2-Isopropylthioxanthone synthesis
- Product Name:2-Isopropylthioxanthone
- CAS Number:5495-84-1
- Molecular formula:C16H14OS
- Molecular Weight:254.35
5003-97-4
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5495-84-1
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Yield:5495-84-1 91%
Reaction Conditions:
with sulfuric acid in cyclohexane;Reflux;Solvent;Temperature;
Steps:
1-8 Example 2: Preparation of 2-isopropylthioxanthone
Take 136.2g (0.50mol)2-(4-isopropylphenylthio)benzoic acid was dispersed in 400 mL of cyclohexane.125.0 g of 98% sulfuric acid (1.25 mol) was slowly added dropwise under a water bath, and the mixture was dropped for 30 minutes.Slowly heat up, reflux and dehydrate, monitor the reaction according to the amount of water separated by TLC or liquid phase.After the reaction was completed, 150 mL of water was added to the temperature drop, stirred for 30 minutes, and allowed to stand for stratification.The organic phase is separated, washed with 150 mL of water, and then the solvent is distilled off.The residue was recrystallized from 250mL of anhydrous ethanol to give a pale yellow solid 115.8g,Namely: 2-isopropylthioxanthone, the content is 99.3%.
References:
CN109928951,2019,A Location in patent:Paragraph 0016-0026
4946-14-9
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446-52-6
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5495-84-1
375 suppliers
$11.00/25g