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127958-23-0

2-Dimethylaminomethylene-4-methoxy-3-oxo-butyric acid methyl ester synthesis

3synthesis methods
41051-15-4 Synthesis
Methyl 4-methoxyacetoacetate

41051-15-4
307 suppliers
$6.00/5g

4637-24-5 Synthesis
N,N-Dimethylformamide dimethyl acetal

4637-24-5
649 suppliers
$5.00/25g

2-Dimethylaminomethylene-4-methoxy-3-oxo-butyric acid methyl ester

127958-23-0
16 suppliers
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Yield:127958-23-0 100%

Reaction Conditions:

at 20; for 24 h;

References:

Toda, Narihiro;Hao, Xiaolin;Ogawa, Yasuyuki;Oda, Kozo;Yu, Ming;Fu, Zice;Chen, Yi;Kim, Yongjae;Lizarzaburu, Mike;Lively, Sarah;Lawlis, Shauna;Murakoshi, Michiko;Nara, Futoshi;Watanabe, Nobuaki;Reagan, Jeff D.;Tian, Hui;Fu, Angela;Motani, Alykhan;Liu, Qingxiang;Lin, Yi-Jyun;Zhuang, Run;Xiong, Yumei;Fan, Peter;Medina, Julio;Li, Leping;Izumi, Masanori;Okuyama, Ryo;Shibuya, Satoshi [ACS Medicinal Chemistry Letters,2013,vol. 4,# 8,p. 790 - 794] Location in patent:supporting information

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