2,6-DICHLOROPHENYLACETONE synthesis
- Product Name:2,6-DICHLOROPHENYLACETONE
- CAS Number:93457-06-8
- Molecular formula:C9H8Cl2O
- Molecular Weight:203.07
19393-92-1
195 suppliers
$10.00/5g
67-64-1
0 suppliers
$19.10/10ml
93457-06-8
40 suppliers
$60.00/100mg
Yield:93457-06-8 70%
Reaction Conditions:
with potassium phosphate;C37H56ClPPd at 50; for 21 h;Sealed tube;Inert atmosphere;
Steps:
1-Arylacetones 7a-o; General Method
General procedure: A 20 mL vial equipped with a stirrer bar and rubber seal wascharged with the appropriate (het)aryl bromide 6 (2.4 mmol),K3PO4 (3 equiv), and P7 (2.5 mol%). The vial was sealed anddegassed by using three vacuum/N2 cycles before acetone (10.8mL) was added and the resulting mixture was heated to 50 °Cfor the appropriate time (Scheme 2). The mixture was thencooled to rt, diluted with EtOAc, and filtered through Celite,washing with additional EtOAc. The filtrate was evaporated todryness and purified by chromatography (silica gel).
References:
Ledgard, Andrew J.;Martin, Fionna M.;Mutton, Simon P.;Richardson, Jeffery;Walton, Lesley [Synlett,2020]
79-24-3
0 suppliers
$353.45/5gm:
83-38-5
452 suppliers
$6.00/10g
93457-06-8
40 suppliers
$60.00/100mg