1,4-Diacetylbenzene synthesis
- Product Name:1,4-Diacetylbenzene
- CAS Number:1009-61-6
- Molecular formula:C10H10O2
- Molecular Weight:162.19
105-05-5
216 suppliers
$47.00/5mL
1009-61-6
164 suppliers
$9.00/250mg
Yield:1009-61-6 92%
Reaction Conditions:
with pyridine;N-hydroxyphthalimide;tetrabutylammonium tetrafluoroborate;oxygen in 2,2,2-trifluoroethanol;acetonitrile at 35;Electrolysis;
Steps:
2.2.1 Procedure for mono-oxidation
General procedure: An undivided cell was equipped with a magnet stirrer, platinum plate electrode (1.0×1.0×0.3 cm3), as the working electrode and counter electrode. Substrate (0.5 mmol),nBu4NBF4 (0.5 mmol, 164.6 mg), N-hydroxyphthalimide (NHPI, 0.1 mmol, 16.3 mg), and pyridine (1.0 mmol, 82 μL)were added to MeCN/2,2,2-trifluoroethan-1-ol (TFE) (5:1,3 mL). The electrolysis was conducted in an undivided cell equipped with O2 balloon at a constant current of 5 mA at room temperature (25-30 °C). When the reaction was completed, the solvent was removed under reduced pressure and the remaining crude product was purified by column chromatography over silica gel (petroleum ether/ethyl acetate(PE/EA)=30:1-10:1) to afford the corresponding aromatic ketone product.
References:
Li, Zhibin;Zhang, Yan;Li, Kuiliang;Zhou, Zhenghong;Zha, Zhenggen;Wang, Zhiyong [Science China Chemistry,2021,vol. 64,# 12,p. 2134 - 2141]
935-14-8
206 suppliers
$16.00/250mg
1009-61-6
164 suppliers
$9.00/250mg
42472-69-5
79 suppliers
$46.00/100mg
105-05-5
216 suppliers
$47.00/5mL
937-30-4
215 suppliers
$25.00/25g
1009-61-6
164 suppliers
$9.00/250mg
935-14-8
206 suppliers
$16.00/250mg
1009-61-6
164 suppliers
$9.00/250mg
42472-69-5
79 suppliers
$46.00/100mg
1009-61-6
164 suppliers
$9.00/250mg