3-(2-HYDROXY-ETHOXY)-BENZOIC ACID synthesis
- Product Name:3-(2-HYDROXY-ETHOXY)-BENZOIC ACID
- CAS Number:25781-99-1
- Molecular formula:C9H10O4
- Molecular Weight:182.17
124-38-9
724 suppliers
$214.00/14L
6161-83-7
27 suppliers
$155.00/50mg
25781-99-1
22 suppliers
$499.13/5MG
Yield:25781-99-1 50%
Reaction Conditions:
Stage #1: 2-(3-chlorophenoxy)ethanolwith n-butyllithium;magnesium(2-ethoxyethylate)2 in tetrahydrofuran at -78; for 0.25 h;deprotonation;
Stage #2: with lithium dihydronaphthylide radical in tetrahydrofuran at -78 - -50; for 0.333333 h;lithium-halogen exchange;
Stage #3: carbon dioxide in tetrahydrofuran;diethyl ether;Carboxylation;
References:
Salteris, Constantinos S.;Kostas, Ioannis D.;Micha-Screttas, Maria;Steele, Barry R.;Heropoulos, George A.;Screttas, Constantinos G.;Terzis, Aris [Journal of Organometallic Chemistry,1999,vol. 590,# 1,p. 63 - 70]
42772-85-0
94 suppliers
$58.00/100mg
99-06-9
527 suppliers
$5.00/25g
25781-99-1
22 suppliers
$499.13/5MG
99-06-9
527 suppliers
$5.00/25g
107-07-3
0 suppliers
$23.80/50ml
25781-99-1
22 suppliers
$499.13/5MG