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228710-83-6

2-chloro-1-(6-(2,5-dimethyl-1H-pyrrol-1-yl)pyridin-3-yl)ethanone synthesis

3synthesis methods
228710-82-5 Synthesis
5-bromo-2-(2,5-dimethyl-1H-pyrrol-1-yl)pyridine

228710-82-5
66 suppliers
$50.00/250mg

67442-07-3 Synthesis
2-CHLORO-N-METHOXY-N-METHYLACETAMIDE

67442-07-3
213 suppliers
$6.00/5g

2-chloro-1-(6-(2,5-dimethyl-1H-pyrrol-1-yl)pyridin-3-yl)ethanone

228710-83-6
9 suppliers
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Yield:228710-83-6 82%

Reaction Conditions:

with hydrogenchloride;n-butyllithium in hexane;tert-butyl methyl ether at -78 - -65; for 2 h;Inert atmosphere;

References:

Scott, Robert W.;Fox, Darrell E.;Wong, John W.;Burns, Michael P. [Organic Process Research and Development,2004,vol. 8,# 4,p. 587 - 592]

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