2'-Methoxycinnamaldehyde synthesis
- Product Name:2'-Methoxycinnamaldehyde
- CAS Number:1504-74-1
- Molecular formula:C10H10O2
- Molecular Weight:162.19
1504-61-6
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1504-74-1
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$7.00/100mg
Yield:1504-74-1 94%
Reaction Conditions:
with 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical;copper diacetate in water;acetonitrile at 20; for 4 h;Green chemistry;
Steps:
General procedure: A mixture of alcohol (5.0 mmol), Cu(OAc)2 (9.1 mg, 0.05 mmol), and TEMPO (7.8 mg, 0.05 mmol) in CH3CN/H2O (5/10 mL) was stirred at room temperature for specified time. After completion of the reaction (monitored by TLC, eluents: petroleum ether/ethyl acetate = 4/1), dichloromethane (10 mL) was added to the resulting mixture. The dichloromethane phase was separated, and the aqueous phase was further extracted with dichloromethane (10 mL × 2). The combined organic layers were dried over anhydrous sodium sulfate and concentrated to give a residue, which was purified by column chromatography (eluents: petroleum ether/ethyl acetate = 10/1) to provide the desired product.
References:
Jiang, Jian-An;Du, Jia-Lei;Wang, Zhan-Guo;Zhang, Zhong-Nan;Xu, Xi;Zheng, Gan-Lin;Ji, Ya-Fei [Tetrahedron Letters,2014,vol. 55,# 10,p. 1677 - 1681] Location in patent:supporting information
33538-83-9
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1504-74-1
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$7.00/100mg
75-07-0
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$14.00/5mL
135-02-4
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$10.00/10g
1504-74-1
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$7.00/100mg
75-27-4
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$24.10/48615
612-15-7
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$50.50/1g
1504-74-1
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$7.00/100mg
3698-28-0
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$106.00/5g
1504-74-1
210 suppliers
$7.00/100mg