heptelidic acid
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- $100 - $3764.2
- Product name: heptelidic acid
- CAS: 57710-57-3
- MF: C15H20O5
- MW: 280.32
- EINECS:
- MDL Number:
- Synonyms:heptelidic acid;(5aS,9S)-1,5a,6,7,8,9aα-Hexahydro-6β-(1-methylethyl)-1-oxospiro[2-benzoxepine-9(3H),2'-oxirane]-4-carboxylic acid;(5aS,9S)-1,5aβ,6,7,8,9aα-Hexahydro-6β-isopropyl-1-oxospiro[2-benzoxepine-9(3H),2'-oxirane]-4-carboxylic acid;Avocettin;Koningic acid;Spiro[2-benzoxepin-9(3H),2'-oxirane]-4-carboxylic acid, 1,5a,6,7,8,9a-hexahydro-6-(1-methylethyl)-1-oxo-, (2'S,5aS,6R,9aS)-
25 prices
Selected condition：
Brand
- aablocks
- Adipogen Life Sciences
- American Custom Chemicals Corporation
- AvaChem
- Biosynth
- Cayman Chemical
- ChemScene
- TRC
- Usbiological
Package
- 0.2mg
- 250ug
- 250μg
- 0.5mg
- 1mg
- 2mg
- 2.5mg
- 5MG
- 10mg
- 500??g
- Manufactureraablocks
- Product numberAA00EWPR
- Product descriptionHeptelidic acid ≥95%
- Packaging1mg
- Price$459
- Updated2026-05-28
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0118-C250
- Product descriptionHeptelidic acid ≥95%(HPLC)
- Packaging250μg
- Price$125
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0118-M001
- Product descriptionHeptelidicacid ≥95%(HPLC)
- Packaging1mg
- Price$320
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0118-M001
- Product descriptionHeptelidic acid ≥95%(HPLC)
- Packaging1mg
- Price$375
- Updated2026-05-06
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberPXT0002362
- Product descriptionHEPTELIDIC ACID 95.00%
- Packaging5MG
- Price$498.44
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number6472
- Product descriptionKoningic acid; Heptelidic acid 98%
- Packaging0.2mg
- Price$100
- Updated2026-05-22
- Buy
- ManufacturerAvaChem
- Product number6472
- Product descriptionKoningic acid; Heptelidic acid 98%
- Packaging1mg
- Price$260
- Updated2026-05-22
- Buy
- ManufacturerBiosynth
- Product numberHCA71057
- Product descriptionHeptelidic acid
- Packaging0.5mg
- Price$895.62
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberHCA71057
- Product descriptionHeptelidic acid
- Packaging1mg
- Price$1194.16
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberHCA71057
- Product descriptionHeptelidic acid
- Packaging2mg
- Price$1194.16
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberHCA71057
- Product descriptionHeptelidic acid
- Packaging5mg
- Price$2271.5
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberHCA71057
- Product descriptionHeptelidic acid
- Packaging10mg
- Price$3764.2
- Updated2026-06-04
- Buy
- ManufacturerCayman Chemical
- Product number14079
- Product descriptionHeptelidic Acid ≥95%
- Packaging1mg
- Price$459
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number14079
- Product descriptionHeptelidic Acid ≥95%
- Packaging1mg
- Price$397
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number14079
- Product descriptionHeptelidic Acid ≥95%
- Packaging250μg
- Price$127
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number14079
- Product descriptionHeptelidic Acid ≥95%
- Packaging250μg
- Price$153
- Updated2026-04-30
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00EWPR | Heptelidic acid ≥95% | 1mg | $459 | 2026-05-28 | Buy |
| Adipogen Life Sciences | AG-CN2-0118-C250 | Heptelidic acid ≥95%(HPLC) | 250μg | $125 | 2026-05-06 | Buy |
| Adipogen Life Sciences | AG-CN2-0118-M001 | Heptelidicacid ≥95%(HPLC) | 1mg | $320 | 2021-12-16 | Buy |
| Adipogen Life Sciences | AG-CN2-0118-M001 | Heptelidic acid ≥95%(HPLC) | 1mg | $375 | 2026-05-06 | Buy |
| American Custom Chemicals Corporation | PXT0002362 | HEPTELIDIC ACID 95.00% | 5MG | $498.44 | 2021-12-16 | Buy |
| AvaChem | 6472 | Koningic acid; Heptelidic acid 98% | 0.2mg | $100 | 2026-05-22 | Buy |
| AvaChem | 6472 | Koningic acid; Heptelidic acid 98% | 1mg | $260 | 2026-05-22 | Buy |
| Biosynth | HCA71057 | Heptelidic acid | 0.5mg | $895.62 | 2026-06-04 | Buy |
| Biosynth | HCA71057 | Heptelidic acid | 1mg | $1194.16 | 2026-06-04 | Buy |
| Biosynth | HCA71057 | Heptelidic acid | 2mg | $1194.16 | 2026-06-04 | Buy |
| Biosynth | HCA71057 | Heptelidic acid | 5mg | $2271.5 | 2026-06-04 | Buy |
| Biosynth | HCA71057 | Heptelidic acid | 10mg | $3764.2 | 2026-06-04 | Buy |
| Cayman Chemical | 14079 | Heptelidic Acid ≥95% | 1mg | $459 | 2026-04-30 | Buy |
| Cayman Chemical | 14079 | Heptelidic Acid ≥95% | 1mg | $397 | 2024-03-01 | Buy |
| Cayman Chemical | 14079 | Heptelidic Acid ≥95% | 250μg | $127 | 2024-03-01 | Buy |
| Cayman Chemical | 14079 | Heptelidic Acid ≥95% | 250μg | $153 | 2026-04-30 | Buy |
Properties
Boiling point :501.1±50.0 °C(Predicted)
Density :1.27±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml
form :A solid
pka :3.68±0.40(Predicted)
color :Colorless to off-white
LogP :2.034 (est)
Density :1.27±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml
form :A solid
pka :3.68±0.40(Predicted)
color :Colorless to off-white
LogP :2.034 (est)
Safety Information
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| Signal word: | Warning | ||||||||||||||||||||||||
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Description
Glyceraldehyde 3-phosphate dehydrogenase (GAPDH), a key enzyme in carbohydrate metabolism, reversibly catalyzes the conversion of GAP to 1,3-bisphosphoglycerate and NAD+. Heptelidic acid is a sesquiterpene lactone produced by the fungus T. koningii that was shown to have antibiotic activity against anaerobic bacteria such as Bacteroides. It acts as an irreversible inhibitor of GAPDH that binds to the cysteine-149 residue at the active site of the enzyme (Ki = 1.6 μM). It can selectively induce apoptosis in high-glycolytic cancer cells by inhibiting the generation of ATP in the glycolytic pathway. Heptelidic acid is also a selective and competitive inhibitor of mammalian DNA polymerases β and λ as well as terminal deoxynucleotidyl transferase in family X of DNA polymerases (Kis range from 5.2-9.5 μM).More related product prices
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