(E)-1,1,1-trichloro-4-ethoxy-3-methylbut-3-en-2-one synthesis
- Product Name:(E)-1,1,1-trichloro-4-ethoxy-3-methylbut-3-en-2-one
- CAS Number:121781-57-5
- Molecular formula:C7H9Cl3O2
- Molecular Weight:231.5042
Yield:121781-57-5 100%
Reaction Conditions:
with pyridine in dichloromethane at -10 - 25; for 16 h;
Steps:
D2.2; D3.1
A mixture of (E) -1-ethoxyprop-l-ene (5.00 g, 58.05 ?unol) in pyridine (4.685 ml, 58.05 mmol) was added to at -100C stirring solution of 2, 2, 2-trichloroacetyl chloride (10.56 g, 58.05 mmol) in DCM (15 mL) at a rate of 6-10 drops/minute. After the addition was complete, the mixture was stirred at
References:
WO2008/11131,2008,A2 Location in patent:Page/Page column 224-225
