2-(4-Chloro-phenyl)-1H-benzimidazole-5-carboxylic acid synthesis
- Product Name:2-(4-Chloro-phenyl)-1H-benzimidazole-5-carboxylic acid
- CAS Number:174422-14-1
- Molecular formula:C14H9ClN2O2
- Molecular Weight:272.69
104-88-1
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174422-14-1
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Yield:-
Steps:
Multi-step reaction with 2 steps
1: disodium metabisulfite / ethanol; lithium hydroxide monohydrate / 0 - 20 °C
2: N,N-dimethyl-formamide / 6 h / 130 °C
References:
Qi, Yunkun;Ma, Ruixin;Li, Xin;Hu, Yue;Ma, Siti;Cong, Chao;Ma, Xiaodong;Cui, Wenping;Ma, Shutao [Letters in drug design and discovery,2011,vol. 8,# 10,p. 966 - 971]
