one](https://img.chemicalbook.com/ProductImageEN/2019-12/small/6071f2ba-f93d-486f-9cdb-74f52151c90f.png){kind=small}
