2-ETHYNYLTOLUENE 97 synthesis
- Product Name:2-ETHYNYLTOLUENE 97
- CAS Number:766-47-2
- Molecular formula:C9H8
- Molecular Weight:116.16
3989-15-9
39 suppliers
$146.00/5g
766-47-2
119 suppliers
$11.00/250mg
Yield:766-47-2 87%
Reaction Conditions:
with potassium trimethylsilonate in dimethyl sulfoxide at 60; under 760.051 Torr; for 7 h;Catalytic behavior;Sealed tube;Reagent/catalyst;Solvent;
Steps:
21
2-[(trimethylsilyl)ethynyl]toluene (1 mmol), inorganic base potassium tert-butoxide (sodium) or potassium hydroxide (sodium) or potassium trimethylsilylate (sodium) (0.05 mmol), 2 mL of DMA or DMSO solvent was sequentially added to a 10 mL sealed tube, and the mixture was heated and stirred in a 60°C oil bath for 7 hours. The progress of the reaction was followed by TLC. The reaction was completed and an equivalent of mesitylene or n-undecane was added as a crude product. The exact yield of the product was determined by GC and GC-MS. According to GC and GC-MS, when DMSO is used as a reaction solvent, inorganic base potassium tert-butoxide (sodium) or potassium hydroxide (sodium) or potassium trimethylsilylate (sodium) is used as a catalyst, and the yields of the products are as follows: 59%, 66%, 68%, 76%, 87%, 83%. When DMA was used as the reaction solvent, the inorganic potassium tert-butoxide (sodium) or potassium hydroxide (sodium) or potassium trimethylsilylate (sodium) was used as the catalyst. The yield of the product was: 50%, 58%, respectively. 57%, 69%, 78%, 83%.
References:
Taizhou University;Yao Wubing CN107459438, 2017, A Location in patent:Paragraph 0056; 0057
615-37-2
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$5.00/5g
471-25-0
237 suppliers
$10.00/1g
766-47-2
119 suppliers
$11.00/250mg
90965-06-3
219 suppliers
$30.25/1g
529-20-4
342 suppliers
$5.00/5g
766-47-2
119 suppliers
$11.00/250mg
615-37-2
291 suppliers
$5.00/5g
1066-54-2
471 suppliers
$9.00/10g
766-47-2
119 suppliers
$11.00/250mg
615-37-2
291 suppliers
$5.00/5g
766-47-2
119 suppliers
$11.00/250mg