2,3-DICHLORO-6-METHYLQUINOXALINE synthesis
- Product Name:2,3-DICHLORO-6-METHYLQUINOXALINE
- CAS Number:39267-05-5
- Molecular formula:C9H6Cl2N2
- Molecular Weight:213.06
6309-61-1
39267-05-5
GENERAL METHOD: N,N-dimethylformamide (0.5 mg, 0.0673 mmol) was slowly added dropwise to a suspension of 1-chlorobutane (20 mL) containing 2,3-dihydroxy-6-methylquinoxaline (2.0 g, 12.3 mmol) and thionyl chloride (2.92 g, 24.6 mmol). The reaction mixture was heated to reflux for 1 hour. After completion of the reaction, it was cooled to room temperature and the resulting needle-like crystals were collected by filtration, washed with ether and subsequently dried.
6309-61-1
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$5.00/100mg
39267-05-5
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$19.00/250mg
Yield:39267-05-5 96%
Reaction Conditions:
with thionyl chloride;N,N-dimethyl-formamide for 1 h;Reflux;
Steps:
General procedure for the chlorination of dihydroxyquinoxalines in 1-chlorobutane
General procedure: N,N-Dimethylformamide (0.5 mg, 0.0673 mmol) was added dropwise to a slurry of 2,3-dihydroxyquinoxaline (2.0 g,12.3 mmol) and thionyl chloride (2.92 g, 24.6 mmol) in1-chlorobutane (20 mL). The mixture was refluxed for 1h.Then cooled to ambient temperature, the obtained needles were filtered, washed with ethyl ether, and dried.
References:
Bouanane, Zohra;Bounekhel, Mahmoud;Elkolli, Meriem;Takfaoui, Abdelilah [Revue Roumaine de Chimie,2017,vol. 62,# 12,p. 903 - 906]
6309-61-1
64 suppliers
$5.00/100mg
39267-05-5
99 suppliers
$19.00/250mg
496-72-0
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$9.00/1g
39267-05-5
99 suppliers
$19.00/250mg
6309-61-1
64 suppliers
$5.00/100mg
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39267-05-5
99 suppliers
$19.00/250mg