1-PHENYLCYCLOHEXANOL synthesis
- Product Name:1-PHENYLCYCLOHEXANOL
- CAS Number:1589-60-2
- Molecular formula:C12H16O
- Molecular Weight:176.25
108-86-1
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$10.00/5g
108-94-1
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$12.00/50g
1589-60-2
119 suppliers
$47.67/10g
Yield:1589-60-2 97%
Reaction Conditions:
Stage #1: bromobenzenewith magnesium in diethyl ether at 35;
Stage #2: cyclohexanone in diethyl ether at 35; for 5 h;
Steps:
1.a a. Preparation of 1-phenylcyclohexanol.
Add bromobenzene (50g, .31mol), magnesium bar (8.13g, 0.33mol) in a 1000mL three-necked flask and dissolve in an appropriate amount 6 In the ether, it is triggered at 35°C. After the reaction is complete, add cyclohexanone (34.38g, 0.35mol), and react at 35°C. After 5 hours, TLC monitors the progress of the reaction. After the reaction is complete, add the reaction solution to a saturated aqueous solution of ammonium chloride, and use ether After extraction, the extract is dried and evaporated under reduced pressure to obtain the product. The yield is 97.0%.
References:
CN112939864,2021,A Location in patent:Paragraph 0050-0052
591-50-4
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108-94-1
602 suppliers
$12.00/50g
1589-60-2
119 suppliers
$47.67/10g
108-94-1
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$12.00/50g
100-58-3
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1589-60-2
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827-52-1
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1589-60-2
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771-98-2
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4144-62-1
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3262-89-3
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108-94-1
602 suppliers
$12.00/50g
1589-60-2
119 suppliers
$47.67/10g