1-(2-HYDROXY-5-METHYLPHENYL)-3-PHENYL-1,3-PROPANEDIONE synthesis
- Product Name:1-(2-HYDROXY-5-METHYLPHENYL)-3-PHENYL-1,3-PROPANEDIONE
- CAS Number:29976-82-7
- Molecular formula:C16H14O3
- Molecular Weight:254.28
4010-19-9
29976-82-7
2-Benzoyloxy-5-methylacetophenone (I) (5 g, 19.6 mmol) was reacted with 15 g of powdered hot KOH in 25 ml of pyridine and heated at 100 °C for 30 min. After completion of the reaction, the reaction mixture was slowly poured into pre-cooled and acidified (6N HCl) ice water. Subsequently, the precipitated yellow precipitate was collected by filtration. The resulting solid residue was dried under vacuum. The crude product 1-(2-hydroxy-5-methylphenyl)-3-phenylpropane-1,3-dione (II) was purified by recrystallization from petroleum ether, resulting in yellow bright plate-like crystals. Yield: 75%; mass of isolated product: 3.73 g; melting point: 95 °C (literature value: 94 °C [34]).
1450-72-2
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$6.00/1g
93-97-0
391 suppliers
$6.00/25g
29976-82-7
55 suppliers
$62.00/100mg
Yield:29976-82-7 86%
Reaction Conditions:
with barium dihydroxide in dimethyl sulfoxide; for 0.00694444 h;microwave irradiation;
References:
Lamba;Kumar, Suresh;Makrandi [Journal of Chemical Research,2006,# 2,p. 133 - 134]
4010-19-9
16 suppliers
$297.00/1g
29976-82-7
55 suppliers
$62.00/100mg
1450-72-2
213 suppliers
$6.00/1g
93-89-0
543 suppliers
$13.00/100g
29976-82-7
55 suppliers
$62.00/100mg
1450-72-2
213 suppliers
$6.00/1g
65-85-0
1467 suppliers
$10.00/25g
29976-82-7
55 suppliers
$62.00/100mg
1450-72-2
213 suppliers
$6.00/1g
29976-82-7
55 suppliers
$62.00/100mg