2-Bromo-N-methylbenzenesulphonamide synthesis
- Product Name:2-Bromo-N-methylbenzenesulphonamide
- CAS Number:98192-14-4
- Molecular formula:C7H8BrNO2S
- Molecular Weight:250.11
2905-25-1
277 suppliers
$12.00/1g
74-89-5
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$13.44/25ML
98192-14-4
55 suppliers
$27.00/250mg
Yield:98192-14-4 99%
Reaction Conditions:
in ethanol; for 2 h;Reflux;
Steps:
2-Bromo-N-methylbenzenesulfonamide (20a); Typical Procedure
General procedure: To a solution of commercially available 2-bromobenzenesulfonyl chloride (18, 500 mg, 1.96 mmol) in EtOH (20 mL), MeNH2 (0.7 mL,7.83 mmol) was added and the mixture was refluxed for 2 h. The residual solvent was evaporated under reduced pressure and the crude product obtained was purified by column chromatography (10% EtOAc-PE) to afford 20a12 (484 mg, 99%) as a white solid; mp 99-101 °C; Rf = 0.20 (10% EtOAc-PE).
References:
Debnath, Sudarshan;Mondal, Shovan [Synthesis,2016,vol. 48,# 5,p. 710 - 722]
2905-25-1
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$12.00/1g
593-51-1
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$21.00/100g
98192-14-4
55 suppliers
$27.00/250mg
5183-78-8
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$21.00/1g
98192-14-4
55 suppliers
$27.00/250mg
80-43-3
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$36.70/100g
92748-09-9
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$6.00/250mg
98192-14-4
55 suppliers
$27.00/250mg
7154-66-7
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$10.00/5g
74-89-5
0 suppliers
$13.44/25ML
98192-14-4
55 suppliers
$27.00/250mg