2,6-Dimethylbenzyl chloride synthesis
- Product Name:2,6-Dimethylbenzyl chloride
- CAS Number:5402-60-8
- Molecular formula:C9H11Cl
- Molecular Weight:154.64
62285-58-9
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$7.00/250mg
5402-60-8
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$8.00/1g
Yield:5402-60-8 89.7%
Reaction Conditions:
with thionyl chloride
Steps:
16 Example 16
Example 16
2-(Chloromethyl)-1,3-dimethylbenzene
91.4 g [0.768 mol] of thionyl chloride in 100 ml of toluene are initially charged, heated to 72° C. and a solution of 100 g of 2,6-dimethylbenzyl alcohol of a purity of 74.7% in 700 ml of toluene is added dropwise thereto within an hour.
Further stirring is subsequently carried out for one hour at 72° C.
The excess thionyl chloride is distilled off, the residue is filtered over some Celite and concentrated under reduced pressure.
This gives 107.2 g of a brown oil which, according to GC/MS analysis, contains 71.0% of the title compound, which corresponds to a yield of 89.7% of theory.
GC/MS: m/e=154 (M+, 35Cl, 17%), 119 (M-35, 100%),
References:
US2021/403406,2021,A1
14920-81-1
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5402-60-8
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1123-56-4
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$16.00/5g
5402-60-8
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632-46-2
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$10.00/1g
5402-60-8
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87-62-7
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5402-60-8
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