2,4-DICHLORO-5-FLUOROBROMOBENZENE synthesis
- Product Name:2,4-DICHLORO-5-FLUOROBROMOBENZENE
- CAS Number:1481-63-6
- Molecular formula:C6H2BrCl2F
- Molecular Weight:243.89
1435-48-9
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$6.00/5g
1481-63-6
70 suppliers
$34.00/1g
Yield:1481-63-6 247 g
Reaction Conditions:
with iron(III) chloride;bromine in dichloromethane at 25 - 35;Reagent/catalyst;Temperature;Solvent;
Steps:
1; 8 Example 1 preparation of 2,4-dichloro-5-bromofluorobenzene
At room temperature (about 20 °C), add 165g of 2,4-dichlorofluorobenzene, 330.0g of dichloromethane, 10g of ferric chloride to the reaction flask, turn on stirring, maintain the system temperature of 25-35 °C and slowly add bromine dropwise, a total of 170g of bromine is added dropwise for 2 hours. After the end of the reaction, it was reduced to 15~20 °C, and 10% sodium sulfite aqueous solution was added dropwise until the reaction was also non-oxidizing, and the organic layer was degraded to obtain 2,4-dichloro-5-bromofluorobenzene solid 247g, with a gas chromatographic detection content of 98.3%.
References:
CN115677477,2023,A Location in patent:Paragraph 0104-0106; 0125-0127
348-64-1
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$20.00/1g
1481-63-6
70 suppliers
$34.00/1g