2-HYDROXY-5-NITROPHENYLACETYLENE synthesis
1synthesis methods
- Product Name:2-HYDROXY-5-NITROPHENYLACETYLENE
- CAS Number:885951-98-4
- Molecular formula:C8H5NO3
- Molecular Weight:163.13
Yield:885951-98-4 31%
Reaction Conditions:
Stage #1: carbon tetrabromide;5-Nitrosalicylaldehydewith triphenylphosphine in dichloromethane at 0; for 2.33333 h;
Stage #2: with n-butyllithium in tetrahydrofuran;hexane at -78; for 1 h;
References:
Dai, Ning;Hu, Weican;Qian, Guoying;Rong, Zhouting [Organic Letters,2020,vol. 22,# 8,p. 3286 - 3290] Location in patent:supporting information