4-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-2-nitroaniline synthesis

10synthesis methods

Product Name:4-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-2-nitroaniline
CAS Number:23623-05-4
Molecular formula:C18H20N6O2
Molecular Weight:352.3904

1635-61-6 Synthesis

1635-61-6
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$13.00/25g

4-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-2-nitroaniline

23623-05-4
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Yield:-

Steps:

Multi-step reaction with 3 steps
1: 60 percent / K₂CO₃ / dimethylformamide / 4.5 h / Heating
2: H₂ / 10percent Pd/C / methanol / 1.25 h / Ambient temperature
3: 1.171 g / AcOH / 12 h / 55 °C

References:

Harapanhalli;McLaughlin;Howell;Rao;Adelstein;Kassis [Journal of medicinal chemistry,1996,vol. 39,# 24,p. 4804 - 4809]

109-01-3 Synthesis

109-01-3
669 suppliers
$5.00/5G

23623-05-4
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References

5-(4-Methylpiperazin-1-yl)-2-nitroaniline

23491-48-7
158 suppliers
$11.00/250mg

23623-05-4
10 suppliers
inquiry

References

6393-40-4
199 suppliers
$15.00/1g

23623-05-4
10 suppliers
inquiry

References

4-(4-Methylpiperazino)-1,2-benzenediamine

54998-08-2
105 suppliers
$87.00/250mg

23623-05-4
10 suppliers
inquiry

References

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4-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-2-nitroaniline synthesis