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ChemicalBook CAS DataBase List (6-{2-[3-(2-Benzyloxy-phenylcarbamoyl)-5-(4-fluoro-phenyl)-2-isopropyl-4-phenyl-pyrrol-1-yl]-ethyl}-2,2-dimethyl-[1,3]-dioxane-4-yl)-acetic Acid, tert-Butyl Ester
265989-39-7

(6-{2-[3-(2-Benzyloxy-phenylcarbamoyl)-5-(4-fluoro-phenyl)-2-isopropyl-4-phenyl-pyrrol-1-yl]-ethyl}-2,2-dimethyl-[1,3]-dioxane-4-yl)-acetic Acid, tert-Butyl Ester synthesis

8synthesis methods
20012-63-9 Synthesis
2-BENZYLOXYANILINE

20012-63-9
160 suppliers
$19.00/1g

(6-{2-[3-(2-Benzyloxy-phenylcarbamoyl)-5-(4-fluoro-phenyl)-2-isopropyl-4-phenyl-pyrrol-1-yl]-ethyl}-2,2-dimethyl-[1,3]-dioxane-4-yl)-acetic Acid, tert-Butyl Ester

265989-39-7
12 suppliers
inquiry

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Yield:-

Steps:

Multi-step reaction with 4 steps
1: 76 percent / toluene / Heating
2: β-alanine; glacial acetic acid / hexane / Heating
3: 3-ethyl-5-(2-hydroxyethyl)-4-methylthiazolium bromide; triethylamine / ethanol / Heating
4: pivalic acid / tetrahydrofuran; toluene; heptane / Heating

References:

Chen, Bang-Chi;Sundeen, Joseph E.;Guo, Peng;Bednarz, Mark S.;Hangeland, Jon J.;Ahmed, Syed Z.;Jemal, Mohammed [Journal of labelled compounds and radiopharmaceuticals,2000,vol. 43,# 3,p. 261 - 270]

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