2-(4-Acetamidobenzylidene)malononitrile synthesis
2synthesis methods
- Product Name:2-(4-Acetamidobenzylidene)malononitrile
- CAS Number:26088-79-9
- Molecular formula:C12H9N3O
- Molecular Weight:211.22
Yield: 90.6%
Reaction Conditions:
with piperidine in ethanol for 0.5 h;Heating / reflux;
Steps:
22.1
1. Step: N-[4-(2,2-Dicyanovinyl)phenyl]acetamide 32.6 g (0.2 mol) of 4-acetaminobenzaldehyde and 13.74 g (0.208 mol) of malononitrile are initially charged in 140 ml of ethanol, and 24 drops of piperidine are added. The mixture is stirred at reflux for 30 min. After cooling, the crystals are filtered off with suction and dried. Yield: 38.6 g (90.6% of theory) of product Mass spectrum: molecular mass calculated: 211, found [M+H]+=212
References:
Bayer Aktiengeselischaft US7135486, 2006, B1 Location in patent:Page/Page column 46
![Propanedinitrile, 2-[(4-aminophenyl)methylene]-](/CAS/20210111/GIF/17082-32-5.gif)
